Identification and characterization of mGlu3 ligands using a high throughput FLIPR assay for detection of agonists, antagonists, and allosteric modulators
Pratt, Steven D, Mezler, Mario, Geneste, Hervé, Bakker, Margot H M, Hajduk, Philip J, Gopalakrishnan, Sujatha M
Published in Combinatorial chemistry & high throughput screening (01.08.2011)
Published in Combinatorial chemistry & high throughput screening (01.08.2011)
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Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease
Schmid, Benjamin, Holst, Bjørn, Clausen, Christian, Bahnassawy, Lamiaa, Reinhardt, Peter, Bakker, Margot H.M., Díaz-Guerra, Eva, Vicario, Carlos, Martino-Adami, Pamela V., Thoenes, Michaela, Ramirez, Alfredo, Fliessbach, Klaus, Grezella, Clara, Brüstle, Oliver, Peitz, Michael, Ebneth, Andreas, Cabrera-Socorro, Alfredo
Published in Stem cell research (01.04.2021)
Published in Stem cell research (01.04.2021)
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Investigating the Role of APOE Genotype in Human Microglia
Ulm, Brittany, Amin, Najaf, Bahnassawy, Lamiaa, Reinhardt, Peter, Curado, Marco Rocha, Peitz, Michael, Fliessbach, Klaus, Ramirez, Alfredo, Ruiz, Agustin, Ried, Janina S, Bakker, Margot H.M., Van Duijn, Cornelia M
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Cross‐omics studies of the role of apolipoprotein E in Alzheimer’s disease and dementia: Searching common pathways in patients, populations and cellular models: Alzheimer's disease apolipoprotein pathology for treatment elucidation and development: The adapted project results
van Duijn, Cornelia M., Ahmad, Shahzad, Sáez, María Eugenia, Bennett, Keiryn, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Ramirez, Alfredo, Ruiz, Agustín, Hankemeier, Thomas
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Cross‐omics studies of the role of apolipoprotein E in Alzheimer’s disease and dementia: Searching common pathways in patients, populations and cellular models
van Duijn, Cornelia M., Ahmad, Shahzad, Sáez, María Eugenia, Bennett, Keiryn, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Ramirez, Alfredo, Ruiz, Agustín, Hankemeier, Thomas
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Modelling AD‐relevant pathophysiology in neurons, astrocytes and microglia from two complete sets of isogenic iPSC lines generated by the ADAPTED project
Socorro, Alfredo Cabrera, Schmid, Benjamin, Clausen, Christian, Holst, Bjørn, Peitz, Michael, Grezella, Clara, Brustle, Oliver, Bahnassawy, Lamiaa, Bennett, Keiryn, Ried, Janina S., Sáez, María Eugenia, Ramaswamy, Gayathri, Ruiz, Agustin, Bakker, Margot H.M., Vicario, Carlos, Lourenco, Teresa Silva, Reinhardt, Peter
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Characterization of transcriptional and proteomics changes in brain cells derived from isogenic hiPSCs reveals cell type–and genotype‐specific mechanisms modified by APOE
Ried, Janina S., Curado, Marco Rocha, Sáez, María Eugenia, Bahnassawy, Lamiaa, Lee, Heyne, Reinhardt, Peter, Mohler, Eric G., Madrid, Laura, Socorro, Alfredo Cabrera, Grezella, Clara, Nicolas, Armel, Rao, Francesco, Ramaswamy, Gayathri, Bakker, Margot H.M.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Modelling AD‐relevant pathophysiology in neurons, astrocytes and microglia from two complete sets of isogenic iPSC lines generated by the ADAPTED project: Alzheimer's disease apolipoprotein pathology for treatment elucidation and development: The adapted project results
Socorro, Alfredo Cabrera, Schmid, Benjamin, Clausen, Christian, Holst, Bjørn, Peitz, Michael, Grezella, Clara, Brustle, Oliver, Bahnassawy, Lamiaa, Bennett, Keiryn, Ried, Janina S., Sáez, María Eugenia, Ramaswamy, Gayathri, Ruiz, Agustin, Bakker, Margot H.M., Vicario, Carlos, Lourenco, Teresa Silva, Reinhardt, Peter
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Characterization of transcriptional and proteomics changes in brain cells derived from isogenic hiPSCs reveals cell type–and genotype‐specific mechanisms modified by APOE: Alzheimer's disease apolipoprotein pathology for treatment elucidation and development: The adapted project results
Ried, Janina S., Curado, Marco Rocha, Sáez, María Eugenia, Bahnassawy, Lamiaa, Lee, Heyne, Reinhardt, Peter, Mohler, Eric G., Madrid, Laura, Socorro, Alfredo Cabrera, Grezella, Clara, Nicolas, Armel, Rao, Francesco, Ramaswamy, Gayathri, Bakker, Margot H.M.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Multilayer OMICS characterization of APOE‐modulated isogenic hiPSCs elucidates cell‐type–specific mechanisms modified by APOE: A study of the IMI ADAPTED Consortium: Genetics/omics and systems biology
