Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase
Shih, I-Hung, Vliegen, Inge, Peng, Betty, Yang, Huiling, Hebner, Christy, Paeshuyse, Jan, Pürstinger, Gerhard, Fenaux, Martijn, Tian, Yang, Mabery, Eric, Qi, Xiaoping, Bahador, Gina, Paulson, Matthew, Lehman, Laura S, Bondy, Steven, Tse, Winston, Reiser, Hans, Lee, William A, Schmitz, Uli, Neyts, Johan, Zhong, Weidong
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
Get full text
Journal Article
Highly Functionalized and Potent Antiviral Cyclopentane Derivatives Formed by a Tandem Process Consisting of Organometallic, Transition-Metal-Catalyzed, and Radical Reaction Steps
Jagtap, Pratap R., Ford, Leigh, Deister, Elmar, Pohl, Radek, Císařová, Ivana, Hodek, Jan, Weber, Jan, Mackman, Richard, Bahador, Gina, Jahn, Ullrich
Published in Chemistry : a European journal (11.08.2014)
Published in Chemistry : a European journal (11.08.2014)
Get full text
Journal Article
Selection of Clinically Relevant Protease Inhibitor-Resistant Viruses Using the Genotype 2a Hepatitis C Virus Infection System
GUOFENG CHENG, KATIE CHAN, HUILING YANG, CORSA, Amy, POKROVSKII, Maria, PAULSON, Matthew, BAHADOR, Gina, WEIDONG ZHONG, DELANEY IV, William
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Get full text
Journal Article
Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines
Perlíková, Pavla, Eberlin, Ludovic, Ménová, Petra, Raindlová, Veronika, Slavětínská, Lenka, Tloušťová, Eva, Bahador, Gina, Lee, Yu-Jen, Hocek, Michal
Published in ChemMedChem (01.05.2013)
Published in ChemMedChem (01.05.2013)
Get full text
Journal Article
Lithium Chloride Catalyzed Asymmetric Domino Aza-Michael Addition/[3+2] Cycloaddition Reactions for the Synthesis of Spiro- and Bicyclic ,,-Triamino Acid Derivatives
Just, David, Hernandez-Guerra, Daniel, Kritsch, Susanne, Pohl, Radek, Cisarova, Ivana, Jones, Peter G., Mackman, Richard, Bahador, Gina, Jahn, Ullrich
Published in European journal of organic chemistry (09.10.2018)
Published in European journal of organic chemistry (09.10.2018)
Get full text
Journal Article
N,2,3,4-Tetrasubstituted Pyrrolidines through Tandem Lithium Amide Conjugate Addition/Radical Cyclization/Oxygenation Reactions
Kafka, František, Pohl, Radek, Císařová, Ivana, Mackman, Richard, Bahador, Gina, Jahn, Ullrich
Published in European journal of organic chemistry (01.08.2016)
Published in European journal of organic chemistry (01.08.2016)
Get full text
Journal Article
Lithium Chloride Catalyzed Asymmetric Domino Aza‐Michael Addition/[3 + 2] Cycloaddition Reactions for the Synthesis of Spiro‐ and Bicyclic α,β,γ‐Triamino Acid Derivatives
Just, David, Hernandez‐Guerra, Daniel, Kritsch, Susanne, Pohl, Radek, Císařová, Ivana, Jones, Peter G., Mackman, Richard, Bahador, Gina, Jahn, Ullrich
Published in European journal of organic chemistry (09.10.2018)
Published in European journal of organic chemistry (09.10.2018)
Get full text
Journal Article
Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides
Tichý, Michal, Pohl, Radek, Tloušt’ová, Eva, Weber, Jan, Bahador, Gina, Lee, Yu-Jen, Hocek, Michal
Published in Bioorganic & medicinal chemistry (01.09.2013)
Published in Bioorganic & medicinal chemistry (01.09.2013)
Get full text
Journal Article
A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities
Jansa, Petr, Baszczyňski, Ondřej, Dračínský, Martin, Votruba, Ivan, Zídek, Zdeněk, Bahador, Gina, Stepan, George, Cihlar, Tomas, Mackman, Richard, Holý, Antonín, Janeba, Zlatko
