From mechanisms of heart failure to clinical heart success
Bakkers, Jeroen, Bellin, Milena, Hmeljak, Julija, Karra, Ravi
Published in Disease models & mechanisms (01.05.2023)
Published in Disease models & mechanisms (01.05.2023)
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Cardiac regenerative capacity: an evolutionary afterthought?
Nguyen, Phong D., de Bakker, Dennis E. M., Bakkers, Jeroen
Published in Cellular and molecular life sciences : CMLS (01.06.2021)
Published in Cellular and molecular life sciences : CMLS (01.06.2021)
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Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration
Wu, Chi-Chung, Kruse, Fabian, Vasudevarao, Mohankrishna Dalvoy, Junker, Jan Philipp, Zebrowski, David C., Fischer, Kristin, Noël, Emily S., Grün, Dominic, Berezikov, Eugene, Engel, Felix B., van Oudenaarden, Alexander, Weidinger, Gilbert, Bakkers, Jeroen
Published in Developmental cell (11.01.2016)
Published in Developmental cell (11.01.2016)
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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
Honkoop, Hessel, de Bakker, Dennis Em, Aharonov, Alla, Kruse, Fabian, Shakked, Avraham, Nguyen, Phong D, de Heus, Cecilia, Garric, Laurence, Muraro, Mauro J, Shoffner, Adam, Tessadori, Federico, Peterson, Joshua Craiger, Noort, Wendy, Bertozzi, Alberto, Weidinger, Gilbert, Posthuma, George, Grün, Dominic, van der Laarse, Willem J, Klumperman, Judith, Jaspers, Richard T, Poss, Kenneth D, van Oudenaarden, Alexander, Tzahor, Eldad, Bakkers, Jeroen
Published in eLife (23.12.2019)
Published in eLife (23.12.2019)
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Pyridox(am)ine 5′-phosphate oxidase (PNPO) deficiency in zebrafish results in fatal seizures and metabolic aberrations
Ciapaite, Jolita, Albersen, Monique, Savelberg, Sanne M.C., Bosma, Marjolein, Tessadori, Federico, Gerrits, Johan, Lansu, Nico, Zwakenberg, Susan, Bakkers, Jeroen P.W., Zwartkruis, Fried J.T., van Haaften, Gijs, Jans, Judith J., Verhoeven-Duif, Nanda M.
Published in Biochimica et biophysica acta. Molecular basis of disease (01.03.2020)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.03.2020)
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Lifting the cloche: Jeroen Bakkers interviews Didier Stainier
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Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects
Solman, Maja, Blokzijl-Franke, Sasja, Piques, Florian, Yan, Chuan, Yang, Qiqi, Strullu, Marion, Kamel, Sarah M, Ak, Pakize, Bakkers, Jeroen, Langenau, David M, Cavé, Hélène, den Hertog, Jeroen
Published in eLife (10.05.2022)
Published in eLife (10.05.2022)
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GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay
Rumping, Lynne, Tessadori, Federico, Pouwels, Petra J W, Vringer, Esmee, Wijnen, Jannie P, Bhogal, Alex A, Savelberg, Sanne M C, Duran, Karen J, Bakkers, Mark J G, Ramos, Rúben J J, Schellekens, Peter A W, Kroes, Hester Y, Klomp, Dennis W J, Black, Graeme C M, Taylor, Rachel L, Bakkers, Jeroen P W, Prinsen, Hubertus C M T, van der Knaap, Marjo S, Dansen, Tobias B, Rehmann, Holger, Zwartkruis, Fried J T, Houwen, Roderick H J, van Haaften, Gijs, Verhoeven-Duif, Nanda M, Jans, Judith J M, van Hasselt, Peter M
Published in Human molecular genetics (01.01.2019)
Published in Human molecular genetics (01.01.2019)
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Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
Tessadori, Federico, Tsingos, Erika, Colizzi, Enrico Sandro, Kruse, Fabian, van den Brink, Susanne C, van den Boogaard, Malou, Christoffels, Vincent M, Merks, Roeland MH, Bakkers, Jeroen
Published in eLife (10.08.2021)
Published in eLife (10.08.2021)
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Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders
Tessadori, Federico, Roessler, Helen I, Savelberg, Sanne M C, Chocron, Sonja, Kamel, Sarah M, Duran, Karen J, van Haelst, Mieke M, van Haaften, Gijs, Bakkers, Jeroen
Published in Disease models & mechanisms (01.10.2018)
Published in Disease models & mechanisms (01.10.2018)
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Identification and functional characterization of cardiac pacemaker cells in zebrafish
Tessadori, Federico, van Weerd, Jan Hendrik, Burkhard, Silja B, Verkerk, Arie O, de Pater, Emma, Boukens, Bastiaan J, Vink, Aryan, Christoffels, Vincent M, Bakkers, Jeroen
Published in PloS one (16.10.2012)
Published in PloS one (16.10.2012)
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ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9
Smeland, Marie F., McClenaghan, Conor, Roessler, Helen I., Savelberg, Sanne, Hansen, Geir Åsmund Myge, Hjellnes, Helene, Arntzen, Kjell Arne, Müller, Kai Ivar, Dybesland, Andreas Rosenberger, Harter, Theresa, Sala-Rabanal, Monica, Emfinger, Chris H., Huang, Yan, Singareddy, Soma S., Gunn, Jamie, Wozniak, David F., Kovacs, Attila, Massink, Maarten, Tessadori, Federico, Kamel, Sarah M., Bakkers, Jeroen, Remedi, Maria S., Van Ghelue, Marijke, Nichols, Colin G., van Haaften, Gijs
Published in Nature communications (01.10.2019)
Published in Nature communications (01.10.2019)
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Macrophage development from HSCs requires PU.1-coordinated microRNA expression
Ghani, Saeed, Riemke, Pia, Schönheit, Jörg, Lenze, Dido, Stumm, Jürgen, Hoogenkamp, Maarten, Lagendijk, Anne, Heinz, Sven, Bonifer, Constanze, Bakkers, Jeroen, Abdelilah-Seyfried, Salim, Hummel, Michael, Rosenbauer, Frank
Published in Blood (25.08.2011)
Published in Blood (25.08.2011)
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Zebrafish Bmp4 regulates left–right asymmetry at two distinct developmental time points
Chocron, Sonja, Verhoeven, Manon C., Rentzsch, Fabian, Hammerschmidt, Matthias, Bakkers, Jeroen
Published in Developmental biology (15.05.2007)
Published in Developmental biology (15.05.2007)
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Germline mutations affecting the histone H4 core cause a developmental syndrome by altering DNA damage response and cell cycle control
Tessadori, Federico, Giltay, Jacques C, Hurst, Jane A, Massink, Maarten P, Duran, Karen, Vos, Harmjan R, van Es, Robert M, Scott, Richard H, van Gassen, Koen L I, Bakkers, Jeroen, van Haaften, Gijs
Published in Nature genetics (01.11.2017)
Published in Nature genetics (01.11.2017)
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