Long-Term Safety and Efficacy of Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy: Interim Results of the PIONEER-OLE Study
Masri, Ahmad, Lester, Steven J, Stendahl, John C, Hegde, Sheila M, Sehnert, Amy J, Balaratnam, Ganesh, Shah, Ashish, Fox, Shawna, Wang, Andrew
Published in Journal of the American Heart Association (16.04.2024)
Published in Journal of the American Heart Association (16.04.2024)
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Antiviral Activity, Safety, and Pharmacokinetics of AL-794, a Novel Oral Influenza Endonuclease Inhibitor: Results of an Influenza Human Challenge Study
Yogaratnam, Jeysen, Rito, Jennifer, Kakuda, Thomas N, Fennema, Hein, Gupta, Kusum, Jekle, C Andreas, Mitchell, Toni, Boyce, Malcolm, Sahgal, Omair, Balaratnam, Ganesh, Chanda, Sushmita, Van Remoortere, Pieter, Symons, Julian A, Fry, John
Published in The Journal of infectious diseases (07.01.2019)
Published in The Journal of infectious diseases (07.01.2019)
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A Tool for Investigating Asthma and COPD Exacerbations: A Newly Manufactured and Well Characterised GMP Wild-Type Human Rhinovirus for Use in the Human Viral Challenge Model
Fullen, Daniel J, Murray, Bryan, Mori, Julie, Catchpole, Andrew, Borley, Daryl W, Murray, Edward J, Balaratnam, Ganesh, Gilbert, Anthony, Mann, Alex, Hughes, Fiona, Lambkin-Williams, Rob
Published in PloS one (09.12.2016)
Published in PloS one (09.12.2016)
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Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model
Fullen, Daniel J, Noulin, Nicolas, Catchpole, Andrew, Fathi, Hosnieh, Murray, Edward J, Mann, Alex, Eze, Kingsley, Balaratnam, Ganesh, Borley, Daryl W, Gilbert, Anthony, Lambkin-Williams, Rob
Published in PloS one (13.01.2016)
Published in PloS one (13.01.2016)
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Correction: Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model
Fullen, Daniel J, Noulin, Nicolas, Catchpole, Andrew, Fathi, Hosnieh, Murray, Edward J, Mann, Alex, Eze, Kingsley, Balaratnam, Ganesh, Borley, Daryl W, Gilbert, Anthony, Lambkin-Williams, Rob
Published in PloS one (09.06.2016)
Published in PloS one (09.06.2016)
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LONG-TERM SAFETY AND EFFICACY OF MAVACAMTEN IN PATIENTS (PTS) WITH SYMPTOMATIC OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (HCM): UPDATED RESULTS FROM THE PIONEER-OLE STUDY
Masri, Ahmad, Lester, Steven J., Stendahl, John, Hegde, Sheila M., Sehnert, Amy, Balaratnam, Ganesh, Fox, Shawna, Wang, Andrew
Published in Journal of the American College of Cardiology (07.03.2023)
Published in Journal of the American College of Cardiology (07.03.2023)
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Efficacy and Safety of Treatment With an Anti-M2e Monoclonal Antibody in Experimental Human Influenza
Ramos, Eleanor L., Mitcham, Jennifer L., Koller, Teri D., Bonavia, Aurelio, Usner, Dale W., Balaratnam, Ganesh, Fredlund, Paul, Swiderek, Kristine M.
Published in The Journal of infectious diseases (01.04.2015)
Published in The Journal of infectious diseases (01.04.2015)
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Cumulative long-term efficacy and safety of mavacamten treatment in nonobstructive hypertrophic cardiomyopathy: updated interim analysis from the MAVERICK cohort of the MAVA-long-term extension (LTE) study up to 120 weeks
Owens, Anjali, Sherrid, Mark, Rader, Florian, Wong, Timothy, Wever-Pinzon, Omar, Choudhury, Lubna, Fox, Shawna, Shah, Ashish, Balaratnam, Ganesh, Masri, Ahmad
Published in Journal of cardiac failure (01.01.2024)
Published in Journal of cardiac failure (01.01.2024)
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Design of DISCOVER-HCM: A Registry of Real-world Treatment Patterns and Outcomes of Patients with Symptomatic Obstructive Hypertrophic Cardiomyopathy
Hernandez, Adrian, Masoudi, Frederick, Mazimba, Sula, Saberi, Sara, Setoguchi, Soko, Spertus, John, Shen, Sophie, Balaratnam, Ganesh, Chen, Yu-mao, Afsari, Sonia, Minton, Neil, Januzzi, James
Published in Journal of cardiac failure (01.01.2024)
Published in Journal of cardiac failure (01.01.2024)
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96-WEEK CARDIAC MAGNETIC RESONANCE (CMR) RESULTS OF TREATMENT WITH MAVACAMTEN FROM THE EXPLORER COHORT OF THE MAVA-LONG-TERM EXTENSION (LTE) STUDY IN PATIENTS (PTS) WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (HCM)
Saberi, Sara, Kramer, Christopher M., Oreziak, Artur, Masri, Ahmad, Villa, Roberto Barriales, Abraham, Theodore P., Lakdawala, Neal K., Wang, Andrew, Choudhury, Lubna, Rader, Florian, Hegde, Sheila M., Kwong, Raymond Y., Balaratnam, Ganesh, Kurio, Greg, Fox, Shawna, Olivotto, Iacopo, Owens, Anjali Tiku
