Lysine 624 of the Amyloid Precursor Protein (APP) Is a Critical Determinant of Amyloid β Peptide Length
Kukar, Thomas L., Ladd, Thomas B., Robertson, Paul, Pintchovski, Sean A., Moore, Brenda, Bann, Maralyssa A., Ren, Zhao, Jansen-West, Karen, Malphrus, Kim, Eggert, Simone, Maruyama, Hiroko, Cottrell, Barbara A., Das, Pritam, Basi, Guriqbal S., Koo, Edward H., Golde, Todd E.
Published in The Journal of biological chemistry (18.11.2011)
Published in The Journal of biological chemistry (18.11.2011)
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Crystal structure reveals conservation of amyloid-[beta] conformation recognized by 3D6 following humanization to bapineuzumab
Feinberg, Hadar, Saldanha, Josñ W, Diep, Linnea, Goel, Amita, Widom, Angela, Veldman, Geertruida M, Weis, William I, Schenk, Dale, Basi, Guriqbal S
Published in Alzheimer's research & therapy (02.06.2014)
Published in Alzheimer's research & therapy (02.06.2014)
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Comparison of Apoptosis in Wild-Type and Fas-Resistant Cells: Chemotherapy-Induced Apoptosis Is Not Dependent on Fas/Fas Ligand Interactions
Eischen, Christine M., Kottke, Timothy J., Martins, Luis M., Basi, Guriqbal S., Tung, Jay S., Earnshaw, William C., Leibson, Paul J., Kaufmann, Scott H.
Published in Blood (01.08.1997)
Published in Blood (01.08.1997)
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Discovery of a novel [3.2.1] benzo fused bicyclic sulfonamide-pyrazoles as potent, selective and efficacious [gamma]-secretase inhibitors
Ye, Xiaocong M, Konradi, Andrei W, Sun, Minghua, Yuan, Shendong, Aubele, Danielle L, Dappen, Michael, Dressen, Darren, Garofalo, Albert W, Jagodzinski, Jacek J, Latimer, Lee, Probst, Gary D, Sham, Hing L, Wone, David, Xu, Ying-zi, Ness, Daniel, Brigham, Elizabeth, Kwong, Grace T, Willtis, Chris, Tonn, George, Goldbach, Erich, Quinn, Kevin P, Zhang, Hongbin H, Sauer, John-Michael, Bova, Michael, Basi, Guriqbal S
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease
Basi, Guriqbal S, Hemphill, Susanna, Brigham, Elizabeth F, Liao, Anna, Aubele, Danielle L, Baker, Jeanne, Barbour, Robin, Bova, Michael, Chen, Xiao-Hua, Dappen, Michael S, Eichenbaum, Tovah, Goldbach, Erich, Hawkinson, Jon, Lawler-Herbold, Rose, Hu, Kang, Hui, Terence, Jagodzinski, Jacek J, Keim, Pamela S, Kholodenko, Dora, Latimer, Lee H, Lee, Mike, Marugg, Jennifer, Mattson, Matthew N, McCauley, Scott, Miller, James L, Motter, Ruth, Mutter, Linda, Neitzel, Martin L, Ni, Huifang, Nguyen, Lan, Quinn, Kevin, Ruslim, Lany, Semko, Christopher M, Shapiro, Paul, Smith, Jenifer, Soriano, Ferdie, Szoke, Balazs, Tanaka, Kevin, Tang, Pearl, Tucker, John A, Ye, Xiacong Michael, Yu, Mei, Wu, Jing, Xu, Ying-Zi, Garofalo, Albert W, Sauer, John Michael, Konradi, Andrei W, Ness, Daniel, Shopp, George, Pleiss, Michael A, Freedman, Stephen B, Schenk, Dale
Published in Alzheimer's research & therapy (29.12.2010)
Published in Alzheimer's research & therapy (29.12.2010)
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Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis
Martins, Luis M., Kottke, Timothy, Mesner, Peter W., Basi, Guriqbal S., Sinha, Sukanto, Frigon, Normand, Tatar, Eric, Tung, Jay S., Bryant, Karin, Takahashi, Atsushi, Svingen, Phyllis A., Madden, Benjamin J., McCormick, Daniel J., Earnshaw, William C., Kaufmann, Scott H.
