Indole-3-piperazinyl derivatives: Novel chemical class of 5-HT6 receptor antagonists
Nirogi, Ramakrishna V.S., Deshpande, Amol D., Kambhampati, Ramasastri, Badange, Rajesh Kumar, Kota, Laxman, Daulatabad, Anand V., Shinde, Anil K., Ahmad, Ishtiyaque, Kandikere, Vishwottam, Jayarajan, Pradeep, Dubey, P.K.
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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무스카린 M1 수용체 양성 알로스테릭 조절제로서 치환된 아자사이클
NIROGI RAMAKRISHNA, SHINDE ANIL KARBHARI, MOHAMMED ABDUL RASHEED, PALACHARLA RAGHAVA CHOUDARY, BADANGE RAJESH KUMAR, JASTI VENKATESWARLU
Year of Publication 29.07.2020
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Year of Publication 29.07.2020
Patent
무스카린 M1 수용체 포지티브 알로스테릭 조절제
NIROGI RAMAKRISHNA, SHINDE ANIL KARBHARI, MOHAMMED ABDUL RASHEED, JAYARAJAN PRADEEP, BADANGE RAJESH KUMAR, BHYRAPUNENI GOPINADH, JASTI VENKATESWARLU
Year of Publication 08.04.2019
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Year of Publication 08.04.2019
Patent
순수한 5-HT6 수용체 길항제로서의 플루오로피페리딘 화합물
NIROGI RAMAKRISHNA, GOYAL VINOD KUMAR, BOJJA KUMAR, SHINDE ANIL KARBHARI, MOHAMMED ABDUL RASHEED, PANDEY SANTOSH KUMAR, BADANGE RAJESH KUMAR, THENTU JAGADEESH BABU, JASTI VENKATESWARLU
Year of Publication 03.03.2020
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Year of Publication 03.03.2020
Patent
0051 Samelisant, a H3 Receptor Inverse Agonist for the Potential Treatment of Excessive Daytime Sleepiness in Parkinson’s Disease
Nirogi, Ramakrishna, Benade, Vijay, Abraham, Renny, Thentu, Jagadeesh Babu, Petlu, Surendra, Pandey, Santosh Kumar, Badange, Rajesh Kumar, Bojja, Kumar, Subramanian, Ramkumar
Published in Sleep (New York, N.Y.) (29.05.2023)
Published in Sleep (New York, N.Y.) (29.05.2023)
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SUVN‐I7016031: A Novel M 1 ‐receptor Positive Allosteric Modulator (M 1 ‐PAM) for the treatment of Parkinson's Disease Associated Dementia
Grandhi, Venkata Ramalingayya, Ganuga, Narender, Medapati, Rajesh Babu, Tadiparthi, Jayaprakash, Jayarajan, Pradeep, Shinde, Anil K, Badange, Rajesh Kumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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SUVN‐I7016031: A Novel M1‐receptor Positive Allosteric Modulator (M1‐PAM) for the treatment of Parkinson's Disease Associated Dementia
Grandhi, Venkata Ramalingayya, Ganuga, Narender, Medapati, Rajesh Babu, Tadiparthi, Jayaprakash, Jayarajan, Pradeep, Shinde, Anil K, Badange, Rajesh Kumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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SUVN‐I6107: Efficacy and safety assessments of a true muscarinic M1‐positive allosteric modulator for the treatment of dementia
Abraham, Renny, Subramanian, Ramkumar, Grandhi, Venkata Ramalingayya, Muddana, NageswaraRao, Kamuju, Venkatesh, Badange, Rajesh Kumar, Reballi, Veena, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Discovery and Development of 1-[(2-Bromophenyl)sulfony1]-5methoxy-3-[(4-methyl-1-piperazinyl)methy1]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer's Disease
Nirogi, Ramakrishna, Shinde, Anil, Kambhampati, Rama Sastry, Mohammed, Abdul Rasheed, Saraf, Sangram Keshari, Mohammed, Abdul Rasheed, Saraf, Sangram Keshari, Badange, Rajesh Kumar, Bandyala, Thrinath Reddy, Bhatta, Venugopalarao, Bojja, Kumar, Reballi, Veena, Subramanian, Ramkumar, Benade, Vijay, Palacharla, Raghava Choudary, Bhyrapuneni, Gopinadh, Jayarajan, Pradeep, Goyal, Vinod, Jasti, Venkat
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
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0265 Samelisant (SUVN-G3031), a Histamine H3 Receptor Inverse Agonist in Animal Models of Narcolepsy
Benade, Vijay, Abraham, Renny, Palacharla, Raghava Chowdary, Thentu, Jagadeesh Babu, Petlu, Surendra, Mekala, Venkat Reddy, Pandey, Santosh Kumar, Badange, Rajesh Kumar, Bojja, Kumar, Reballi, Veena, Achanta, Pramod Kumar, Choudakari, Praveen kumar, Nirogi, Ramakrishna
Published in Sleep (New York, N.Y.) (25.05.2022)
Published in Sleep (New York, N.Y.) (25.05.2022)
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Masupirdine (SUVN‐502) for the Potential Treatment of Agitation in Patients with Dementia of the Alzheimer’s Type: Preliminary Efficacy and Phase‐3 Study Design
Nirogi, Ramakrishna, Abraham, Renny, Ravula, Jyothsna, Jetta, Satish, Benade, Vijay, Shinde, Anil K, Rasheed, Mohammed Abdul, Badange, Rajesh Kumar, Goyal, Vinod Kumar, Palacharla, Veera Raghava Chowdary, Subramanian, Ramkumar, Jayarajan, Pradeep
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
SUVN‐I6107: A True Positive Allosteric Modulator (PAM) at Muscarinic M1 Receptors for the Treatment of Cognitive Disorders
