Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP)
Baratchian, Mehdi, Davis, Christopher A., Shimizu, Akira, Escors, David, Bagnéris, Claire, Barrett, Tracey, Collins, Mary K.
Published in The Journal of biological chemistry (01.04.2016)
Published in The Journal of biological chemistry (01.04.2016)
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Journal Article
Crystal Structure of a vFlip-IKKγ Complex: Insights into Viral Activation of the IKK Signalosome
Bagnéris, Claire, Ageichik, Alexander V., Cronin, Nora, Wallace, Bonnie, Collins, Mary, Boshoff, Chris, Waksman, Gabriel, Barrett, Tracey
Published in Molecular cell (06.06.2008)
Published in Molecular cell (06.06.2008)
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Kaposi's Sarcoma-Associated Herpesvirus vFLIP and Human T Cell Lymphotropic Virus Type 1 Tax Oncogenic Proteins Activate IκB Kinase Subunit γ by Different Mechanisms Independent of the Physiological Cytokine-Induced Pathways
Shimizu, Akira, Baratchian, Mehdi, Takeuchi, Yasu, Escors, David, Macdonald, Douglas, Barrett, Tracey, Bagneris, Claire, Collins, Mary, Noursadeghi, Mahdad
Published in Journal of Virology (01.07.2011)
Published in Journal of Virology (01.07.2011)
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Journal Article
Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing
McCusker, Emily C., Bagnéris, Claire, Naylor, Claire E., Cole, Ambrose R., D'Avanzo, Nazzareno, Nichols, Colin G., Wallace, B.A.
Published in Nature communications (02.10.2012)
Published in Nature communications (02.10.2012)
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Journal Article
Molecular basis of ion permeability in a voltage-gated sodium channel
Naylor, Claire E, Bagnéris, Claire, DeCaen, Paul G, Sula, Altin, Scaglione, Antonella, Clapham, David E, Wallace, BA
Published in The EMBO journal (15.04.2016)
Published in The EMBO journal (15.04.2016)
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Journal Article
Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism
Bagnéris, Claire, DeCaen, Paul G., Naylor, Claire E., Pryde, David C., Nobeli, Irene, Clapham, David E., Wallace, B. A.
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
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Journal Article
Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel
Ulmschneider, Martin B., Bagnéris, Claire, McCusker, Emily C., DeCaen, Paul G., Delling, Markus, Clapham, David E., Ulmschneider, Jakob P., Wallace, B. A.
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2013)
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Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition
Shyam, Mousumi, Verma, Harshita, Bhattacharje, Gourab, Mukherjee, Piyali, Singh, Samsher, Kamilya, Sujit, Jalani, Pushpendu, Das, Swetarka, Dasgupta, Arunava, Mondal, Abhishake, Das, Amit Kumar, Singh, Amit, Brucoli, Federico, Bagnéris, Claire, Dickman, Rachael, Basavanakatti, Vinay N, Naresh Babu, Patibandla, Sankaran, Vadivelan, Dev, Abhimanyu, Sinha, Barij Nayan, Bhakta, Sanjib, Jayaprakash, Venkatesan
Published in Journal of medicinal chemistry (13.01.2022)
Published in Journal of medicinal chemistry (13.01.2022)
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A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase
Muselmani, Wael, Kashif-Khan, Naail, Bagnéris, Claire, Santangelo, Rosalia, Williams, Mark A, Savva, Renos
Published in Viruses (01.06.2023)
Published in Viruses (01.06.2023)
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Journal Article
Mechanistic insights into the activation of the IKK kinase complex by the Kaposi’s sarcoma herpes virus oncoprotein vFLIP
Bagnéris, Claire, Senthil Kumar, Swathi L., Baratchian, Mehdi, Britt, Hannah M., Assafa, Tufa E., Thalassinos, Konstantinos, Collins, Mary K., Barrett, Tracey E.
Published in The Journal of biological chemistry (01.06.2022)
Published in The Journal of biological chemistry (01.06.2022)
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Journal Article
Quaternary Dynamics of αB-Crystallin as a Direct Consequence of Localised Tertiary Fluctuations in the C-Terminus
Baldwin, Andrew J., Hilton, Gillian R., Lioe, Hadi, Bagnéris, Claire, Benesch, Justin L.P., Kay, Lewis E.
Published in Journal of molecular biology (21.10.2011)
Published in Journal of molecular biology (21.10.2011)
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Journal Article
KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing
Lee, Hyunah, Patschull, Anathe O M, Bagnéris, Claire, Ryan, Hannah, Sanderson, Christopher M, Ebrahimi, Bahram, Nobeli, Irene, Barrett, Tracey E
Published in Nucleic acids research (05.05.2017)
Published in Nucleic acids research (05.05.2017)
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Journal Article
IKKγ-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection
Briggs, Louise C, Chan, A W Edith, Davis, Christopher A, Whitelock, Nicholas, Hotiana, Hajira A, Baratchian, Mehdi, Bagnéris, Claire, Selwood, David L, Collins, Mary K, Barrett, Tracey E
Published in Journal of virology (01.12.2017)
Published in Journal of virology (01.12.2017)
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Journal Article
The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes
Keep, Nicholas H, Cohen-Gonsaud, Martin, Barthe, Philippe, Bagnéris, Claire, Henderson, Brian, Ward, John, Roumestand, Christian
Published in Nature structural & molecular biology (01.03.2005)
Published in Nature structural & molecular biology (01.03.2005)
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Journal Article
Probing the Solution Structure of IκB Kinase (IKK) Subunit γ and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit β by EPR Spectroscopy
Bagnéris, Claire, Rogala, Kacper B., Baratchian, Mehdi, Zamfir, Vlad, Kunze, Micha B.A., Dagless, Selina, Pirker, Katharina F., Collins, Mary K., Hall, Benjamin A., Barrett, Tracey E., Kay, Christopher W.M.
Published in The Journal of biological chemistry (03.07.2015)
Published in The Journal of biological chemistry (03.07.2015)
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Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB-DNA complexes
Webster, Matthew P J, Jukes, Rachael, Zamfir, Vlad S, Kay, Christopher W M, Bagnéris, Claire, Barrett, Tracey
Published in Nucleic acids research (01.09.2012)
Published in Nucleic acids research (01.09.2012)
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