MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction
Boehme, Stefen A, Franz-Bacon, Karin, Ludka, John, DiTirro, Danielle N, Ly, Tai Wei, Bacon, Kevin B
Published in PloS one (09.12.2016)
Published in PloS one (09.12.2016)
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Targeting MAP3K19 prevents human lung myofibroblast activation both in vitro and in a humanized SCID model of idiopathic pulmonary fibrosis
Jones, Isabelle C., Espindola, Milena S., Narayanan, Rohan, Coelho, Ana L., Habiel, David M., Boehme, Stefen A., Ly, Tai Wei, Bacon, Kevin B., Hogaboam, Cory M.
Published in Scientific reports (24.12.2019)
Published in Scientific reports (24.12.2019)
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Case report: Long-term follow-up of patients who received a FimCH vaccine for prevention of recurrent urinary tract infections caused by antibiotic resistant Enterobacteriaceae: a case report series
Perer, Elise, Stacey, Helen, Eichorn, Terri, Hughey, Heidi, Lawrence, Julie, Cunningham, Eric, Johnson, Mark O'Neil, Bacon, Kevin, Kau, Andrew, Hultgren, Scott J, Hooton, Thomas M, Harris, Jennifer L
Published in Frontiers in immunology (13.03.2024)
Published in Frontiers in immunology (13.03.2024)
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Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4
Golfier, Sven, Kondo, Shinichi, Schulze, Tobias, Takeuchi, Tomomi, Vassileva, Galya, Achtman, Ariel H, Gräler, Markus H, Abbondanzo, Susan J, Wiekowski, Maria, Kremmer, Elisabeth, Endo, Yasuhisa, Lira, Sergio A, Bacon, Kevin B, Lipp, Martin
Published in The FASEB journal (01.12.2010)
Published in The FASEB journal (01.12.2010)
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CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells
Liu, Ningshu, Ohnishi, Noriko, Ni, Lin, Akira, Shizuo, Bacon, Kevin B
Published in Nature immunology (01.07.2003)
Published in Nature immunology (01.07.2003)
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Lysophosphatidic acid receptor 1 antagonist (EPGN2154) causes regression of NASH in preclinical NASH models
Bhattacharjee, Jashdeep, Beaton, Graham, Ravula, Satheesh B, Lee, Suk Joong, Bacon, Kevin B, Jenkinson, Celia P, Warren, Mikako, Tucci, Fabio C, Kohli, Rohit
Published in Hepatology communications (01.12.2023)
Published in Hepatology communications (01.12.2023)
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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation
Boehme, Stefen A., Franz-Bacon, Karin, Chen, Edward P., Šášik, Roman, Sprague, L. James, Ly, Tai Wei, Hardiman, Gary, Bacon, Kevin B.
Published in International immunology (01.01.2009)
Published in International immunology (01.01.2009)
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Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P
Golfier, Sven, Kondo, Shinichi, Schulze, Tobias, Takeuchi, Tomomi, Vassileva, Galya, Achtman, Ariel H, Gräler, Markus H, Abbondanzo, Susan J, Wiekowski, Maria, Kremmer, Elisabeth, Endo, Yasuhisa, Lira, Sergio A, Bacon, Kevin B, Lipp, Martin
Published in The FASEB journal (01.12.2010)
Published in The FASEB journal (01.12.2010)
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An Orally Bioavailable Small Molecule Antagonist of CRTH2, Ramatroban (BAY u3405), Inhibits Prostaglandin D2-Induced Eosinophil Migration in Vitro
Sugimoto, Hiromi, Shichijo, Michitaka, Iino, Takashi, Manabe, Yoshihisa, Watanabe, Akihiko, Shimazaki, Makoto, Gantner, Florian, Bacon, Kevin B
Published in The Journal of pharmacology and experimental therapeutics (01.04.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2003)
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The Orally Available Spleen Tyrosine Kinase Inhibitor 2-[7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide Dihydrochloride (BAY 61-3606) Blocks Antigen-Induced Airway Inflammation in Rodents
Yamamoto, Noriyuki, Takeshita, Keisuke, Shichijo, Michitaka, Kokubo, Toshio, Sato, Masako, Nakashima, Kosuke, Ishimori, Mina, Nagai, Hiroichi, Li, Ying-Fu, Yura, Takeshi, Bacon, Kevin B
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
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CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation
Lukacs, Nicholas W, Berlin, Aaron A, Franz-Bacon, Karin, Sasik, Roman, Sprague, L. James, Ly, Tai Wei, Hardiman, Gary, Boehme, Stefen A, Bacon, Kevin B
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2008)
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2008)
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A selective novel low‐molecular‐weight inhibitor of IκB kinase‐β (IKK‐β) prevents pulmonary inflammation and shows broad anti‐inflammatory activity
Ziegelbauer, Karl, Gantner, Florian, Lukacs, Nicholas W, Berlin, Aaron, Fuchikami, Kinji, Niki, Toshiro, Sakai, Katsuya, Inbe, Hisayo, Takeshita, Keisuke, Ishimori, Mina, Komura, Hiroshi, Murata, Toshiki, Lowinger, Timothy, Bacon, Kevin B
Published in British journal of pharmacology (01.05.2005)
Published in British journal of pharmacology (01.05.2005)
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The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors
Wu, Jane Y, Feng, Lili, Park, Hwan-Tae, Havlioglu, Necat, Wen, Leng, Tang, Hao, Bacon, Kevin B, Jiang, Zhi-hong, Zhang, Xiao-chun, Rao, Yi
Published in Nature (London) (19.04.2001)
Published in Nature (London) (19.04.2001)
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Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2)
Boehme, Stefen A., Franz-Bacon, Karin, Chen, Edward P., Ly, Tai Wei, Kawakami, Yuko, Bacon, Kevin B.
Published in International immunology (01.06.2009)
Published in International immunology (01.06.2009)
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A new class of membrane-bound chemokine with a CX3C motif
BAZAN, J. F, BACON, K. B, HARDIMAN, G, WANG, W, SOO, K, ROSSI, D, GREAVES, D. R, ZLOTNIK, A, SCHALL, T. J
Published in Nature (London) (13.02.1997)
Published in Nature (London) (13.02.1997)
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Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms
Boehme, Stefen A., Chen, Edward P., Franz-Bacon, Karin, Šášik, Roman, Sprague, L. James, Ly, Tai Wei, Hardiman, Gary, Bacon, Kevin B.
Published in International immunology (01.01.2009)
Published in International immunology (01.01.2009)
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Cinnabaramides A−G: Analogues of Lactacystin and Salinosporamide from a Terrestrial Streptomycete
Stadler, Marc, Bitzer, Jens, Mayer-Bartschmid, Anke, Müller, Hartwig, Benet-Buchholz, Jordi, Gantner, Florian, Tichy, Hans-Volker, Reinemer, Peter, Bacon, Kevin B
Published in Journal of natural products (Washington, D.C.) (01.02.2007)
Published in Journal of natural products (Washington, D.C.) (01.02.2007)
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Growth Inhibition of Multiple Myeloma Cells by a Novel IκB Kinase Inhibitor
SANDA, Takaomi, IIDA, Shinsuke, OGURA, Hiroka, ASAMITSU, Kaori, MURATA, Toshiki, BACON, Kevin B, UEDA, Ryuzo, OKAMOTO, Takashi
Published in Clinical cancer research (01.03.2005)
Published in Clinical cancer research (01.03.2005)
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