Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6
Toogood, Peter L, Harvey, Patricia J, Repine, Joseph T, Sheehan, Derek J, VanderWel, Scott N, Zhou, Hairong, Keller, Paul R, McNamara, Dennis J, Sherry, Debra, Zhu, Tong, Brodfuehrer, Joanne, Choi, Chung, Barvian, Mark R, Fry, David W
Published in Journal of medicinal chemistry (07.04.2005)
Published in Journal of medicinal chemistry (07.04.2005)
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Journal Article
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies
Vergne, Fabrice, Bernardelli, Patrick, Lorthiois, Edwige, Pham, Nga, Proust, Emmanuelle, Oliveira, Chrystelle, Mafroud, Abdel-Kader, Royer, Frederique, Wrigglesworth, Roger, Schellhaas, Jennifer, Barvian, Mark, Moreau, François, Idrissi, Moulay, Tertre, Anita, Bertin, Bernadette, Coupe, Magali, Berna, Patrick, Soulard, Patricia
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
Published in Bioorganic & medicinal chemistry letters (20.09.2004)
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Journal Article
DNA Damage Induced via 5,6-Dihydrothymid-5-yl in Single-Stranded Oligonucleotides
Greenberg, Marc M, Barvian, Mark R, Cook, Gary P, Goodman, Brian K, Matray, Tracy J, Tronche, Christopher, Venkatesan, Hariharan
Published in Journal of the American Chemical Society (26.02.1997)
Published in Journal of the American Chemical Society (26.02.1997)
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Journal Article
Discovery and structure-activity studies of a novel series of pyrido[2,3- d]pyrimidine tyrosine kinase inhibitors
Connolly, Cleo J.C., Hamby, James M., Schroeder, Mel C., Barvian, Mark, Lu, Gina H., Panek, Robert L., Amar, Aneesa, Shen, Cindy, Kraker, Alan J., Fry, David W., Klohs, Wayne D., Doherty, Annette M.
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
Published in Bioorganic & medicinal chemistry letters (23.09.1997)
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Journal Article
Reactivity of 5,6-Dihydro-5-hydroxythymid-6-yl Generated via Photoinduced Single Electron Transfer and the Role of Cyclohexa-1,4-diene in the Photodeoxygenation Process
Barvian, Mark R, Barkley, Robert M, Greenberg, Marc M
Published in Journal of the American Chemical Society (01.05.1995)
Published in Journal of the American Chemical Society (01.05.1995)
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Journal Article
Pyrido[2,3-d]pyrimidin-7-one Inhibitors of Cyclin-Dependent Kinases
Barvian, Mark, Boschelli, Diane H, Cossrow, Jennifer, Dobrusin, Ellen, Fattaey, Ali, Fritsch, Alex, Fry, David, Harvey, Patricia, Keller, Paul, Garrett, Michelle, La, Frances, Leopold, Wilbur, McNamara, Dennis, Quin, Maire, Trumpp-Kallmeyer, Susanne, Toogood, Peter, Wu, Zhipei, Zhang, Erli
Published in Journal of medicinal chemistry (30.11.2000)
Published in Journal of medicinal chemistry (30.11.2000)
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Journal Article
Preparation of N,N′-bis(aryl)guanidines from electron deficient amines via masked carbodiimides
Barvian, Mark R., Showalter, H.D. Hollis, Doherty, Annette M.
Published in Tetrahedron letters (29.09.1997)
Published in Tetrahedron letters (29.09.1997)
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Journal Article
Pyrido[2,3-d]pyrimidin-7-one Inhi-bitors of Cyclin-Dependent Kinases
Barvian, Mark, Boschelli, Diane H, Cossrow, Jennifer, Dobrusin, Ellen, Fattaey, Ali, Fritsch, Alex, Fry, David, Harvey, Patricia, Keller, Paul, Garrett, Michelle, La, Frances, Leopold, Wilbur, McNamara, Dennis, Quin, Maire, Trumpp-Kallmeyer, Susanne, Toogood, Peter, Wu, Zhipei, Zhang, Erli
Published in Journal of medicinal chemistry (15.03.2001)
Published in Journal of medicinal chemistry (15.03.2001)
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Journal Article
2-(pyridin-2-ylamino)-pyrido[2,3-D]pyrimidin-7-ones
Zhou, Hairong, Toogood, Peter Lawrence, Vanderwel, Scott Norman, Barvian, Mark, Booth, Richard John, Sheehan, Derek J, Repine, Joseph Thomas, Quinn, III, John
Year of Publication 26.11.2019
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Year of Publication 26.11.2019
Patent
Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity
Schroeder, Mel C, Hamby, James M, Connolly, Cleo J. C, Grohar, Patrick J, Winters, R. Thomas, Barvian, Mark R, Moore, Charles W, Boushelle, Stacey L, Crean, Sheila M, Kraker, Alan J, Driscoll, Denise L, Vincent, Patrick W, Elliott, William L, Lu, Gina H, Batley, Brian L, Dahring, Tawny K, Major, Terry C, Panek, Robert L, Doherty, Annette M, Showalter, H. D. Hollis
Published in Journal of medicinal chemistry (07.06.2001)
Published in Journal of medicinal chemistry (07.06.2001)
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Journal Article
2-(PYRIDIN-3-YLAMINO)-PYRIDO 2,3-D PYRIMIDIN-7-ONES
TOOGOOD, PETER, LAURENCE, BARVIAN, MARK, ROBERT, VANDERWEL, SCOTT, NORMAN
Year of Publication 08.11.2006
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Year of Publication 08.11.2006
Patent
2-(PYRIDIN-3-YLAMINO)-PYRIDO[2,3-D]PYRIMIDIN-7-ONES
VANDERWEL, SCOTT NORMAN, BARVIAN, MARK ROBERT, TOOGOOD, PETER LAURENCE
Year of Publication 09.09.2005
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Year of Publication 09.09.2005
Patent
2-(PYRIDIN-3-YLAMINO)-PYRIDO[2,3-D]PYRIMIDIN-7-ONES
TOOGOOD, PETER, LAURENCE, BARVIAN, MARK, ROBERT, VANDERWEL, SCOTT, NORMAN
Year of Publication 09.09.2005
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Year of Publication 09.09.2005
Patent