Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling
Bridges, Richard, Lutgen, Victoria, Lobner, Doug, Baker, David A
Published in Pharmacological reviews (01.07.2012)
Published in Pharmacological reviews (01.07.2012)
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Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck
Braun, Katarina M, Moreno, Gage K, Halfmann, Peter J, Hodcroft, Emma B, Baker, David A, Boehm, Emma C, Weiler, Andrea M, Haj, Amelia K, Hatta, Masato, Chiba, Shiho, Maemura, Tadashi, Kawaoka, Yoshihiro, Koelle, Katia, O'Connor, David H, Friedrich, Thomas C
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
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The landscape of antibody binding in SARS-CoV-2 infection
Heffron, Anna S, McIlwain, Sean J, Amjadi, Maya F, Baker, David A, Khullar, Saniya, Armbrust, Tammy, Halfmann, Peter J, Kawaoka, Yoshihiro, Sethi, Ajay K, Palmenberg, Ann C, Shelef, Miriam A, O'Connor, David H, Ong, Irene M
Published in PLoS biology (18.06.2021)
Published in PLoS biology (18.06.2021)
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A transcriptional switch underlies commitment to sexual development in malaria parasites
Kafsack, Björn F C, Rovira-Graells, Núria, Clark, Taane G, Bancells, Cristina, Crowley, Valerie M, Campino, Susana G, Williams, April E, Drought, Laura G, Kwiatkowski, Dominic P, Baker, David A, Cortés, Alfred, Llinás, Manuel
Published in Nature (London) (13.03.2014)
Published in Nature (London) (13.03.2014)
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Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress
Collins, Christine R, Hackett, Fiona, Strath, Malcolm, Penzo, Maria, Withers-Martinez, Chrislaine, Baker, David A, Blackman, Michael J
Published in PLoS pathogens (01.05.2013)
Published in PLoS pathogens (01.05.2013)
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Antimalarial activity of primaquine operates via a two-step biochemical relay
Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard S, Saif, Ahmed, March, Sandra, Wong, Michael H L, Leung, Suet, Miller, Alex B, Baker, David A, Alano, Pietro, Paine, Mark J I, Bhatia, Sangeeta N, O'Neill, Paul M, Ward, Stephen A, Biagini, Giancarlo A
Published in Nature communications (19.07.2019)
Published in Nature communications (19.07.2019)
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Acute SARS-CoV-2 infections harbor limited within-host diversity and transmit via tight transmission bottlenecks
Braun, Katarina M, Moreno, Gage K, Wagner, Cassia, Accola, Molly A, Rehrauer, William M, Baker, David A, Koelle, Katia, O'Connor, David H, Bedford, Trevor, Friedrich, Thomas C, Moncla, Louise H
Published in PLoS pathogens (23.08.2021)
Published in PLoS pathogens (23.08.2021)
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Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
Swaminathan, Vinay, Kalappurakkal, Joseph Mathew, Mehta, Shalin B., Nordenfelt, Pontus, Moore, Travis I., Koga, Nobuyasu, Baker, David A., Oldenbourg, Rudolf, Tani, Tomomi, Mayor, Satyajit, Springer, Timothy A., Waterman, Clare M.
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2017)
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Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery
Patel, Avnish, Perrin, Abigail J, Flynn, Helen R, Bisson, Claudine, Withers-Martinez, Chrislaine, Treeck, Moritz, Flueck, Christian, Nicastro, Giuseppe, Martin, Stephen R, Ramos, Andres, Gilberger, Tim W, Snijders, Ambrosius P, Blackman, Michael J, Baker, David A
Published in PLoS biology (10.05.2019)
Published in PLoS biology (10.05.2019)
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Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites
Koussis, Konstantinos, Haase, Silvia, Withers-Martinez, Chrislaine, Flynn, Helen R, Kunzelmann, Simone, Christodoulou, Evangelos, Ibrahim, Fairouz, Skehel, Mark, Baker, David A, Blackman, Michael J
Published in PLoS pathogens (27.06.2024)
Published in PLoS pathogens (27.06.2024)
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In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6
Takashita, Emi, Yamayoshi, Seiya, Halfmann, Peter, Wilson, Nancy, Ries, Hunter, Richardson, Alex, Bobholz, Max, Vuyk, William, Maddox, Robert, Baker, David A., Friedrich, Thomas C., O’Connor, David H., Uraki, Ryuta, Ito, Mutsumi, Sakai-Tagawa, Yuko, Adachi, Eisuke, Saito, Makoto, Koga, Michiko, Tsutsumi, Takeya, Iwatsuki-Horimoto, Kiyoko, Kiso, Maki, Yotsuyanagi, Hiroshi, Watanabe, Shinji, Hasegawa, Hideki, Imai, Masaki, Kawaoka, Yoshihiro
Published in New England Journal of Medicine (01.12.2022)
Published in New England Journal of Medicine (01.12.2022)
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Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites
Ressurreição, Margarida, Thomas, James A, Nofal, Stephanie D, Flueck, Christian, Moon, Robert W, Baker, David A, van Ooij, Christiaan
Published in PloS one (16.07.2020)
Published in PloS one (16.07.2020)
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Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex
McReynolds, Jayme R., Doncheck, Elizabeth M., Li, Yan, Vranjkovic, Oliver, Graf, Evan N., Ogasawara, Daisuke, Cravatt, Benjamin F., Baker, David A., Liu, Qing-Song, Hillard, Cecilia J., Mantsch, John R.
Published in Biological psychiatry (1969) (15.07.2018)
Published in Biological psychiatry (1969) (15.07.2018)
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Plasmodium falciparum Guanylyl Cyclase-Alpha and the Activity of Its Appended P4-ATPase Domain Are Essential for cGMP Synthesis and Blood-Stage Egress
Nofal, Stephanie D, Patel, Avnish, Blackman, Michael J, Flueck, Christian, Baker, David A
Published in mBio (26.01.2021)
Published in mBio (26.01.2021)
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Targeting the Malaria Parasite cGMP-Dependent Protein Kinase to Develop New Drugs
Baker, David A, Matralis, Alexios N, Osborne, Simon A, Large, Jonathan M, Penzo, Maria
Published in Frontiers in microbiology (17.12.2020)
Published in Frontiers in microbiology (17.12.2020)
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CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation
Patel, Avnish, Nofal, Stephanie D., Blackman, Michael J., Baker, David A.
Published in mBio (12.07.2022)
Published in mBio (12.07.2022)
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Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion
Flueck, Christian, Drought, Laura G, Jones, Andrew, Patel, Avnish, Perrin, Abigail J, Walker, Eloise M, Nofal, Stephanie D, Snijders, Ambrosius P, Blackman, Michael J, Baker, David A
Published in PLoS biology (22.02.2019)
Published in PLoS biology (22.02.2019)
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Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
Mohring, Franziska, Hart, Melissa Natalie, Rawlinson, Thomas A, Henrici, Ryan, Charleston, James A, Diez Benavente, Ernest, Patel, Avnish, Hall, Joanna, Almond, Neil, Campino, Susana, Clark, Taane G, Sutherland, Colin J, Baker, David A, Draper, Simon J, Moon, Robert William
Published in eLife (17.06.2019)
Published in eLife (17.06.2019)
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