Computer-Aided Drug Design towards New Psychotropic and Neurological Drugs
Dorahy, Georgia, Chen, Jake Zheng, Balle, Thomas
Published in Molecules (Basel, Switzerland) (30.01.2023)
Published in Molecules (Basel, Switzerland) (30.01.2023)
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Journal Article
CardioTox net: a robust predictor for hERG channel blockade based on deep learning meta-feature ensembles
Karim, Abdul, Lee, Matthew, Balle, Thomas, Sattar, Abdul
Published in Journal of cheminformatics (16.08.2021)
Published in Journal of cheminformatics (16.08.2021)
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Journal Article
Liquid lipases for enzymatic concentration of n-3 polyunsaturated fatty acids in monoacylglycerols via ethanolysis: Catalytic specificity and parameterization
He, Yongjin, Li, Jingbo, Kodali, Sitharam, Balle, Thomas, Chen, Bilian, Guo, Zheng
Published in Bioresource technology (01.01.2017)
Published in Bioresource technology (01.01.2017)
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Journal Article
The Anti-Nociceptive Effects of Nicotine in Humans: A Systematic Review and Meta-Analysis
Luo, Yujia, Yang, Yating, Schneider, Carl, Balle, Thomas
Published in Pharmaceuticals (Basel, Switzerland) (30.11.2023)
Published in Pharmaceuticals (Basel, Switzerland) (30.11.2023)
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Journal Article
Binding and Dynamics Demonstrate the Destabilization of Ligand Binding for the S688Y Mutation in the NMDA Receptor GluN1 Subunit
Chen, Jake Zheng, Church, William Bret, Bastard, Karine, Duff, Anthony P, Balle, Thomas
Published in Molecules (Basel, Switzerland) (15.05.2023)
Published in Molecules (Basel, Switzerland) (15.05.2023)
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Journal Article
Alternatively Spliced Isoforms of the P2X7 Receptor: Structure, Function and Disease Associations
De Salis, Sophie K. F., Li, Lanxin, Chen, Zheng, Lam, Kam Wa, Skarratt, Kristen K., Balle, Thomas, Fuller, Stephen J.
Published in International journal of molecular sciences (01.08.2022)
Published in International journal of molecular sciences (01.08.2022)
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Journal Article
Structure-Based Discovery of Dual-Target Hits for Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptors: In Silico Studies and In Vitro Confirmation
Oddsson, Sebastian, Kowal, Natalia M, Ahring, Philip K, Olafsdottir, Elin S, Balle, Thomas
Published in Molecules (Basel, Switzerland) (22.06.2020)
Published in Molecules (Basel, Switzerland) (22.06.2020)
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Journal Article
Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors
Olsen, Jeppe A, Balle, Thomas, Gajhede, Michael, Ahring, Philip K, Kastrup, Jette S
Published in PloS one (17.03.2014)
Published in PloS one (17.03.2014)
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Journal Article
Probing the Role of Backbone Hydrogen Bonds in Protein–Peptide Interactions by Amide-to-Ester Mutations
Eildal, Jonas N. N, Hultqvist, Greta, Balle, Thomas, Stuhr-Hansen, Nicolai, Padrah, Shahrokh, Gianni, Stefano, Strømgaard, Kristian, Jemth, Per
Published in Journal of the American Chemical Society (04.09.2013)
Published in Journal of the American Chemical Society (04.09.2013)
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Journal Article
Quantitative Toxicity Prediction via Meta Ensembling of Multitask Deep Learning Models
Karim, Abdul, Riahi, Vahid, Mishra, Avinash, Newton, M. A. Hakim, Dehzangi, Abdollah, Balle, Thomas, Sattar, Abdul
Published in ACS omega (11.05.2021)
Published in ACS omega (11.05.2021)
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Journal Article
Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State
Indurthi, Dinesh C, Lewis, Trevor M, Ahring, Philip K, Balle, Thomas, Chebib, Mary, Absalom, Nathan L
Published in PloS one (23.08.2016)
Published in PloS one (23.08.2016)
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Journal Article
Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHβE suggests a unique mode of antagonism
Shahsavar, Azadeh, Kastrup, Jette S, Nielsen, Elsebet Ø, Kristensen, Jesper L, Gajhede, Michael, Balle, Thomas
Published in PloS one (22.08.2012)
Published in PloS one (22.08.2012)
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Journal Article
Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders
Kowal, Natalia, Indurthi, Dinesh, Ahring, Philip, Chebib, Mary, Olafsdottir, Elin, Balle, Thomas
Published in Molecules (Basel, Switzerland) (27.01.2019)
Published in Molecules (Basel, Switzerland) (27.01.2019)
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Journal Article
GABAA receptor partial agonists and antagonists: structure, binding mode, and pharmacology
Krall, Jacob, Balle, Thomas, Krogsgaard-Larsen, Niels, Sørensen, Troels E, Krogsgaard-Larsen, Povl, Kristiansen, Uffe, Frølund, Bente
Published in Advances in pharmacology (1990) (2015)
Published in Advances in pharmacology (1990) (2015)
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Journal Article
Covalent Trapping of Methyllycaconitine at the α4-α4 Interface of the α4β2 Nicotinic Acetylcholine Receptor
Absalom, Nathan L., Quek, Gracia, Lewis, Trevor M., Qudah, Taima, von Arenstorff, Ida, Ambrus, Joseph I., Harpsøe, Kasper, Karim, Nasiara, Balle, Thomas, Mcleod, Malcolm D., Chebib, Mary
Published in The Journal of biological chemistry (01.09.2013)
Published in The Journal of biological chemistry (01.09.2013)
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Journal Article
Discovery of a Novel Allosteric Modulator of 5-HT3 Receptors
Trattnig, Sarah M., Harpsøe, Kasper, Thygesen, Sarah B., Rahr, Louise M., Ahring, Philip K., Balle, Thomas, Jensen, Anders A.
Published in The Journal of biological chemistry (01.07.2012)
Published in The Journal of biological chemistry (01.07.2012)
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