Palacharla, Veera Raghava Chowdary, Guduru, Naga Sai Soma Chandra Sekhar, Medapati, Rajesh Babu, Srirangavaram, Maheshwari, Grandhi, Venkata Ramalingayya, Ganuga, Narender, Badange, Rajesh Kumar, Nakka, Harish, Subramanian, Ramkumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Potential beneficial effects of masupirdine (SUVN‐502) on agitation/aggression and psychosis in patients with moderate Alzheimer's disease: Exploratory post hoc analyses
Nirogi, Ramakrishna, Jayarajan, Pradeep, Benade, Vijay, Shinde, Anil, Goyal, Vinod Kumar, Jetta, Satish, Ravula, Jyothsna, Abraham, Renny, Grandhi, Venkata Ramalingayya, Subramanian, Ramkumar, Pandey, Santosh Kumar, Badange, Rajesh Kumar, Mohammed, Abdul Rasheed, Jasti, Venkat, Ballard, Clive, Cummings, Jeffrey
Published in International journal of geriatric psychiatry (01.10.2022)
Published in International journal of geriatric psychiatry (01.10.2022)
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Discovery and Development of N-[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Active Histamine H-3 Receptor Inverse Agonist with Robust Wake-Promoting Activity
Nirogi, Ramakrishna, Shinde, Anil, Mohammed, Abdul Rasheed, Badange, Rajesh Kumar, Reballi, Veena, Bandyala, Thrinath Reddy, Saraf, Sangram Keshari, Bojja, Kumar, Manchineella, Sravanthi, Achanta, Pramod Kumar, Kandukuri, Kiran Kumar, Subramanian, Ramkumar, Benade, Vijay, Palacharla, Raghava Choudary, Jayarajan, Pradeep, Pandey, Santoshkumar, Jasti, Venkat
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
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Effects of Masupirdine (SUVN‐502) on Agitation/Aggression and Psychosis in Patients with Probable Alzheimer’s Disease: A Post Hoc Analysis
Nirogi, Ramakrishna, Jayarajan, Pradeep, Abraham, Renny, Tadiparthi, Jayaprakash, Benade, Vijay, Shinde, Anil K, Rasheed, Mohammed Abdul, Badange, Rajesh Kumar, Goyal, Vinod Kumar, Palacharla, Veera Raghava Chowdary, Ravulu, Jyothsna, Jetta, Satish, Subramanian, Ramkumar
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Effect of Concurrent Use of Memantine on The Efficacy of Masupirdine (SUVN‐502): A Post‐hoc Analysis of a Phase‐2 Randomized Placebo‐Controlled Study
Goyal, Vinod Kumar, Pandey, Santosh Kumar, Benade, Vijay, Shinde, Anil K, Rasheed, Mohammed Abdul, Badange, Rajesh Kumar, Palacharla, Veera Raghava Chowdary, Ravulu, Jyothsna, Jetta, Satish, Subramanian, Ramkumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Masupirdine (SUVN‐502) in combination with donepezil and memantine in moderate Alzheimer's disease: Effect of AD duration since diagnosis and patient’s age on efficacy endpoints
Nirogi, Ramakrishna, Shinde, Anil K, Benade, Vijay, Subramanian, Ramkumar, Bhyrapuneni, Gopinadh, Ravulu, Jyothsna, Jetta, Satish, Rasheed, Mohammed Abdul, Badange, Rajesh Kumar, Jasti, Venkat
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Masupirdine (SUVN‐502) in combination with donepezil and memantine in moderate Alzheimer's disease: Effect of AD duration since diagnosis and patient’s age on efficacy endpoints: Human/Human trials: Cognitive enhancement
Nirogi, Ramakrishna, Shinde, Anil K, Benade, Vijay, Subramanian, Ramkumar, Bhyrapuneni, Gopinadh, Ravulu, Jyothsna, Jetta, Satish, Rasheed, Mohammed Abdul, Badange, Rajesh Kumar, Jasti, Venkat
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Discovery and Development of 1‑[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]‑1H‑indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer’s Disease
Nirogi, Ramakrishna, Shinde, Anil, Kambhampati, Rama Sastry, Mohammed, Abdul Rasheed, Saraf, Sangram Keshari, Badange, Rajesh kumar, Bandyala, Thrinath Reddy, Bhatta, Venugopalarao, Bojja, Kumar, Reballi, Veena, Subramanian, Ramkumar, Benade, Vijay, Palacharla, Raghava Choudary, Bhyrapuneni, Gopinadh, Jayarajan, Pradeep, Goyal, Vinod, Jasti, Venkat
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
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Journal Article
Discovery and Development of N‑[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Active Histamine H3 Receptor Inverse Agonist with Robust Wake-Promoting Activity
Nirogi, Ramakrishna, Shinde, Anil, Mohammed, Abdul Rasheed, Badange, Rajesh Kumar, Reballi, Veena, Bandyala, Thrinath Reddy, Saraf, Sangram Keshari, Bojja, Kumar, Manchineella, Sravanthi, Achanta, Pramod Kumar, Kandukuri, Kiran Kumar, Subramanian, Ramkumar, Benade, Vijay, Palacharla, Raghava Choudary, Jayarajan, Pradeep, Pandey, Santoshkumar, Jasti, Venkat
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
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