Published in Journal of the American College of Cardiology (07.03.2023)
Published in Journal of the American College of Cardiology (07.03.2023)
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Long-term effect of mavacamten in obstructive hypertrophic cardiomyopathy
Garcia-Pavia, Pablo, Oręziak, Artur, Masri, Ahmad, Barriales-Villa, Roberto, Abraham, Theodore P, Owens, Anjali T, Jensen, Morten K, Wojakowski, Wojciech, Seidler, Tim, Hagege, Albert, Lakdawala, Neal K, Wang, Andrew, Wheeler, Matthew T, Choudhury, Lubna, Balaratnam, Ganesh, Shah, Ashish, Fox, Shawna, Hegde, Sheila M, Olivotto, Iacopo
Published in European heart journal (01.09.2024)
Published in European heart journal (01.09.2024)
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Journal Article
Abstract 9685: Long-Term Efficacy and Safety of Mavacamten in Patients with Non-Obstructive Hypertrophic Cardiomyopathy: Interim Results from the MAVERICK-LTE Cohort of the MAVA-LTE Study
Owens, Anjali, Sherrid, Mark V, Wong, Timothy C, Bach, Richard G, Wever-Pinzon, Omar, Rigolli, Marzia, Balaratnam, Ganesh, Ma, Grace, Mealiffe, Matthew E, Edelberg, Jay M, Lakdawala, Neal K, Masri, Ahmad, Wang, Andrew
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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A Synthetic Influenza Virus Vaccine Induces a Cellular Immune Response That Correlates with Reduction in Symptomatology and Virus Shedding in a Randomized Phase Ib Live-Virus Challenge in Humans
Pleguezuelos, Olga, Robinson, Stuart, Fernández, Ana, Stoloff, Gregory A, Mann, Alex, Gilbert, Anthony, Balaratnam, Ganesh, Wilkinson, Tom, Lambkin-Williams, Rob, Oxford, John, Caparrós-Wanderley, Wilson
Published in Clinical and vaccine immunology (01.07.2015)
Published in Clinical and vaccine immunology (01.07.2015)
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Mavacamten Treatment for Symptomatic Obstructive Hypertrophic Cardiomyopathy
Rader, Florian, Oręziak, Artur, Choudhury, Lubna, Saberi, Sara, Fermin, David, Wheeler, Matthew T., Abraham, Theodore P., Garcia-Pavia, Pablo, Zwas, Donna R., Masri, Ahmad, Owens, Anjali, Hegde, Sheila M., Seidler, Tim, Fox, Shawna, Balaratnam, Ganesh, Sehnert, Amy J., Olivotto, Iacopo
Published in JACC. Heart failure (01.01.2024)
Published in JACC. Heart failure (01.01.2024)
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Journal Article
LONG-TERM SAFETY OF MAVACAMTEN IN PATIENTS WITH OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: INTERIM RESULTS OF THE MAVA-LONG TERM EXTENSION (LTE) STUDY
Rader, Florian, Choudhury, Lubna, Saberi, Sara, Fermin, David, Wheeler, Matthew T., Abraham, Theodore P., Oreziak, Artur, Garcia-Pavia, Pablo, Zwas, Donna, Sehnert, Amy J., Balaratnam, Ganesh, Ma, Grace, Olivotto, Iacopo
Published in Journal of the American College of Cardiology (11.05.2021)
Published in Journal of the American College of Cardiology (11.05.2021)
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Viral Induced Disease in Mild Atopic Asthmatics: Dynamics of Pulmonary Function, Speed of Symptom Onset and Implications for Drug Intervention in HRV Inoculated Volunteers
Mann, Alex, Balaratnam, Ganesh, Gunter, Jane, Rucki, Pawel, Poll, Chris, Johnson, Martin, Lockett, Tony
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
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Journal Article
Mavacamten Treatment for Symptomatic Obstructive Hypertrophic Cardiomyopathy: Interim Results From the MAVA-LTE Study, EXPLORER-LTE Cohort
Rader, Florian, Oręziak, Artur, Choudhury, Lubna, Saberi, Sara, Fermin, David, Wheeler, Matthew T, Abraham, Theodore P, Garcia-Pavia, Pablo, Zwas, Donna R, Masri, Ahmad, Owens, Anjali, Hegde, Sheila M, Seidler, Tim, Fox, Shawna, Balaratnam, Ganesh, Sehnert, Amy J, Olivotto, Iacopo
Published in JACC. Heart failure (01.01.2024)
Published in JACC. Heart failure (01.01.2024)
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The Pharmacokinetics (PK) of GBT440 Following Single Doses in Pediatric Patients with Sickle Cell Disease (SCD)
Washington, Carla B, Green, Michelle, Inati, Adlette C., Brown, Clark, Hoppe, Carolyn C, Wang, Winfred, Balaratnam, Ganesh, Dixon, Sandra, Fong, Erica, Hutchaleelaha, Athiwat, Tonda, Margaret E, Lehrer, Josh
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Initial Results from a Cohort in a Phase 2a Study (GBT440-007) Evaluating Adolescents with Sickle Cell Disease Treated with Multiple Doses of GBT440, a HbS Polymerization Inhibitor
Hoppe, Carolyn C, Inati, Adlette C., Brown, Clark, Wang, Winfred, Gordeuk, Victor R., Liem, Robert, Woods, Gerald, Piccone, Connie M., Fong, Erica, Balaratnam, Ganesh, Dixon, Sandy, Tonda, Margaret E, Washington, Carla B, Yaron, Yifah, Lehrer, Josh
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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