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Synthesis of many different types of organic small molecules using one automated process

Synthesis of many different types of organic small molecules using one automated process

by Li, Junqi, Ballmer, Steven G., Gillis, Eric P., Fujii, Seiko, Schmidt, Michael J., Palazzolo, Andrea M. E., Lehmann, Jonathan W., Morehouse, Greg F., Burke, Martin D.
Published in Science (American Association for the Advancement of Science) (13.03.2015)

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Journal Article

라파마이신 유사체 화합물의 합성

라파마이신 유사체 화합물의 합성

by LI SHAOLING, HUANG XIAOJUN, BALLMER STEVEN G
Year of Publication 15.01.2024

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Patent

6-[설파닐]-3-[(3S,4S)-4-아미노-3-메틸-2-옥사-8-아자스피로[4.5]데칸-8-일]-5-메틸피라진-2-일｝메탄올의 고체 형태인 SHP2 저해제

6-[설파닐]-3-[(3S,4S)-4-아미노-3-메틸-2-옥사-8-아자스피로[4.5]데칸-8-일]-5-메틸피라진-2-일｝메탄올의 고체 형태인 SHP2 저해제

by LI SHAOLING, BALLMER STEVEN G
Year of Publication 15.02.2022

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Patent

SHP2 억제제를 제조하는 방법

SHP2 억제제를 제조하는 방법

by LI SHAOLING, GARNIER CELINE, ARNOLD MICKAEEL, BALLMER STEVEN G, LESZCZAK JEAN PIERRE
Year of Publication 21.12.2023

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Patent

ChemInform Abstract: Synthesis of Many Different Types of Organic Small Molecules Using One Automated Process

ChemInform Abstract: Synthesis of Many Different Types of Organic Small Molecules Using One Automated Process

by Li, Junqi, Ballmer, Steven G., Gillis, Eric P., Fujii, Seiko, Schmidt, Michael J., Palazzolo, Andrea M. E., Lehmann, Jonathan W., Morehouse, Greg F., Burke, Martin D.
Published in ChemInform (01.08.2015)

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Journal Article

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl} methanol, a SHP2 inhibitor

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl} methanol, a SHP2 inhibitor

by Ballmer, Steven G, Li, Shaoling
Year of Publication 11.01.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 30.05.2024

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, A SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, A SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 22.09.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 14.02.2024

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 13.04.2022

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Patent

FORMES SOLIDES DE (6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-MÉTHYL-2-OXA-8-AZASPIRO [4,5]DÉCAN-8-YL]-5-MÉTHYLPYRAZIN-2-YL)MÉTHANOL, UN INHIBITEUR DE SHP2

FORMES SOLIDES DE (6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-MÉTHYL-2-OXA-8-AZASPIRO [4,5]DÉCAN-8-YL]-5-MÉTHYLPYRAZIN-2-YL)MÉTHANOL, UN INHIBITEUR DE SHP2

by BALLMER, Steven G, LI, Shaoling
Year of Publication 13.04.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 16.11.2023

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 30.12.2021

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Patent

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl}methanol, an SHP2 inhibitor

Solid forms of {6-[(2-amino-3-chloropyridin-4-yl)sulfanyl]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-5-methylpyrazin-2-yl}methanol, an SHP2 inhibitor

by BALLMER, Steven G, LI, Shaoling
Year of Publication 09.12.2021

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Patent

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

SOLID FORMS OF {6-[(2-AMINO-3-CHLOROPYRIDIN-4-YL)SULFANYL]-3-[(3S,4S)-4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL]-5-METHYLPYRAZIN-2-YL}METHANOL, AN SHP2 INHIBITOR

by BALLMER, Steven G, LI, Shaoling
Year of Publication 19.08.2021

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 09.03.2023

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 22.12.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by HUANG, XIAOJUN, LI, SHAOLING, BALLMER, STEVEN G
Year of Publication 13.10.2022

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Patent

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS

by BALLMER, Steven G, HUANG, Xiaojun, LI, Shaoling
Year of Publication 13.10.2022

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Patent

PROCESS FOR PREPARING SHP2 INHIBITORS

PROCESS FOR PREPARING SHP2 INHIBITORS

by BALLMER, Steven G, ARNOLD, Mickaël, LI, Shaoling, GARNIER, Céline, LESZCZAK, Jean-Pierre
Year of Publication 06.06.2024

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Patent