Published in The Journal of biological chemistry (14.03.1997)
Published in The Journal of biological chemistry (14.03.1997)
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Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid β-related Behavioral Deficits in a Mouse Model of Alzheimer Disease
Guriqbal S. Basi, Hadar Feinberg, Farshid Oshidari, John Anderson, Robin Barbour, Jeanne Baker, Thomas A. Comery, Linnea Diep, Davinder Gill, Kelly Johnson-Wood, Amita Goel, Katerina Grantcharova, Mike Lee, Jingzhi Li, Anthony Partridge, Irene Griswold-Prenner, Nicolas Piot, Don Walker, Angela Widom, Menelas N. Pangalos, Peter Seubert, J. Steven Jacobsen, Dale Schenk, William I. Weis
Published in The Journal of biological chemistry (29.01.2010)
Published in The Journal of biological chemistry (29.01.2010)
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Comparison of Caspase Activation and Subcellular Localization in HL-60 and K562 Cells Undergoing Etoposide-Induced Apoptosis
Martins, Luis M., Mesner, Peter W., Kottke, Timothy J., Basi, Guriqbal S., Sinha, Sukanto, Tung, Jay S., Svingen, Phyllis A., Madden, Benjamin J., Takahashi, Atsushi, McCormick, Daniel J., Earnshaw, William C., Kaufmann, Scott H.
Published in Blood (01.12.1997)
Published in Blood (01.12.1997)
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Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and Efficacious g-Secretase Inhibitors
Ye, Xiaocong M, Konradi, Andrei W, Smith, Jenifer, Xu, Ying-Zi, Dressen, Darren, Garofalo, Albert W, Marugg, Jennifer, Sham, Hing L, Truong, Anh P, Jagodzinski, Jacek, Pleiss, Michael, Zhang, Hongbin, Goldbach, Erich, Sauer, John-Michael, Brigham, Elizabeth, Bova, Michael, Basi, Guriqbal S
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
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Polo-like Kinase 2 (PLK2) Phosphorylates {alpha}-Synuclein at Serine 129 in Central Nervous System
Inglis, Kelly J, Chereau, David, Brigham, Elizabeth F, Chiou, San-San, Schobel, Susanne, Frigon, Normand L, Yu, Mei, Caccavello, Russell J, Nelson, Seth, Motter, Ruth, Wright, Sarah, Chian, David, Santiago, Pamela, Soriano, Ferdie, Ramos, Carla, Powell, Kyle, Goldstein, Jason M, Babcock, Michael, Yednock, Ted, Bard, Frederique, Basi, Guriqbal S, Sham, Hing, Chilcote, Tamie J, McConlogue, Lisa, Griswold-Prenner, Irene, Anderson, John P
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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Journal Article
Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System
Kelly J. Inglis, David Chereau, Elizabeth F. Brigham, San-San Chiou, Susanne Schöbel, Normand L. Frigon, Mei Yu, Russell J. Caccavello, Seth Nelson, Ruth Motter, Sarah Wright, David Chian, Pamela Santiago, Ferdie Soriano, Carla Ramos, Kyle Powell, Jason M. Goldstein, Michael Babcock, Ted Yednock, Frederique Bard, Guriqbal S. Basi, Hing Sham, Tamie J. Chilcote, Lisa McConlogue, Irene Griswold-Prenner, John P. Anderson
Published in The Journal of biological chemistry (30.01.2009)
Published in The Journal of biological chemistry (30.01.2009)
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P1‐035: Pharmacokinetic and pharmacodynamic analysis of a novel gamma secretase inhibitor in a non‐transgenicA‐beta mouse efficacy model
Quinn, Kevin P., Kuwabara‐Wagg, Jonathan, Brigham, Elizabeth, Cabrera, Cristian, Goldbach, Erich, Dreyer, Mark, Hu, Kang, Lee, Mike, Green, Michelle, Ness, Daniel, Santiago, Pamela, Samant, Bhushan, Soriano, Ferdie, Webb, Steve, Basi, Guriqbal S., Sauer, John‐Michael
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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P4‐019: Pharmacokinetic and pharmacodynamic analysis of a novel gamma secretase inhibitor in a nontransgenic A‐beta mouse efficacy model
Quinn, Kevin P., Kuwabara‐Wagg, Jonathan, Brigham, Elizabeth, Cabrera, Cristian, Goldbach, Erich, Dreyer, Mark, Hu, Kang, Lee, Mike, Green, Michelle, Ness, Daniel, Santiago, Pamela, Samant, Bhushan, Soriano, Ferdie, Webb, Steve, Basi, Guriqbal S., Sauer, John‐Michael
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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P4-330: Substrate concentration dependent inhibition of gamma secretase by novel inhibitors
Hemphill, Susanna S., Ren, Zhao, Neitzel, Martin L., Marugg, Jennifer L., Jagodzinski, Jacek, Latimer, Lee H., Pleiss, Michael A., Freedman, Stephen B., Sinha, Sukanto, Shapiro, I. Paul, Basi, Guriqbal S.
Published in Alzheimer's & dementia (01.07.2006)
Published in Alzheimer's & dementia (01.07.2006)
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