SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
Hou, Yixuan J, Chiba, Shiho, Halfmann, Peter, Ehre, Camille, Kuroda, Makoto, Dinnon, 3rd, Kenneth H, Leist, Sarah R, Schäfer, Alexandra, Nakajima, Noriko, Takahashi, Kenta, Lee, Rhianna E, Mascenik, Teresa M, Graham, Rachel, Edwards, Caitlin E, Tse, Longping V, Okuda, Kenichi, Markmann, Alena J, Bartelt, Luther, de Silva, Aravinda, Margolis, David M, Boucher, Richard C, Randell, Scott H, Suzuki, Tadaki, Gralinski, Lisa E, Kawaoka, Yoshihiro, Baric, Ralph S
Published in Science (18.12.2020)
Published in Science (18.12.2020)
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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
Sheahan, Timothy P., Sims, Amy C., Leist, Sarah R., Schäfer, Alexandra, Won, John, Brown, Ariane J., Montgomery, Stephanie A., Hogg, Alison, Babusis, Darius, Clarke, Michael O., Spahn, Jamie E., Bauer, Laura, Sellers, Scott, Porter, Danielle, Feng, Joy Y., Cihlar, Tomas, Jordan, Robert, Denison, Mark R., Baric, Ralph S.
Published in Nature Communications (10.01.2020)
Published in Nature Communications (10.01.2020)
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Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis
Gralinski, Lisa E, Sheahan, Timothy P, Morrison, Thomas E, Menachery, Vineet D, Jensen, Kara, Leist, Sarah R, Whitmore, Alan, Heise, Mark T, Baric, Ralph S
Published in mBio (09.10.2018)
Published in mBio (09.10.2018)
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Vaccination-induced herd immunity: Successes and challenges
Mallory, Michael L., Lindesmith, Lisa C., Baric, Ralph S.
Published in Journal of allergy and clinical immunology (01.07.2018)
Published in Journal of allergy and clinical immunology (01.07.2018)
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Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
Yang, Yang, Du, Lanying, Liu, Chang, Wang, Lili, Ma, Cuiqing, Tang, Jian, Baric, Ralph S., Jiang, Shibo, Li, Fang
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2014)
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Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans
Alter, Galit, Yu, Jingyou, Liu, Jinyan, Chandrashekar, Abishek, Borducchi, Erica N., Tostanoski, Lisa H., McMahan, Katherine, Jacob-Dolan, Catherine, Martinez, David R., Chang, Aiquan, Anioke, Tochi, Lifton, Michelle, Nkolola, Joseph, Stephenson, Kathryn E., Atyeo, Caroline, Shin, Sally, Fields, Paul, Kaplan, Ian, Robins, Harlan, Amanat, Fatima, Krammer, Florian, Baric, Ralph S., Le Gars, Mathieu, Sadoff, Jerald, de Groot, Anne Marit, Heerwegh, Dirk, Struyf, Frank, Douoguih, Macaya, van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H.
Published in Nature (London) (12.08.2021)
Published in Nature (London) (12.08.2021)
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Immunogenetic mechanisms driving norovirus GII.4 antigenic variation
Lindesmith, Lisa C, Beltramello, Martina, Donaldson, Eric F, Corti, Davide, Swanstrom, Jesica, Debbink, Kari, Lanzavecchia, Antonio, Baric, Ralph S
Published in PLoS pathogens (01.05.2012)
Published in PLoS pathogens (01.05.2012)
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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
Sheahan, Timothy P, Sims, Amy C, Graham, Rachel L, Menachery, Vineet D, Gralinski, Lisa E, Case, James B, Leist, Sarah R, Pyrc, Krzysztof, Feng, Joy Y, Trantcheva, Iva, Bannister, Roy, Park, Yeojin, Babusis, Darius, Clarke, Michael O, Mackman, Richard L, Spahn, Jamie E, Palmiotti, Christopher A, Siegel, Dustin, Ray, Adrian S, Cihlar, Tomas, Jordan, Robert, Denison, Mark R, Baric, Ralph S
Published in Science translational medicine (28.06.2017)
Published in Science translational medicine (28.06.2017)
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Differential Kinetics of Immune Responses Elicited by Covid-19 Vaccines
Collier, Ai-ris Y, Yu, Jingyou, McMahan, Katherine, Liu, Jinyan, Chandrashekar, Abishek, Maron, Jenny S, Atyeo, Caroline, Martinez, David R, Ansel, Jessica L, Aguayo, Ricardo, Rowe, Marjorie, Jacob-Dolan, Catherine, Sellers, Daniel, Barrett, Julia, Ahmad, Kunza, Anioke, Tochi, VanWyk, Haley, Gardner, Sarah, Powers, Olivia, Bondzie, Esther A, Wan, Huahua, Baric, Ralph S, Alter, Galit, Hacker, Michele R, Barouch, Dan H
Published in New England Journal of Medicine (18.11.2021)
Published in New England Journal of Medicine (18.11.2021)
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Airway Memory CD4+ T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses
Zhao, Jincun, Zhao, Jingxian, Mangalam, Ashutosh K., Channappanavar, Rudragouda, Fett, Craig, Meyerholz, David K., Agnihothram, Sudhakar, Baric, Ralph S., David, Chella S., Perlman, Stanley
Published in Immunity (Cambridge, Mass.) (21.06.2016)
Published in Immunity (Cambridge, Mass.) (21.06.2016)
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Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
Schäfer, Alexandra, Muecksch, Frauke, Lorenzi, Julio C C, Leist, Sarah R, Cipolla, Melissa, Bournazos, Stylianos, Schmidt, Fabian, Maison, Rachel M, Gazumyan, Anna, Martinez, David R, Baric, Ralph S, Robbiani, Davide F, Hatziioannou, Theodora, Ravetch, Jeffrey V, Bieniasz, Paul D, Bowen, Richard A, Nussenzweig, Michel C, Sheahan, Timothy P
Published in The Journal of experimental medicine (01.03.2021)
Published in The Journal of experimental medicine (01.03.2021)
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Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid
Iserman, Christiane, Roden, Christine A., Boerneke, Mark A., Sealfon, Rachel S.G., McLaughlin, Grace A., Jungreis, Irwin, Fritch, Ethan J., Hou, Yixuan J., Ekena, Joanne, Weidmann, Chase A., Theesfeld, Chandra L., Kellis, Manolis, Troyanskaya, Olga G., Baric, Ralph S., Sheahan, Timothy P., Weeks, Kevin M., Gladfelter, Amy S.
Published in Molecular Cell (17.12.2020)
Published in Molecular Cell (17.12.2020)
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Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
Martinez, David R, Schäfer, Alexandra, Leist, Sarah R, De la Cruz, Gabriela, West, Ande, Atochina-Vasserman, Elena N, Lindesmith, Lisa C, Pardi, Norbert, Parks, Robert, Barr, Maggie, Li, Dapeng, Yount, Boyd, Saunders, Kevin O, Weissman, Drew, Haynes, Barton F, Montgomery, Stephanie A, Baric, Ralph S
Published in Science (27.08.2021)
Published in Science (27.08.2021)
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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
Agostini, Maria L, Andres, Erica L, Sims, Amy C, Graham, Rachel L, Sheahan, Timothy P, Lu, Xiaotao, Smith, Everett Clinton, Case, James Brett, Feng, Joy Y, Jordan, Robert, Ray, Adrian S, Cihlar, Tomas, Siegel, Dustin, Mackman, Richard L, Clarke, Michael O, Baric, Ralph S, Denison, Mark R
Published in mBio (06.03.2018)
Published in mBio (06.03.2018)
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