Head-to-head study of oxelumab and adalimumab in a mouse model of ulcerative colitis based on NOD/Scid IL2Rγnull mice reconstituted with human peripheral blood mononuclear cells
Jodeleit, Henrika, Winkelmann, Paula, Caesar, Janina, Sterz, Sebastian, Holdt, Lesca M, Beigel, Florian, Stallhofer, Johannes, Breiteneicher, Simone, Bartnik, Eckart, Leeuw, Thomas, Siebeck, Matthias, Gropp, Roswitha
Published in Disease models & mechanisms (01.01.2021)
Published in Disease models & mechanisms (01.01.2021)
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Journal Article
Determination of serum biomarkers in osteoarthritis patients:a previous interventional imaging study revisited
McAlindon, Timothy, Bartnik, Eckart, S Ried, Janina, Teichert, Lenore, Herrmann, Matthias, Flechsenhar, Klaus
Published in Journal of biomedical research (01.01.2017)
Published in Journal of biomedical research (01.01.2017)
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Journal Article
A Requirement for the CD44 Cytoplasmic Domain for Hyaluronan Binding, Pericellular Matrix Assembly, and Receptor-mediated Endocytosis in COS-7 Cells
Jiang, Hong, Peterson, Richard S., Wang, Weihua, Bartnik, Eckart, Knudson, Cheryl B., Knudson, Warren
Published in The Journal of biological chemistry (22.03.2002)
Published in The Journal of biological chemistry (22.03.2002)
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Journal Article
Differential Expression of Aggrecanase and Matrix Metalloproteinase Activity in Chondrocytes Isolated from Bovine and Porcine Articular Cartilage
Hughes, Clare E., Little, Chris B., Büttner, Frank H., Bartnik, Eckart, Caterson, Bruce
Published in The Journal of biological chemistry (13.11.1998)
Published in The Journal of biological chemistry (13.11.1998)
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Journal Article
Large‐scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis
Aigner, Thomas, Fundel, Katrin, Saas, Joachim, Gebhard, Pia M., Haag, Jochen, Weiss, Tilo, Zien, Alexander, Obermayr, Franz, Zimmer, Ralf, Bartnik, Eckart
Published in Arthritis and rheumatism (01.11.2006)
Published in Arthritis and rheumatism (01.11.2006)
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Journal Article
Neutrophilic granulocyte-derived B-cell activating factor supports B cells in skin lesions in hidradenitis suppurativa
Sabat, Robert, Šimaitė, Deimantė, Gudjonsson, Johann Eli, Brembach, Theresa-Charlotte, Witte, Katrin, Krause, Torben, Kokolakis, Georgios, Bartnik, Eckart, Nikolaou, Christos, Rill, Natascha, Coulibaly, Béma, Levin, Clément, Herrmann, Matthias, Salinas, Gabriela, Leeuw, Thomas, Volk, Hans-Dieter, Ghoreschi, Kamran, Wolk, Kerstin
Published in Journal of allergy and clinical immunology (01.04.2023)
Published in Journal of allergy and clinical immunology (01.04.2023)
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Journal Article
Oligosaccharide recognition by selectins: Synthesis and biological activity of multivalent sialyl lewis-X ligands
Kretzschmar, Gerhard, Sprengard, Ulrich, Kunz, Horst, Bartnik, Eckart, Schmidt, Wolfgang, Toepfer, Alexander, Hörsch, Brigitte, Krause, Manfred, Seiffge, Dirk
Published in Tetrahedron (20.11.1995)
Published in Tetrahedron (20.11.1995)
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Journal Article
The recombinant Link module of human TSG-6 suppresses cartilage damage in models of osteoarthritis: A potential disease-modifying OA drug
Drummond, Sheona P., Bartnik, Eckart, Kouvatsos, Nikolaos, Scott, Jenny L., Dyer, Douglas P., Thomson, Jennifer M., Price, Andrew J., Anand, Sanjay, Biant, Leela C., Leeuw, Thomas, Herrmann, Matthias, Milner, Caroline M., Day, Anthony J.
