Type II JAK2 Inhibitor NVP-CHZ868 Is Active in Vivo Against JAK2-Dependent B-Cell Acute Lymphoblastic Leukemias (B-ALLs)
Li, Loretta S., Wu, Shuo-Chieh, Kopp, Nadja, Montero, Joan, Ryan, Jeremy, Chapuy, Bjoern, Van der Zwet, Jordy C., Layer, Jacob, Weigert, Oliver, Christie, Amanda L, Christodoulou, Alexandra N., Liu, Huiyun, Yoda, Akinori, Hofmann, Francesco, Baffert, Fabienne, Vangrevelinghe, Eric, Gaul, Christoph, Radimerski, Thomas, Letai, Anthony G., Weinstock, David M.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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JAK1/2 and Pan-Deacetylase Inhibitor Combination Therapy Yields Improved Efficacy in Preclinical Mouse Models of JAK2V617F-Driven Disease
EVROT, Emeline, EBEL, Nicolas, HOFMANN, Francesco, MURAKAMI, Masato, BAFFERT, Fabienne, RADIMERSKI, Thomas, ROMANET, Vincent, ROELLI, Claudia, ANDRAOS, Rita, ZHIYAN QIAN, DÖLEMEYER, Arno, DAMMASSA, Ernesta, STERKER, Dario, COZENS, Robert
Published in Clinical cancer research (15.11.2013)
Published in Clinical cancer research (15.11.2013)
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Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics
SINI, Patrizia, SAMARZIJA, Ivana, SETYONO-HAN, Buddy, WOOD, Jeanette, HYNES, Nancy E, BAFFERT, Fabienne, LITTLEWOOD-EVANS, Amanda, SCHNELL, Christian, THEUER, Andreas, CHRISTIAN, Sven, BOOS, Anja, HESS-STUMPP, Holger, FOEKENS, John A
Published in Cancer research (Chicago, Ill.) (01.03.2008)
Published in Cancer research (Chicago, Ill.) (01.03.2008)
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Phase lb study of buparlisib (BKM120) plus either paclitaxel (PTX) in advanced solid tumors (aST) or PTX plus trastuzumab (TZ) in HER2+ breast cancer (BC)
Cruz Zambrano, Cristina, Schuler, Martin H., Machiels, Jean-Pascal H., Hess, Dagmar, Paz-Ares, Luis, Awada, Ahmad, von Moos, Roger, Steeghs, Neeltje, Rodon Ahnert, Jordi, De Mesmaeker, Peggy, Richly, Heike, Herremans, Catherine, Joerger, Markus, Corral Jaime, Jesus, Alsina, Maria, Baffert, Fabienne, Demanse, David, Duval, Vincent, Morozov, Alex, Dirix, Luc
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Phase lb study of BEZ235 plus either paclitaxel (PTX) in advanced solid tumors (aST) or PTX plus trastuzumab (TZ) in HER2+ breast cancer (BC)
Rodon Ahnert, Jordi, Schuler, Martin H., Machiels, Jean-Pascal H., Hess, Dagmar, Paz-Ares, Luis, Awada, Ahmad, von Moos, Roger, Steeghs, Neeltje, Cruz Zambrano, Cristina, De Mesmaeker, Peggy, Richly, Heike, Herremans, Catherine, Joerger, Markus, Corral Jaime, Jesus, Alsina, Maria, Baffert, Fabienne, Demanse, David, Duval, Vincent, Morozov, Alex, Dirix, Luc
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors
Gerspacher, Marc, Furet, Pascal, Pissot-Soldermann, Carole, Gaul, Christoph, Holzer, Philipp, Vangrevelinghe, Eric, Lang, Marc, Erdmann, Dirk, Radimerski, Thomas, Regnier, Catherine H., Chene, Patrick, Pover, Alain De, Hofmann, Francesco, Baffert, Fabienne, Buhl, Thomas, Aichholz, Reiner, Blasco, Francesca, Endres, Ralf, Trappe, Jörg, Drueckes, Peter
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Novel, Potent and Selective JAK2 Inhibitors
Radimerski, Thomas, Baffert, Fabienne, Regnier, Catherine H., De Pover, Alain, Pissot, Carole, Gerspacher, Marc, Brueggen, Josef, Tavares, Gisele, Blasco, Francesca, Ledieu, David, Nolan, Lynda, Ruetz, Stephan, Chene, Patrick, Erdmann, Dirk, Drueckes, Peter, Furet, Pascal, Lang, Marc, Trappe, Joerg, Vangrevelinghe, Eric, Wartmann, Markus, Hofmann, Francesco
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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