Regulating the regulator: post-translational modification of RAS
Ahearn, Ian M., Haigis, Kevin, Bar-Sagi, Dafna, Philips, Mark R.
Published in Nature reviews. Molecular cell biology (01.01.2012)
Published in Nature reviews. Molecular cell biology (01.01.2012)
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Journal Article
Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer
Jang, Jung-Eun, Hajdu, Cristina H., Liot, Caroline, Miller, George, Dustin, Michael L., Bar-Sagi, Dafna
Published in Cell reports (Cambridge) (18.07.2017)
Published in Cell reports (Cambridge) (18.07.2017)
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Journal Article
Oncogenic Kras-Induced GM-CSF Production Promotes the Development of Pancreatic Neoplasia
Pylayeva-Gupta, Yuliya, Lee, Kyoung Eun, Hajdu, Cristina H., Miller, George, Bar-Sagi, Dafna
Published in Cancer cell (12.06.2012)
Published in Cancer cell (12.06.2012)
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Journal Article
Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein
Kamphorst, Jurre J, Nofal, Michel, Commisso, Cosimo, Hackett, Sean R, Lu, Wenyun, Grabocka, Elda, Vander Heiden, Matthew G, Miller, George, Drebin, Jeffrey A, Bar-Sagi, Dafna, Thompson, Craig B, Rabinowitz, Joshua D
Published in Cancer research (Chicago, Ill.) (01.02.2015)
Published in Cancer research (Chicago, Ill.) (01.02.2015)
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Journal Article
An orthosteric inhibitor of the Ras-Sos interaction
Patgiri, Anupam, Yadav, Kamlesh K, Arora, Paramjit S, Bar-Sagi, Dafna
Published in Nature chemical biology (17.07.2011)
Published in Nature chemical biology (17.07.2011)
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Journal Article
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
Commisso, Cosimo, Davidson, Shawn M., Soydaner-Azeloglu, Rengin G., Parker, Seth J., Kamphorst, Jurre J., Hackett, Sean, Grabocka, Elda, Nofal, Michel, Drebin, Jeffrey A., Thompson, Craig B., Rabinowitz, Joshua D., Metallo, Christian M., Vander Heiden, Matthew G., Bar-Sagi, Dafna
Published in Nature (London) (30.05.2013)
Published in Nature (London) (30.05.2013)
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Journal Article
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia
Pylayeva-Gupta, Yuliya, Das, Shipra, Handler, Jesse S, Hajdu, Cristina H, Coffre, Maryaline, Koralov, Sergei B, Bar-Sagi, Dafna
Published in Cancer discovery (01.03.2016)
Published in Cancer discovery (01.03.2016)
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Journal Article
The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers
Marzio, Antonio, Puccini, Joseph, Kwon, Youngho, Maverakis, Natalia K., Arbini, Arnaldo, Sung, Patrick, Bar-Sagi, Dafna, Pagano, Michele
Published in Molecular cell (17.01.2019)
Published in Molecular cell (17.01.2019)
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Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
Davidson, Shawn M, Jonas, Oliver, Keibler, Mark A, Hou, Han Wei, Luengo, Alba, Mayers, Jared R, Wyckoff, Jeffrey, Del Rosario, Amanda M, Whitman, Matthew, Chin, Christopher R, Condon, Kendall J, Lammers, Alex, Kellersberger, Katherine A, Stall, Brian K, Stephanopoulos, Gregory, Bar-Sagi, Dafna, Han, Jongyoon, Rabinowitz, Joshua D, Cima, Michael J, Langer, Robert, Vander Heiden, Matthew G
Published in Nature medicine (01.02.2017)
Published in Nature medicine (01.02.2017)
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Journal Article
EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion
Marzio, Antonio, Kurz, Emma, Sahni, Jennifer M., Di Feo, Giuseppe, Puccini, Joseph, Jiang, Shaowen, Hirsch, Carolina Alcantara, Arbini, Arnaldo A., Wu, Warren L., Pass, Harvey I., Bar-Sagi, Dafna, Papagiannakopoulos, Thales, Pagano, Michele
Published in Cell (06.01.2022)
Published in Cell (06.01.2022)
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Journal Article
Molecular pathways: targeting the dependence of mutant RAS cancers on the DNA damage response
Grabocka, Elda, Commisso, Cosimo, Bar-Sagi, Dafna
Published in Clinical cancer research (15.03.2015)
Published in Clinical cancer research (15.03.2015)
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Journal Article
Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer
Parker, Seth J, Amendola, Caroline R, Hollinshead, Kate E R, Yu, Qijia, Yamamoto, Keisuke, Encarnación-Rosado, Joel, Rose, Rebecca E, LaRue, Madeleine M, Sohn, Albert S W, Biancur, Doug E, Paulo, Joao A, Gygi, Steven P, Jones, Drew R, Wang, Huamin, Philips, Mark R, Bar-Sagi, Dafna, Mancias, Joseph D, Kimmelman, Alec C
Published in Cancer discovery (01.07.2020)
Published in Cancer discovery (01.07.2020)
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Journal Article
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
Ochi, Atsuo, Nguyen, Andrew H, Bedrosian, Andrea S, Mushlin, Harry M, Zarbakhsh, Saman, Barilla, Rocky, Zambirinis, Constantinos P, Fallon, Nina C, Rehman, Adeel, Pylayeva-Gupta, Yuliya, Badar, Sana, Hajdu, Cristina H, Frey, Alan B, Bar-Sagi, Dafna, Miller, George
Published in The Journal of experimental medicine (27.08.2012)
Published in The Journal of experimental medicine (27.08.2012)
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