Electrophilic trifluoromethanesulfanylation of indole derivatives
Ferry, Aurélien, Billard, Thierry, Bacqué, Eric, Langlois, Bernard R.
Published in Journal of fluorine chemistry (01.02.2012)
Published in Journal of fluorine chemistry (01.02.2012)
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Trifluoromethanesulfanylamides as Easy-to-Handle Equivalents of the Trifluoromethanesulfanyl Cation (CF₃S⁺): Reaction with Alkenes and Alkynes
Ferry, Aurélien, Billard, Thierry, Langlois, Bernard R, Bacqué, Eric
Published in Angewandte Chemie (International ed.) (26.10.2009)
Published in Angewandte Chemie (International ed.) (26.10.2009)
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A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance
Germe, Thomas, Vörös, Judit, Jeannot, Frederic, Taillier, Thomas, Stavenger, Robert A, Bacqué, Eric, Maxwell, Anthony, Bax, Benjamin D
Published in Nucleic acids research (04.05.2018)
Published in Nucleic acids research (04.05.2018)
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Journal Article
Synthesis of Trifluoromethanesulfinamidines and -sulfanylamides
Ferry, Aurélien, Billard, Thierry, Langlois, Bernard R, Bacqué, Eric
Published in Journal of organic chemistry (05.12.2008)
Published in Journal of organic chemistry (05.12.2008)
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Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition
Ballinger, Elaine, Mosior, John, Hartman, Travis, Burns-Huang, Kristin, Gold, Ben, Morris, Roxanne, Goullieux, Laurent, Blanc, Isabelle, Vaubourgeix, Julien, Lagrange, Sophie, Fraisse, Laurent, Sans, Stéphanie, Couturier, Cedric, Bacqué, Eric, Rhee, Kyu, Scarry, Sarah M, Aubé, Jeffrey, Yang, Guangbin, Ouerfelli, Ouathek, Schnappinger, Dirk, Ioerger, Thomas R, Engelhart, Curtis A, McConnell, Jennifer A, McAulay, Kathrine, Fay, Allison, Roubert, Christine, Sacchettini, James, Nathan, Carl
Published in Science (American Association for the Advancement of Science) (01.02.2019)
Published in Science (American Association for the Advancement of Science) (01.02.2019)
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Optimization of the Antibacterial Spectrum and the Developability Profile of the Novel-Class Natural Product Corramycin
Renard, Stephane, Versluys, Stéphanie, Taillier, Thomas, Dubarry, Nelly, Leroi-Geissler, Corinne, Rey, Astrid, Cornaire, Emilie, Sordello, Sylvie, Carry, Jean-Christophe B., Angouillant-Boniface, Odile, Gouyon, Thierry, Thompson, Fabienne, Lebourg, Gilles, Certal, Victor, Balazs, Laszlo, Arranz, Esther, Doerflinger, Gilles, Bretin, Francois, Gervat, Vincent, Brohan, Eric, Kraft, Volker, Boulenc, Xavier, Ducelier, Cécile, Bacqué, Eric, Couturier, Cédric
Published in Journal of medicinal chemistry (28.12.2023)
Published in Journal of medicinal chemistry (28.12.2023)
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Journal Article
Fluoroquinolone structure and translocation flux across bacterial membrane
Vergalli, Julia, Dumont, Estelle, Cinquin, Bertrand, Maigre, Laure, Pajovic, Jelena, Bacqué, Eric, Mourez, Michael, Réfrégiers, Matthieu, Pagès, Jean-Marie
Published in Scientific reports (29.08.2017)
Published in Scientific reports (29.08.2017)
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In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas
Ottavi, Samantha, Scarry, Sarah M, Mosior, John, Ling, Yan, Roberts, Julia, Singh, Amrita, Zhang, David, Goullieux, Laurent, Roubert, Christine, Bacqué, Eric, Lagiakos, H. Rachel, Vendome, Jeremie, Moraca, Francesca, Li, Kelin, Perkowski, Andrew J, Ramesh, Remya, Bowler, Matthew M, Tracy, William, Feher, Victoria A, Sacchettini, James C, Gold, Ben S, Nathan, Carl F, Aubé, Jeffrey
Published in Journal of medicinal chemistry (10.02.2022)
Published in Journal of medicinal chemistry (10.02.2022)
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Journal Article
Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1‑{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3‑b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844)
Ugolini, Antonio, Kenigsberg, Mireille, Rak, Alexey, Vallée, Francois, Houtmann, Jacques, Lowinski, Maryse, Capdevila, Cécile, Khider, Jean, Albert, Eva, Martinet, Nathalie, Nemecek, Conception, Grapinet, Sandrine, Bacqué, Eric, Roesner, Manfred, Delaisi, Christine, Calvet, Loreley, Bonche, Fabrice, Semiond, Dorothée, Egile, Coumaran, Goulaouic, Hélène, Schio, Laurent
Published in Journal of medicinal chemistry (11.08.2016)
Published in Journal of medicinal chemistry (11.08.2016)
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Optimization of the Central α-Amino Acid in Cystobactamids to the Broad-Spectrum, Resistance-Breaking Antibiotic CN-CC-861
Kohnhäuser, Daniel, Seedorf, Tim, Cirnski, Katarina, Heimann, Dominik, Coetzee, Janetta, Sordello, Sylvie, Richter, Jana, Stappert, Moritz, Sabuco, Jean-Francois, Corbett, David, Bacqué, Eric, Rox, Katharina, Herrmann, Jennifer, Vassort, Aurelie, Müller, Rolf, Kirschning, Andreas, Brönstrup, Mark
Published in Journal of medicinal chemistry (20.09.2024)
Published in Journal of medicinal chemistry (20.09.2024)
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Journal Article
Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase
Chan, Pan F., Germe, Thomas, Bax, Benjamin D., Huang, Jianzhong, Thalji, Reema K., Bacqué, Eric, Checchia, Anna, Chen, Dongzhao, Cui, Haifeng, Ding, Xiao, Ingraham, Karen, McCloskey, Lynn, Raha, Kaushik, Srikannathasan, Velupillai, Maxwell, Anthony, Stavenger, Robert A.
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2017)
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Journal Article
Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas
Ottavi, Samantha, Li, Kelin, Cacioppo, Jackson G., Perkowski, Andrew J., Ramesh, Remya, Gold, Ben S., Ling, Yan, Roberts, Julia, Singh, Amrita, Zhang, David, Mosior, John, Goullieux, Laurent, Roubert, Christine, Bacqué, Eric, Sacchettini, James C., Nathan, Carl F., Aubé, Jeffrey
Published in ACS medicinal chemistry letters (13.07.2023)
Published in ACS medicinal chemistry letters (13.07.2023)
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Journal Article
Imidazopyrazinones (IPYs): Non-Quinolone Bacterial Topoisomerase Inhibitors Showing Partial Cross-Resistance with Quinolones
Jeannot, Frédéric, Taillier, Thomas, Despeyroux, Pierre, Renard, Stéphane, Rey, Astrid, Mourez, Michaël, Poeverlein, Christoph, Khichane, Imène, Perrin, Marc-Antoine, Versluys, Stéphanie, Stavenger, Robert A, Huang, Jianzhong, Germe, Thomas, Maxwell, Anthony, Cao, Sha, Huseby, Douglas L, Hughes, Diarmaid, Bacqué, Eric
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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Journal Article
Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin
Couturier, Cédric, Groß, Sebastian, Tesmar, Alexander, Hoffmann, Judith, Deckarm, Selina, Fievet, Anouchka, Dubarry, Nelly, Taillier, Thomas, Pöverlein, Christoph, Stump, Heike, Kurz, Michael, Toti, Luigi, Haag Richter, Sabine, Schummer, Dietmar, Sizun, Philippe, Hoffmann, Michael, Prasad Awal, Ram, Zaburannyi, Nestor, Harmrolfs, Kirsten, Wink, Joachim, Lessoud, Emilie, Vermat, Thierry, Cazals, Veronique, Silve, Sandra, Bauer, Armin, Mourez, Michael, Fraisse, Laurent, Leroi‐Geissler, Corinne, Rey, Astrid, Versluys, Stéphanie, Bacqué, Eric, Müller, Rolf, Renard, Stephane
Published in Angewandte Chemie International Edition (19.12.2022)
Published in Angewandte Chemie International Edition (19.12.2022)
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Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)
Couturier, Cédric, Ronzon, Quentin, Lattanzi, Giulia, Lingard, Iain, Coyne, Sebastien, Cazals, Veronique, Dubarry, Nelly, Yvon, Stephane, Leroi-Geissler, Corinne, Gracia, Obdulia Rabal, Teague, Joanne, Sordello, Sylvie, Corbett, David, Bauch, Caroline, Monlong, Chantal, Payne, Lloyd, Taillier, Thomas, Fuchs, Hazel, Broenstrup, Mark, Harrison, Peter H., Moynié, Lucile, Lakshminarayanan, Abirami, Gianga, Tiberiu-Marius, Hussain, Rohanah, Naismith, James H., Mourez, Michael, Bacqué, Eric, Björkling, Fredrik, Sabuco, Jean-Francois, Franzyk, Henrik
Published in European journal of medicinal chemistry (05.02.2024)
Published in European journal of medicinal chemistry (05.02.2024)
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Journal Article
Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A
Jürjens, Gerrit, Schuler, Sören M. M., Kurz, Michael, Petit, Sylvain, Couturier, Cédric, Jeannot, Frédéric, Nguyen, Fabian, Wende, Raffael C., Hammann, Peter E., Wilson, Daniel N., Bacqué, Eric, Pöverlein, Christoph, Bauer, Armin
Published in Angewandte Chemie International Edition (10.09.2018)
Published in Angewandte Chemie International Edition (10.09.2018)
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Journal Article
Identification and optimization of a new series of anti-tubercular quinazolinones
Couturier, Cédric, Lair, Christine, Pellet, Alain, Upton, Anna, Kaneko, Takushi, Perron, Corinne, Cogo, Eric, Menegotto, Jérome, Bauer, Armin, Scheiper, Bodo, Lagrange, Sophie, Bacqué, Eric
Published in Bioorganic & medicinal chemistry letters (01.11.2016)
Published in Bioorganic & medicinal chemistry letters (01.11.2016)
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Journal Article
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA
Lopez Quezada, Landys, Silve, Sandra, Kelinske, Mark, Liba, Amir, Diaz Gonzalez, Constantino, Kotev, Martin, Goullieux, Laurent, Sans, Stephanie, Roubert, Christine, Lagrange, Sophie, Bacqué, Eric, Couturier, Cedric, Pellet, Alain, Blanc, Isabelle, Ferron, Marlène, Debu, Fabrice, Li, Kelin, Aubé, Jeffrey, Roberts, Julia, Little, David, Ling, Yan, Zhang, Jun, Gold, Ben, Nathan, Carl
Published in mBio (09.07.2019)
Published in mBio (09.07.2019)
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Approach Toward the Total Synthesis of Griseoviridin: Formation of Thioethynyl and Thiovinyl Ether-Containing Nine-Membered Lactones through a Thioalkynylation−Macrolactonization−Hydrostannylation Sequence
Kuligowski, Carine, Bezzenine-Lafollée, Sophie, Chaume, Grégory, Mahuteau, Jacqueline, Barrière, Jean-Claude, Bacqué, Eric, Pancrazi, Ange, Ardisson, Janick
Published in Journal of organic chemistry (28.06.2002)
Published in Journal of organic chemistry (28.06.2002)
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