A recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis
Lindzen, M, Carvalho, S, Starr, A, Ben-Chetrit, N, Pradeep, C-R, Köstler, W J, Rabinkov, A, Lavi, S, Bacus, S S, Yarden, Y
Published in Oncogene (26.07.2012)
Published in Oncogene (26.07.2012)
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Synergistic Down-Regulation of Receptor Tyrosine Kinases by Combinations of mAbs: Implications for Cancer Immunotherapy
Friedman, Lilach M., Rinon, Ariel, Schechter, Bilha, Lyass, Ljuba, Lavi, Sara, Bacus, Sarah S., Sela, Michael, Yarden, Yosef
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2005)
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Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53
BACUS, Sarah S, GUDKOV, Andrei V, LOWE, Michael, LYASS, Ljuba, YUNG, Yuval, KOMAROV, Andrei P, KEYOMARSI, Khandan, YARDEN, Yosef, SEGER, Rony
Published in Oncogene (11.01.2001)
Published in Oncogene (11.01.2001)
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Cyclin E and Survival in Patients with Breast Cancer
Keyomarsi, Khandan, Tucker, Susan L, Buchholz, Thomas A, Callister, Matthew, Ding, Ye, Hortobagyi, Gabriel N, Bedrosian, Isabelle, Knickerbocker, Christopher, Toyofuku, Wendy, Lowe, Michael, Herliczek, Thaddeus W, Bacus, Sarah S
Published in The New England journal of medicine (14.11.2002)
Published in The New England journal of medicine (14.11.2002)
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Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells
Spector, Neil L, Yarden, Yosef, Smith, Bradley, Lyass, Ljuba, Trusk, Patricia, Pry, Karen, Hill, Jason E, Xia, Wenle, Seger, Rony, Bacus, Sarah S
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2007)
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The efficacy of Herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins
SMITH, B. L, CHIN, D, MALTZMAN, W, CROSBY, K, HORTOBAGYI, G. N, BACUS, S. S
Published in British journal of cancer (13.09.2004)
Published in British journal of cancer (13.09.2004)
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218 Genomic analysis identifies novel drivers and targetable pathways in inflammatory breast cancer patient samples
Moran, D.M, Rao, K, Bacon-Trusk, P, Pry, K, Weigman, V, Velculescu, V, Cristofanilli, M, Bacus, S
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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Activation of AMPK is necessary for killing cancer cells and sparing cardiac cells
Shell, Scott A, Lyass, Ljuba, Trusk, Patricia B, Pry, Karen J, Wappel, Robert L, Bacus, Sarah S
Published in Cell cycle (Georgetown, Tex.) (15.06.2008)
Published in Cell cycle (Georgetown, Tex.) (15.06.2008)
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Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity
Kochupurakkal, Bose S., Harari, Daniel, Di-Segni, Ayelet, Maik-Rachline, Galia, Lyass, Ljuba, Gur, Gal, Kerber, Gabriele, Citri, Ami, Lavi, Sara, Eilam, Raya, Chalifa-Caspi, Vered, Eshhar, Zelig, Pikarsky, Eli, Pinkas-Kramarski, Ronit, Bacus, Sarah S., Yarden, Yosef
Published in The Journal of biological chemistry (04.03.2005)
Published in The Journal of biological chemistry (04.03.2005)
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Prognostic significance of phosphorylated P38 mitogen‐activated protein kinase and HER‐2 expression in lymph node‐positive breast carcinoma
Esteva, Francisco J., Sahin, Aysegul A., Smith, Terry L., Yang, Ying, Pusztai, Lajos, Nahta, Rita, Buchholz, Thomas A., Buzdar, Aman U., Hortobagyi, Gabriel N., Bacus, Sarah S.
Published in Cancer (01.02.2004)
Published in Cancer (01.02.2004)
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Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
Wen, Duanzhi, Peles, Elior, Cupples, Rod, Suggs, Sidney V., Bacus, Sarah S., Luo, Yi, Trail, Geraldine, Hu, Sylvia, Silbiger, Scott M., Levy, Rachel Ben, Koski, Raymond A., Lu, Hsieng S., Yarden, Yosef
Published in Cell (01.05.1992)
Published in Cell (01.05.1992)
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Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo
Komarova, Elena A., Chernov, Mikhail V., Franks, Roberta, Wang, Kaihua, Armin, Gabriella, Zelnick, Carolyn R., Chin, Dot M., Bacus, Sarah S., Stark, George R., Gudkov, Andrei V.
Published in The EMBO journal (17.03.1997)
Published in The EMBO journal (17.03.1997)
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AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival
BACUS, Sarah S, ALTOMARE, Deborah A, LYASS, Ljuba, DOT MON CHIN, FARRELL, Michael P, GUROVA, Katerina, GUDKOV, Andrei, TESTA, Joseph R
Published in Oncogene (16.05.2002)
Published in Oncogene (16.05.2002)
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Epiregulin Is a Potent Pan-ErbB Ligand That Preferentially Activates Heterodimeric Receptor Complexes
Shelly, Maya, Pinkas-Kramarski, Ronit, Guarino, Bradley C., Waterman, Hadassa, Wang, Ling-Mei, Lyass, Ljuba, Alimandi, Mauricio, Kuo, Angera, Bacus, Sarah S., Pierce, Jacalyn H., Andrews, Glenn C., Yarden, Yosef
Published in The Journal of biological chemistry (24.04.1998)
Published in The Journal of biological chemistry (24.04.1998)
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Isolation of the neu/HER-2 stimulatory ligand : a 44 kd glycoprotein that induces differentiation of mammary tumor cells
PELES, E, BACUS, S. S, KOSKI, R. A, LU, H. S, WEN, D, OGDEN, S. G, LEVY, R. B, YARDE, Y
Published in Cell (03.04.1992)
Published in Cell (03.04.1992)
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The oncogenic ErbB-2/ErbB-3 heterodimer is a surrogate receptor of the epidermal growth factor and betacellulin
PINKAS-KRAMARSKI, R, LENFERINK, A. E. G, BACUS, S. S, LYASS, L, VAN DE POLL, M. L. M, KLAPPER, L. N, TZAHAR, E, SELA, M, VAN ZOELEN, E. J. J, YARDEN, Y
Published in Oncogene (12.03.1998)
Published in Oncogene (12.03.1998)
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KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells
Moran, Diarmuid M, Trusk, Patricia B, Pry, Karen, Paz, Keren, Sidransky, David, Bacus, Sarah S
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
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An Immunological Approach Reveals Biological Differences between the Two NDF/Heregulin Receptors, ErbB-3 and ErbB-4 (∗)
Chen, Xiaomei, Levkowitz, Gil, Tzahar, Eldad, Karunagaran, Devarajan, Lavi, Sara, Ben-Baruch, Noa, Leitner, Orith, Ratzkin, Barry J., Bacus, Sarah S., Yarden, Yosef
Published in The Journal of biological chemistry (29.03.1996)
Published in The Journal of biological chemistry (29.03.1996)
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