Published in European journal of medicinal chemistry (01.09.2011)
Published in European journal of medicinal chemistry (01.09.2011)
Get full text
Journal Article
Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides
Nauš, Petr, Perlíková, Pavla, Bourderioux, Aurelie, Pohl, Radek, Slavětínská, Lenka, Votruba, Ivan, Bahador, Gina, Birkuš, Gabriel, Cihlář, Tomáš, Hocek, Michal
Published in Bioorganic & medicinal chemistry (01.09.2012)
Published in Bioorganic & medicinal chemistry (01.09.2012)
Get full text
Journal Article
Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2a2-C-methylribonucleosides, 2a2-deoxy-2a2-fluoroarabinonucleosides, arabinonucleosides and 2a2-deoxyribonucleosides
Naus, Petr, Perlikova, Pavla, Bourderioux, Aurelie, Pohl, Radek, Slavtinska, Lenka, Votruba, Ivan, Bahador, Gina, Birkus, Gabriel, Cihlac, Tomas, Hocek, Michal
Published in Bioorganic & medicinal chemistry (01.09.2012)
Published in Bioorganic & medicinal chemistry (01.09.2012)
Get full text
Journal Article
Selection of Clinically-relevant Protease Inhibitor Resistant Viruses using the HCV Infection System
Cheng, Guofeng, Chan, Katie, Yang, Huiling, Corsa, Amy, Pokrovskii, Maria, Paulson, Matthew, Robinson, Margaret, Bahador, Gina, Zhong, Weidong, Delaney, William
Published in Antiviral research (01.04.2010)
Published in Antiviral research (01.04.2010)
Get full text
Journal Article
SAR studies on dihydropyrimidinone antibiotics
Xu, Lianhong, Zhang, Lijun, Jones, Robert, Bryant, Clifford, Boddeker, Nina, Mabery, Eric, Bahador, Gina, Watson, Julia, Clough, Jeffery, Arimilli, Murty, Gillette, Wendy, Colagiovanni, Dorothy, Wang, Keyu, Gibbs, Craig, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Get full text
Journal Article
Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors
Lazerwith, Scott E, Bahador, Gina, Canales, Eda, Cheng, Guofeng, Chong, Lee, Clarke, Michael O, Doerffler, Edward, Eisenberg, Eugene J, Hayes, Jaclyn, Lu, Bing, Liu, Qi, Matles, Mike, Mertzman, Michael, Mitchell, Michael L, Morganelli, Philip, Murray, Bernard P, Robinson, Margaret, Strickley, Robert G, Tessler, Megan, Tirunagari, Neeraj, Wang, Jianhong, Wang, Yujin, Zhang, Jennifer R, Zheng, Xubin, Zhong, Weidong, Watkins, William J
Published in ACS medicinal chemistry letters (13.10.2011)
Published in ACS medicinal chemistry letters (13.10.2011)
Get full text
Journal Article
Characterization of a novel antibacterial agent that inhibits bacterial translation
BÖDDEKER, NINA, BAHADOR, GINA, GIBBS, CRAIG, MABERY, ERIC, WOLF, JOHN, XU, LIANHONG, WATSON, JULIA
Published in RNA (Cambridge) (01.09.2002)
Published in RNA (Cambridge) (01.09.2002)
Get full text
Journal Article
ChemInform Abstract: Highly Functionalized and Potent Antiviral Cyclopentane Derivatives Formed by a Tandem Process Consisting of Organometallic, Transition-Metal-Catalyzed, and Radical Reaction Steps
Jagtap, Pratap R., Ford, Leigh, Deister, Elmar, Pohl, Radek, Cisarova, Ivana, Hodek, Jan, Weber, Jan, Mackman, Richard, Bahador, Gina, Jahn, Ullrich
Published in ChemInform (01.02.2015)
Published in ChemInform (01.02.2015)
Get full text
Journal Article
Methods for screening for antibiotics
WATSON; JULIA C, MOEHLE; CHARLES M, HERNANDEZ; VICTOR JAMES, BAHADOR; RITU GINA
Year of Publication 07.12.1999
Get full text
Year of Publication 07.12.1999
Patent