Modeling of SGLT1 in Reconstituted Systems Reveals Apparent Ion-Dependencies of Glucose Uptake and Strengthens the Notion of Water-Permeable Apo States
Barta, Thomas, Sandtner, Walter, Wachlmayr, Johann, Hannesschlaeger, Christof, Ebert, Andrea, Speletz, Armin, Horner, Andreas
Published in Frontiers in physiology (15.06.2022)
Published in Frontiers in physiology (15.06.2022)
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The Effect of Buffers on Weak Acid Uptake by Vesicles
Hannesschlaeger, Christof, Barta, Thomas, Pechova, Hana, Pohl, Peter
Published in Biomolecules (Basel, Switzerland) (13.02.2019)
Published in Biomolecules (Basel, Switzerland) (13.02.2019)
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Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents
Huang, Kenneth H, Veal, James M, Fadden, R. Patrick, Rice, John W, Eaves, Jeron, Strachan, Jon-Paul, Barabasz, Amy F, Foley, Briana E, Barta, Thomas E, Ma, Wei, Silinski, Melanie A, Hu, Mei, Partridge, Jeffrey M, Scott, Anisa, DuBois, Laura G, Freed, Tiffany, Steed, Paul M, Ommen, Andy J, Smith, Emilie D, Hughes, Philip F, Woodward, Angela R, Hanson, Gunnar J, McCall, W. Stephen, Markworth, Christopher J, Hinkley, Lindsay, Jenks, Matthew, Geng, Lifeng, Lewis, Meredith, Otto, James, Pronk, Bert, Verleysen, Katleen, Hall, Steven E
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease
Becker, Daniel P, Barta, Thomas E, Bedell, Louis J, Boehm, Terri L, Bond, Brian R, Carroll, Jeffery, Carron, Chris P, DeCrescenzo, Gary A, Easton, Alan M, Freskos, John N, Funckes-Shippy, Chris L, Heron, Marcia, Hockerman, Susan, Howard, Carol Pearcy, Kiefer, James R, Li, Madeleine H, Mathis, Karl J, McDonald, Joseph J, Mehta, Pramod P, Munie, Grace E, Sunyer, Teresa, Swearingen, Craig A, Villamil, Clara I, Welsch, Dean, Williams, Jennifer M, Yu, Ying, Yao, Jun
Published in Journal of medicinal chemistry (23.09.2010)
Published in Journal of medicinal chemistry (23.09.2010)
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Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor
Carlson, David A, Franke, Aaron S, Weitzel, Douglas H, Speer, Brittany L, Hughes, Philip F, Hagerty, Laura, Fortner, Christopher N, Veal, James M, Barta, Thomas E, Zieba, Bartosz J, Somlyo, Avril V, Sutherland, Cindy, Deng, Jing Ti, Walsh, Michael P, MacDonald, Justin A, Haystead, Timothy A. J
Published in ACS chemical biology (20.12.2013)
Published in ACS chemical biology (20.12.2013)
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Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations
Cloudsdale, Ian S., Dickson, John K., Barta, Thomas E., Grella, Brian S., Smith, Emilie D., Kulp, John L., Guarnieri, Frank, Kulp, John L.
Published in Bioorganic & medicinal chemistry (01.08.2017)
Published in Bioorganic & medicinal chemistry (01.08.2017)
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Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90
BARTA, Thomas E, VEAL, James M, BARABASZ, Amy F, FOLEY, Briana E, OTTO, James, HALL, Steven E, RICE, John W, PARTRIDGE, Jeffrey M, FADDEN, R. Patrick, WEI MA, JENKS, Matthew, LIFENG GENG, HANSON, Gunnar J, HUANG, Kenneth H
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Journal Article
Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90
Huang, Kenneth H., Barta, Thomas E., Rice, John W., Smith, Emilie D., Ommen, Andy J., Ma, Wei, Veal, James M., Fadden, R. Patrick, Barabasz, Amy F., Foley, Briana E., Hughes, Philip F., Hanson, Gunnar J., Markworth, Christopher J., Silinski, Melanie, Partridge, Jeffrey M., Steed, Paul M., Hall, Steven E.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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MMP-13 selective alpha-sulfone hydroxamates: Identification of selective P1′ amides
Fobian, Yvette M., Freskos, John N., Barta, Thomas E., Bedell, Louis J., Heintz, Robert, Kassab, Darren J., Kiefer, James R., Mischke, Brent V., Molyneaux, John M., Mullins, Patrick, Munie, Grace E., Becker, Daniel P.
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Journal Article
Novel carbazole and acyl-indole antimitotics
Barta, Thomas E., Barabasz, Amy F., Foley, Briana E., Geng, Lifeng, Hall, Steven E., Hanson, Gunnar J., Jenks, Matthew, Ma, Wei, Rice, John W., Veal, James
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres
Barta, Thomas E., Becker, Daniel P., Bedell, Louis J., Easton, Alan M., Hockerman, Susan L., Kiefer, James, Munie, Grace E., Mathis, Karl J., Li, Madeleine H., Rico, Joseph G., Villamil, Clara I., Williams, Jennifer M.
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Journal Article
Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy
Becker, Daniel P, Villamil, Clara I, Barta, Thomas E, Bedell, Louis J, Boehm, Terri L, DeCrescenzo, Gary A, Freskos, John N, Getman, Daniel P, Hockerman, Susan, Heintz, Robert, Howard, Susan Carol, Li, Madeleine H, McDonald, Joseph J, Carron, Chris P, Funckes-Shippy, Chris L, Mehta, Pramod P, Munie, Grace E, Swearingen, Craig A
Published in Journal of medicinal chemistry (20.10.2005)
Published in Journal of medicinal chemistry (20.10.2005)
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Phase state of lipid bilayers modulates ammonia and water permeability through AtTip2;1
Barta, Thomas, Kumar, Deepak, Siligan, Christine, Wachlmayr, Johann, Kubar, Tomás, Horner, Andreas
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Quantification of Water Flux in Vesicular Systems
Hannesschläger, Christof, Barta, Thomas, Siligan, Christine, Horner, Andreas
Published in Scientific reports (04.06.2018)
Published in Scientific reports (04.06.2018)
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Journal Article
α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1
Becker, Daniel P, Barta, Thomas E, Bedell, Louis, DeCrescenzo, Gary, Freskos, John, Getman, Daniel P, Hockerman, Susan L, Li, Madeleine, Mehta, Pramod, Mischke, Brent, Munie, Grace E, Swearingen, Craig, Villamil, Clara I
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
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Biophysical quantification of unitary solute and solvent permeabilities to enable translation to membrane science
Wachlmayr, Johann, Samineni, Laxmicharan, Knyazev, Denis G., Barta, Thomas, Speletz, Armin, Yao, Chenhao, Oh, Hyeonji, Behera, Harekrushna, Ren, Tingwei, Kumar, Manish, Horner, Andreas
Published in Journal of membrane science (05.06.2023)
Published in Journal of membrane science (05.06.2023)
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Journal Article
Unitary Water Permeability Measurements via Lipid Vesicle Systems
Horner, Andreas, Barta, Thomas, Hannesschläger, Christof, Pohl, Peter
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
Quantification of Water Flux in Large Unilamellar Vesicles
Hannesschläger, Christof, Eckerstorfer, Anna, Speletz, Armin, Barta, Thomas, Wachlmayr, Johann, Horner, Andreas
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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