Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
Michalon, Aubin, Sidorov, Michael, Ballard, Theresa M., Ozmen, Laurence, Spooren, Will, Wettstein, Joseph G., Jaeschke, Georg, Bear, Mark F., Lindemann, Lothar
Published in Neuron (Cambridge, Mass.) (12.04.2012)
Published in Neuron (Cambridge, Mass.) (12.04.2012)
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Journal Article
Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats
Kohli, Shivali, King, Madeleine V, Williams, Stuart, Edwards, Adele, Ballard, Theresa M, Steward, Lucinda J, Alberati, Daniella, Fone, Kevin C F
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2019)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2019)
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Cognitive impairment in major depression and the mGlu2 receptor as a therapeutic target
Goeldner, Celia, Ballard, Theresa M., Knoflach, Frederic, Wichmann, Juergen, Gatti, Silvia, Umbricht, Daniel
Published in Neuropharmacology (01.01.2013)
Published in Neuropharmacology (01.01.2013)
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Journal Article
Chronic Metabotropic Glutamate Receptor 5 Inhibition Corrects Local Alterations of Brain Activity and Improves Cognitive Performance in Fragile X Mice
Michalon, Aubin, Bruns, Andreas, Risterucci, Céline, Honer, Michael, Ballard, Theresa M, Ozmen, Laurence, Jaeschke, Georg, Wettstein, Joseph G, von Kienlin, Markus, Künnecke, Basil, Lindemann, Lothar
Published in Biological psychiatry (1969) (01.02.2014)
Published in Biological psychiatry (1969) (01.02.2014)
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Journal Article
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
Hipp, Joerg F., Knoflach, Frederic, Comley, Robert, Ballard, Theresa M., Honer, Michael, Trube, Gerhard, Gasser, Rodolfo, Prinssen, Eric, Wallace, Tanya L., Rothfuss, Andreas, Knust, Henner, Lennon-Chrimes, Sian, Derks, Michael, Bentley, Darren, Squassante, Lisa, Nave, Stephane, Nöldeke, Jana, Wandel, Christoph, Thomas, Andrew W., Hernandez, Maria-Clemencia
Published in Scientific reports (08.04.2021)
Published in Scientific reports (08.04.2021)
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Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity
Porter, Richard H P, Jaeschke, Georg, Spooren, Will, Ballard, Theresa M, Büttelmann, Bernd, Kolczewski, Sabine, Peters, Jens-Uwe, Prinssen, Eric, Wichmann, Jürgen, Vieira, Eric, Mühlemann, Andreas, Gatti, Silvia, Mutel, Vincent, Malherbe, Pari
Published in The Journal of pharmacology and experimental therapeutics (01.11.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2005)
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Journal Article
Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent
Higgins, Guy A., Ballard, Theresa M., Kew, James N.C., Grayson Richards, J., Kemp, John A., Adam, Geo, Woltering, Thomas, Nakanishi, Shigetada, Mutel, Vincent
Published in Neuropharmacology (01.06.2004)
Published in Neuropharmacology (01.06.2004)
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Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety
Martin, James R, Ballard, Theresa M, Higgins, Guy A
Published in Pharmacology, biochemistry and behavior (01.04.2002)
Published in Pharmacology, biochemistry and behavior (01.04.2002)
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Journal Article
Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity
Ballard, Theresa M, Pauly-Evers, Meike, Higgins, Guy A, Ouagazzal, Abdel-Mouttalib, Mutel, Vincent, Borroni, Edilio, Kemp, John A, Bluethmann, Horst, Kew, James N. C
Published in The Journal of neuroscience (01.08.2002)
Published in The Journal of neuroscience (01.08.2002)
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Discovery of the imidazo[1,5-α][1,2,4].triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series
ACHERMANN, Guido, BALLARD, Theresa M, KOBLET, Andreas, KNUST, Henner, KURT, Anke, MARTIN, James R, MASCIADRI, Raffaello, PORTER, Richard H. P, STADLER, Heinz, THOMAS, Andrew W, TRUBE, Gerhard, WICHMANN, Jürgen, BLASCO, Francesca, BROUTIN, Pierre-Emmanuel, BÜTTELMANN, Bernd, FISCHER, Holger, GRAF, Martin, HERNANDEZ, Maria-Clemencia, HILTY, Peter, KNOFLACH, Frédéric
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Journal Article
Drug targets for cognitive enhancement in neuropsychiatric disorders
Wallace, Tanya L., Ballard, Theresa M., Pouzet, Bruno, Riedel, Wim J., Wettstein, Joseph G.
Published in Pharmacology, biochemistry and behavior (01.08.2011)
Published in Pharmacology, biochemistry and behavior (01.08.2011)
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The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia
Janhunen, Sanna K., Svärd, Heta, Talpos, John, Kumar, Gaurav, Steckler, Thomas, Plath, Niels, Lerdrup, Linda, Ruby, Trine, Haman, Marie, Wyler, Roger, Ballard, Theresa M.
Published in Psychopharmacology (01.11.2015)
Published in Psychopharmacology (01.11.2015)
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Journal Article
Book Review
Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists
Hoffmann, Torsten, Bös, Michael, Stadler, Heinz, Schnider, Patrick, Hunkeler, Walter, Godel, Thierry, Galley, Guido, Ballard, Theresa M., Higgins, Guy A., Poli, Sonia M., Sleight, Andrew J.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Journal Article
Tachykinin neurokinin 3 receptor antagonists: a patent review (2005 - 2010)
Malherbe, Pari, Ballard, Theresa M, Ratni, Hassen
Published in Expert opinion on therapeutic patents (01.05.2011)
Published in Expert opinion on therapeutic patents (01.05.2011)
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Synthesis and characterization of 1,3-dihydro-benzo[ b][1,4]diazepin-2-one derivatives: Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists
Woltering, Thomas J., Wichmann, Jürgen, Goetschi, Erwin, Knoflach, Frédéric, Ballard, Theresa M., Huwyler, Jörg, Gatti, Silvia
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
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Journal Article
The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats
McIntosh, Allison L., Ballard, Theresa M., Steward, Lucinda J., Moran, Paula M., Fone, Kevin C. F.
Published in Psychopharmacology (01.07.2013)
Published in Psychopharmacology (01.07.2013)
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Journal Article
RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors
Ballard, Theresa M., Knoflach, Frédéric, Prinssen, Eric, Borroni, Edilio, Vivian, Jeffrey A., Basile, Jennifer, Gasser, Rodolfo, Moreau, Jean-Luc, Wettstein, Joseph G., Buettelmann, Bernd, Knust, Henner, Thomas, Andrew W., Trube, Gerhard, Hernandez, Maria-Clemencia
Published in Psychopharmacology (01.01.2009)
Published in Psychopharmacology (01.01.2009)
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