Published in Osteoarthritis and cartilage (01.10.2023)
Published in Osteoarthritis and cartilage (01.10.2023)
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Journal Article
Utilization of a Recombinant Substrate rAgg1 to Study the Biochemical Properties of Aggrecanase in Cell Culture Systems
Hughes, Clare E., Büttner, Frank H., Eidenmüller, Bernd, Caterson, Bruce, Bartnik, Eckart
Published in The Journal of biological chemistry (08.08.1997)
Published in The Journal of biological chemistry (08.08.1997)
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Translational drug discovery and development with the use of tissue‐relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy
Florian, Peter, Flechsenhar, Klaus R., Bartnik, Eckart, Ding‐Pfennigdorff, Danping, Herrmann, Matthias, Bryce, Paul J., Nestle, Frank O.
Published in Experimental dermatology (01.01.2020)
Published in Experimental dermatology (01.01.2020)
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Journal Article
The Combination of Patient Profiling and Preclinical Studies in a Mouse Model Based on NOD/Scid IL2Rγ null Mice Reconstituted With Peripheral Blood Mononuclear Cells From Patients With Ulcerative Colitis May Lead to Stratification of Patients for Treatment With Adalimumab
Jodeleit, Henrika, Caesar, Janina, Villarroel Aguilera, Christina, Sterz, Sebastian, Holdt, Lesca, Beigel, Florian, Stallhofer, Johannes, Breiteneicher, Simone, Bartnik, Eckart, Siebeck, Matthias, Gropp, Roswitha
Published in Inflammatory bowel diseases (04.03.2020)
Published in Inflammatory bowel diseases (04.03.2020)
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Journal Article
Sample Size Calculations for Detecting Disease‐Modifying Osteoarthritis Drug Effects on Knee Replacement Incidence in Clinical Trials: Data From the Osteoarthritis Initiative
Ried, Janina S., Flechsenhar, Klaus, Bartnik, Eckart, Crowther, Daniel, Dietrich, Axel, Eckstein, Felix
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2015)
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Journal Article
Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
Bau, Brigitte, Gebhard, Pia M., Haag, Jochen, Knorr, Thomas, Bartnik, Eckart, Aigner, Thomas
Published in Arthritis and rheumatism (01.10.2002)
Published in Arthritis and rheumatism (01.10.2002)
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Journal Article
Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the ‘aggrecanase’ and the MMP sites
BÜTTNER, Frank H., HUGHES, Clare E., MARGERIE, Daniel, LICHTE, Andrea, TSCHESCHE, Harald, CATERSON, Bruce, BARTNIK, Eckart
Published in Biochemical journal (01.07.1998)
Published in Biochemical journal (01.07.1998)
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Journal Article
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
Caglič, Dejan, Globisch, Anja, Kindermann, Maik, Lim, Ngee-Han, Jeske, Volker, Juretschke, Hans-Paul, Bartnik, Eckart, Weithmann, K. Ulrich, Nagase, Hideaki, Turk, Boris, Wendt, K. Ulrich
Published in Bioorganic & medicinal chemistry (01.02.2011)
Published in Bioorganic & medicinal chemistry (01.02.2011)
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Journal Article
Functional genomics of osteoarthritis: on the way to evaluate disease hypotheses
Aigner, Thomas, Bartnik, Eckart, Sohler, Florian, Zimmer, Ralf
Published in Clinical orthopaedics and related research (01.10.2004)
Published in Clinical orthopaedics and related research (01.10.2004)
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Journal Article
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation : Imaging Probes
CAGLIC, Dejan, GLOBISCH, Anja, WENDT, K. Ulrich, KINDERMANN, Maik, LIM, Ngee-Han, JESKE, Volker, JURETSCHKE, Hans-Paul, BARTNIK, Eckart, WEITHMANN, K. Ulrich, NAGASE, Hideaki, TURK, Boris
Published in Bioorganic & medicinal chemistry (2011)
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Published in Bioorganic & medicinal chemistry (2011)
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TAK1 downregulation reduces IL-1β induced expression of MMP13, MMP1 and TNF-alpha
Klatt, Andreas R., Klinger, Gabriele, Neumüller, Olga, Eidenmüller, Bernd, Wagner, Ingrid, Achenbach, Tatjana, Aigner, Thomas, Bartnik, Eckart
Published in Biomedicine & pharmacotherapy (01.02.2006)
Published in Biomedicine & pharmacotherapy (01.02.2006)
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Journal Article
Cleavage Site Specificity of Cathepsin K toward Cartilage Proteoglycans and Protease Complex Formation
Hou, W.-S., Li, Z., Büttner, F. H., Bartnik, E., Brömme, D.
Published in Biological chemistry (01.06.2003)
Published in Biological chemistry (01.06.2003)
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