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Eggert, Erik, Hillig, Roman C, Koehr, Silke, Stöckigt, Detlef, Weiske, Jörg, Barak, Naomi, Mowat, Jeffrey, Brumby, Thomas, Christ, Clara D, ter Laak, Antonius, Lang, Tina, Fernandez-Montalvan, Amaury E, Badock, Volker, Weinmann, Hilmar, Hartung, Ingo V, Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Kennedy, Steven, Li, Fengling, Vedadi, Masoud, Brown, Peter J, Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H, Stellfeld, Timo, Stresemann, Carlo
Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
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Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex
Schmidt, Michael R, Maritzen, Tanja, Kukhtina, Viktoria, Higman, Victoria A, Doglio, Laura, Barak, Naomi N, Strauss, Holger, Oschkinat, Hartmut, Dotti, Carlos G, Haucke, Volker
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2009)
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Identification of Small Molecules that Modulate Mutant p53 Condensation
Lemos, Clara, Schulze, Luise, Weiske, Joerg, Meyer, Hanna, Braeuer, Nico, Barak, Naomi, Eberspächer, Uwe, Werbeck, Nicolas, Stresemann, Carlo, Lange, Martin, Lesche, Ralf, Zablowsky, Nina, Juenemann, Katrin, Kamburov, Atanas, Luh, Laura Martina, Leissing, Thomas Markus, Mortier, Jeremie, Steckel, Michael, Steuber, Holger, Eis, Knut, Eheim, Ashley, Steigemann, Patrick
Published in iScience (25.09.2020)
Published in iScience (25.09.2020)
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Crystal Structure and Functional Analysis of the Protein Disulfide Isomerase-Related Protein ERp29
Barak, Naomi N., Neumann, Piotr, Sevvana, Madhumati, Schutkowski, Mike, Naumann, Kai, Malešević, Miroslav, Reichardt, Heike, Fischer, Gunter, Stubbs, Milton T., Ferrari, David M.
Published in Journal of molecular biology (06.02.2009)
Published in Journal of molecular biology (06.02.2009)
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Conserved Structural and Functional Properties of D-domain Containing Redox-active and -inactive Protein Disulfide Isomerase-related Protein Chaperones
Lippert, Undine, Diao, Daojun, Barak, Naomi N., Ferrari, David M.
Published in The Journal of biological chemistry (13.04.2007)
Published in The Journal of biological chemistry (13.04.2007)
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Concentration Dependence of the Unbound Partition Coefficient Kp uu and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors
Trünkle, Cornelius, Lechner, Christian, Korr, Daniel, Bouché, Léa, Barak, Naomi, Fernández-Montalván, Amaury, Süssmuth, Roderich D, Reichel, Andreas
Published in Drug metabolism and disposition (01.07.2020)
Published in Drug metabolism and disposition (01.07.2020)
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Discovery and Characterization of BAY-184: A New Potent and Selective Acylsulfonamide-Benzofuran In Vivo-Active KAT6AB Inhibitor
ter Laak, Antonius, Hillig, Roman C., Ferrara, Steven J., Korr, Daniel, Barak, Naomi, Lienau, Philip, Herbert, Simon, Fernández-Montalván, Amaury Ernesto, Neuhaus, Roland, Gorjánácz, Mátyás, Puetter, Vera, Badock, Volker, Bone, Wilhelm, Strathdee, Craig, Siegel, Franziska, Schatz, Christoph, Nowak-Reppel, Katrin, Doehr, Olaf, Gradl, Stefan, Hartung, Ingo V., Meyerson, Matthew, Bouché, Léa
Published in Journal of medicinal chemistry (14.11.2024)
Published in Journal of medicinal chemistry (14.11.2024)
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A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy
Böhnke, Niels, Berger, Markus, Griebenow, Nils, Rottmann, Antje, Erkelenz, Michael, Hammer, Stefanie, Berndt, Sandra, Günther, Judith, Wengner, Antje M., Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Jörißen, Hannah, Barak, Naomi, Bömer, Ulf, Hillig, Roman C., Eberspaecher, Uwe, Weiske, Jörg, Giese, Anja, Mumberg, Dominik, Nising, Carl Friedrich, Weinmann, Hilmar, Sommer, Anette
Published in Bioconjugate chemistry (15.06.2022)
Published in Bioconjugate chemistry (15.06.2022)
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Abstract 2907: Identification and optimization of a novel NAMPT inhibitor-based ADC payload class for cancer therapy
Böhnke, Niels, Berger, Markus, Griebenow, Nils, Giese, Anja, Günther, Judith, Sommer, Anette, Hammer, Stefanie, Berndt, Sandra, Wengner, Antje M., Beier, Rudolf, Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Joerissen, Hannah, Rottmann, Antje, Erkelenz, Michael, Barak, Naomi, Bömer, Ulf, Mumber, Dominik, Kreft, Bertolt, Linden, Lars, Nising, Carl Friedrich, Weinmann, Hilmar
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Concentration dependency of the unbound partition coefficient Kp uu and its application to correct for exposure related discrepancies between biochemical and cellular potency of KAT6A inhibitors
Trünkle, Cornelius, Lechner, Christian, Korr, Daniel, Bouché, Léa, Barak, Naomi, Fernández-Montalván, Amaury, Süssmuth, Roderich D, Reichel, Andreas
Published in Drug metabolism and disposition (01.05.2020)
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Published in Drug metabolism and disposition (01.05.2020)
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Abstract 5239: Probing the cancer epigenome: empowering target validation by open innovation
Hartung, Ingo V., Arrowsmith, Cheryl, Badock, Volker, Barak, Naomi, Berger, Markus, Brown, Peter J., Christ, Clara D., Eggert, Erik, Egner, Ursula, Fedorov, Oleg, Fernandez-Montalvan, Amaury E., Gorjanacz, Matyas, Haegebarth, Andrea, Haendler, Bernard, Hillig, Roman C., Holton, Simon H., Huber, Kilian V., Koo, Seong J., Laak, Antonius ter, Mueller, Susanne, Mueller-Fahrnow, Anke, Scholten, Cora, Siegel, Stephan, Stellfeld, Timo, Stoeckigt, Detlef, Stresemann, Carlo, Vedadi, Masoud, Weiske, Joerg, Weinmann, Hilmar
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 2829: Discovery and in vitro and in vivo characterization of aminopyrazoline-based SMYD2 inhibitors
Stresemann, Carlo, Hartung, Ingo, Stellfeld, Timo, Barak, Naomi, Mowat, Jeffrey, Christ, Clara, ter Laak, Antonius, Koehr, Silke, Weiske, Jörg, Hillig, Roman, Badock, Volker, Stoeckigt, Detlef, Ziegelbauer, Karl, Weinmann, Hilmar, Gekeler, Volker
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Year of Publication 09.06.2014
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Year of Publication 29.08.2024
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