Ried, Janina S., Curado, Marco Rocha, Sáez, María Eugenia, Bahnassawy, Lamiaa, Lee, Heyne, Reinhardt, Peter, Mohler, Eric G., Madrid, Laura, Socorro, Alfredo Cabrera, Grezella, Clara, Nicolas, Armel, Rao, Francesco, Ramaswamy, Gayathri, Bakker, Margot H.M.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Proteomic, metabolomic, and transcriptomic examination of APOE transgenic mice: Genetics/omics and systems biology
Mohler, Eric G., Ried, Janina S., Bahnassawy, Lamiaa, Reinhardt, Peter, Curado, Marco Rocha, Bakker, Margot H.M., Nicolas, Armel, Rao, Francesco, Kohler, Isabelle, Hankemeier, Thomas, Ramaswamy, Gayathri, Sáez, María Eugenia
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Multilayer OMICS characterization of APOE‐modulated isogenic hiPSCs elucidates cell‐type–specific mechanisms modified by APOE: A study of the IMI ADAPTED Consortium
Ried, Janina S., Curado, Marco Rocha, Sáez, María Eugenia, Bahnassawy, Lamiaa, Lee, Heyne, Reinhardt, Peter, Mohler, Eric G., Madrid, Laura, Socorro, Alfredo Cabrera, Grezella, Clara, Nicolas, Armel, Rao, Francesco, Ramaswamy, Gayathri, Bakker, Margot H.M.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Proteomic, metabolomic, and transcriptomic examination of APOE transgenic mice
Mohler, Eric G., Ried, Janina S., Bahnassawy, Lamiaa, Reinhardt, Peter, Curado, Marco Rocha, Bakker, Margot H.M., Nicolas, Armel, Rao, Francesco, Kohler, Isabelle, Hankemeier, Thomas, Ramaswamy, Gayathri, Sáez, María Eugenia
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
SYSTEMATIC APOE GENOTYPE-STRATIFIED ANALYSIS OF HUMAN OMICS DATA: A STUDY FROM THE IMI ADAPTED PROJECT
Madrid, Laura, Hernández-Olasagarre, Begoña, González-Pérez, Antonio, Ried, Janina S., Bakker, Margot H.M., Ruiz, Agustin, Sáez, María Eugenia
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Journal Article
P3‐139: SYSTEMATIC APOE GENOTYPE‐STRATIFIED ANALYSIS OF HUMAN OMICS DATA: A STUDY FROM THE IMI ADAPTED PROJECT
Madrid, Laura, Hernández-Olasagarre, Begoña, González-Pérez, Antonio, Ried, Janina S., Bakker, Margot H.M., Ruiz, Agustin, Sáez, María Eugenia
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Journal Article
Identification of APOE phenotypes in microglia and neurons derived from isogenic hips cells: A study of the IMI ADAPTED consortium
Bahnassawy, Lamiaa, Buchheit, Johanna, Curado, Marco Rocha, Ried, Janina S., Sáez, María Eugenia, Nicolas, Armel, Rao, Francesco, Kaplan, Charlotte, Mohler, Eric G., Lee, Heyne, Untucht, Christopher, Korffmann, Juergen, Lakics, Viktor, Cik, Miroslav, Grezella, Clara, Brustle, Oliver, Peitz, Michael, Mañes, Santos, Ramaswamy, Gayathri, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Reinhardt, Peter
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Identification of APOE phenotypes in microglia and neurons derived from isogenic hips cells: A study of the IMI ADAPTED consortium: Molecular and cell biology/stem cells, iPS cells
Bahnassawy, Lamiaa, Buchheit, Johanna, Curado, Marco Rocha, Ried, Janina S., Sáez, María Eugenia, Nicolas, Armel, Rao, Francesco, Kaplan, Charlotte, Mohler, Eric G., Lee, Heyne, Untucht, Christopher, Korffmann, Juergen, Lakics, Viktor, Cik, Miroslav, Grezella, Clara, Brustle, Oliver, Peitz, Michael, Mañes, Santos, Ramaswamy, Gayathri, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Reinhardt, Peter
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
P4‐057: MODELING ALZHEIMER'S DISEASE PATHOPHYSIOLOGY USING ISOGENIC HUMAN APOE IPSC‐DERIVED NEURAL CELLS
Bahnassawy, Lamiaa, Reinhardt, Peter, Korffmann, Juergen, Kiefer, Claudia, Cik, Miroslav, Mohler, Eric G., Ried, Janina S., Lakics, Viktor, Bakker, Margot H.M.
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Journal Article
CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers
Ahmad, Shahzad, Milan, Marta del Campo, Hansson, Oskar, Demirkan, Ayse, Agustin, Ruiz, Sáez, Maria E., Giagtzoglou, Nikolaos, Cabrera-Socorro, Alfredo, Bakker, Margot H. M., Ramirez, Alfredo, Hankemeier, Thomas, Stomrud, Erik, Mattsson-Carlgren, Niklas, Scheltens, Philip, van der Flier, Wiesje M., Ikram, M. Arfan, Malarstig, Anders, Teunissen, Charlotte E., Amin, Najaf, van Duijn, Cornelia M.
Published in Scientific reports (19.05.2020)
Published in Scientific reports (19.05.2020)
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CDH6 AND HAGH PROTEIN LEVELS IN PLASMA ASSOCIATE WITH ALZHEIMER’S DISEASE IN APOE ε4 CARRIERS
Ahmad, Shahzad, Del Campo, Marta, Demirkan, Ayşe, Ruiz, Agustín, Sáez, María Eugenia, Giagtzoglou, Nikolaos, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Hankemeier, Thomas, van der Flier, Wiesje M., Ikram, M. Arfan, Teunissen, Charlotte E., Amin, Najaf, van Duijn, Cornelia M.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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