Activation of the human insulin receptor by non-insulin-related peptides
Kirk, Nicholas S, Chen, Qi, Wu, Yingzhe Ginger, Asante, Anastasia L, Hu, Haitao, Espinosa, Juan F, Martínez-Olid, Francisco, Margetts, Mai B, Mohammed, Faiz A, Kiselyov, Vladislav V, Barrett, David G, Lawrence, Michael C
Published in Nature communications (28.09.2022)
Published in Nature communications (28.09.2022)
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A Novel Glucokinase Activator Modulates Pancreatic Islet and Hepatocyte Function
Efanov, Alexander M, Barrett, David G, Brenner, Martin B, Briggs, Stephen L, Delaunois, Annie, Durbin, Jim D, Giese, Ulrich, Guo, Haihong, Radloff, Mark, Gil, Gema Sanz, Sewing, Sabine, Wang, Yong, Weichert, Andreas, Zaliani, Andrea, Gromada, Jesper
Published in Endocrinology (Philadelphia) (01.09.2005)
Published in Endocrinology (Philadelphia) (01.09.2005)
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The insulin secretory action of novel polycyclic guanidines: Discovery through open innovation phenotypic screening, and exploration of structure-activity relationships
Shaghafi, Michael B., Barrett, David G., Willard, Francis S., Overman, Larry E.
Published in Bioorganic & medicinal chemistry letters (15.02.2014)
Published in Bioorganic & medicinal chemistry letters (15.02.2014)
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Analyzing biological and artificial neural networks: challenges with opportunities for synergy?
Barrett, David GT, Morcos, Ari S, Macke, Jakob H
Published in Current opinion in neurobiology (01.04.2019)
Published in Current opinion in neurobiology (01.04.2019)
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Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors
He, Rongjun, Wang, Jifeng, Yu, Zhi-Hong, Moyers, Julie S., Michael, M. Dodson, Durham, Timothy B., Cramer, Jeff W., Qian, Yuewei, Lin, Amy, Wu, Li, Noinaj, Nicholas, Barrett, David G., Zhang, Zhong-Yin
Published in Journal of medicinal chemistry (27.10.2022)
Published in Journal of medicinal chemistry (27.10.2022)
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Regulation of GPR119 receptor activity with endocannabinoid-like lipids
Syed, Samreen K, Bui, Hai Hoang, Beavers, Lisa S, Farb, Thomas B, Ficorilli, James, Chesterfield, Amy K, Kuo, Ming-Shang, Bokvist, Krister, Barrett, David G, Efanov, Alexander M
Published in American journal of physiology: endocrinology and metabolism (15.12.2012)
Published in American journal of physiology: endocrinology and metabolism (15.12.2012)
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Sparse coding of birdsong and receptive field structure in songbirds
Greene, Garrett, Barrett, David G T, Sen, Kamal, Houghton, Conor
Published in Network (Bristol) (01.01.2009)
Published in Network (Bristol) (01.01.2009)
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Building machines that learn and think for themselves
Botvinick, Matthew, Barrett, David G. T., Battaglia, Peter, de Freitas, Nando, Kumaran, Darshan, Leibo, Joel Z, Lillicrap, Timothy, Modayil, Joseph, Mohamed, Shakir, Rabinowitz, Neil C., Rezende, Danilo J., Santoro, Adam, Schaul, Tom, Summerfield, Christopher, Wayne, Greg, Weber, Theophane, Wierstra, Daan, Legg, Shane, Hassabis, Demis
Published in The Behavioral and brain sciences (2017)
Published in The Behavioral and brain sciences (2017)
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A High-Throughput Assay for the Pancreatic Islet Beta-Cell Potassium Channel: Use in the Pharmacological Characterization of Insulin Secretagogues Identified from Phenotypic Screening
Song, Luyan, Barrett, David G, Cox, Karen L, Efanov, Alexander M, Syed, Samreen K, Tomandl, Dirk, Willard, Francis S
Published in Assay and drug development technologies (01.01.2021)
Published in Assay and drug development technologies (01.01.2021)
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Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5
Farb, Thomas B, Adeva, Marta, Beauchamp, Thomas J, Cabrera, Over, Coates, David A, Meredith, Tamika DeShea, Droz, Brian A, Efanov, Alexander, Ficorilli, James V, Gackenheimer, Susan L, Martinez-Grau, Maria A, Molero, Victoriano, Ruano, Gema, Statnick, Michael A, Suter, Todd M, Syed, Samreen K, Toledo, Miguel A, Willard, Francis S, Zhou, Xin, Bokvist, Krister B, Barrett, David G
Published in Endocrinology (Philadelphia) (01.11.2017)
Published in Endocrinology (Philadelphia) (01.11.2017)
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Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion
Syed, Samreen K, Kauffman, Audra L, Beavers, Lisa S, Alston, James T, Farb, Thomas B, Ficorilli, James, Marcelo, Marialuisa C, Brenner, Martin B, Bokvist, Krister, Barrett, David G, Efanov, Alexander M
Published in American journal of physiology: endocrinology and metabolism (15.11.2013)
Published in American journal of physiology: endocrinology and metabolism (15.11.2013)
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Activation of Prostaglandin E Receptor 4 Triggers Secretion of Gut Hormone Peptides GLP-1, GLP-2, and PYY
Coskun, Tamer, O'Farrell, Libbey S, Syed, Samreen K, Briere, Daniel A, Beavers, Lisa S, DuBois, Susan L, Michael, Mervyn D, Franciskovich, Jeffry B, Barrett, David G, Efanov, Alexander M
Published in Endocrinology (Philadelphia) (01.01.2013)
Published in Endocrinology (Philadelphia) (01.01.2013)
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Why neural networks find simple solutions: the many regularizers of geometric complexity
Dherin, Benoit, Munn, Michael, Rosca, Mihaela, Barrett, David G T
Published in arXiv.org (23.12.2022)
Published in arXiv.org (23.12.2022)
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Degradative Rearrangements of N-(t-Butyloxycarbonyl)-O-methanesulfonyl-hydroxamic Acids: A Novel, Reagent-Based Alternative to the Lossen Rearrangement1
Stafford, Jeffrey A, Gonzales, Stephen S, Barrett, David G, Suh, Edward M, Feldman, Paul L
Published in Journal of organic chemistry (25.12.1998)
Published in Journal of organic chemistry (25.12.1998)
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Synthesis and Evaluation of Potent and Selective β3 Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres
Uehling, David E, Donaldson, Kelly H, Deaton, David N, Hyman, Clifton E, Sugg, Elizabeth E, Barrett, David G, Hughes, Robert G, Reitter, Barbara, Adkison, Kim K, Lancaster, Mary E, Lee, Frank, Hart, Robert, Paulik, Mark A, Sherman, Bryan W, True, Timothy, Cowan, Conrad
Published in Journal of medicinal chemistry (31.01.2002)
Published in Journal of medicinal chemistry (31.01.2002)
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On the Origin of Implicit Regularization in Stochastic Gradient Descent
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