Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development
Liu, Shihui, Bachran, Christopher, Gupta, Pradeep, Miller-Randolph, Sharmina, Wang, Hailun, Crown, Devorah, Zhang, Yi, Wein, Alexander N, Singh, Rajat, Fattah, Rasem, Leppla, Stephen H
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
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Journal Article
Saponins in tumor therapy
Bachran, Christopher, Bachran, Silke, Sutherland, Mark, Bachran, Diana, Fuchs, Hendrik
Published in Mini reviews in medicinal chemistry (01.06.2008)
Published in Mini reviews in medicinal chemistry (01.06.2008)
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Journal Article
A convenient method for saponin isolation in tumour therapy
Weng, Alexander, Jenett-Siems, Kristina, Schmieder, Peter, Bachran, Diana, Bachran, Christopher, Görick, Cornelia, Thakur, Mayank, Fuchs, Hendrik, Melzig, Matthias F.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2010)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2010)
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Journal Article
Inhibition of tumor growth by targeted toxins in mice is dramatically improved by saponinum album in a synergistic way
Bachran, Christopher, Dürkop, Horst, Sutherland, Mark, Bachran, Diana, Müller, Christian, Weng, Alexander, Melzig, Matthias F, Fuchs, Hendrik
Published in Journal of immunotherapy (1997) (01.09.2009)
Published in Journal of immunotherapy (1997) (01.09.2009)
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Journal Article
Combined application of saponin and chimeric toxins drastically enhances the targeted cytotoxicity on tumor cells
Heisler, Iring, Sutherland, Mark, Bachran, Christopher, Hebestreit, Philipp, Schnitger, Anna, Melzig, Matthias F., Fuchs, Hendrik
Published in Journal of controlled release (18.08.2005)
Published in Journal of controlled release (18.08.2005)
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Journal Article
Creation and characterization of a xenograft model for human cervical cancer
Hoffmann, Corinna, Bachran, Christopher, Stanke, Jonas, Elezkurtaj, Sefer, Kaufmann, Andreas M, Fuchs, Hendrick, Loddenkemper, Christoph, Schneider, Achim, Cichon, Günter
Published in Gynecologic oncology (01.07.2010)
Published in Gynecologic oncology (01.07.2010)
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Journal Article
The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure
Bachran, Christopher, Sutherland, Mark, Heisler, Iring, Hebestreit, Philipp, Melzig, Matthias F, Fuchs, Hendrik
Published in Experimental biology and medicine (Maywood, N.J.) (01.04.2006)
Published in Experimental biology and medicine (Maywood, N.J.) (01.04.2006)
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Journal Article
Chimeric toxins inhibit growth of primary oral squamous cell carcinoma cells
Bachran, Christopher, Heisler, Iring, Bachran, Diana, Dassler, Katrin, Melzig, Matthias F., Ervens, Jürgen, Fuchs, Hendrik
Published in Cancer biology & therapy (01.02.2008)
Published in Cancer biology & therapy (01.02.2008)
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Journal Article
Sortase-A mediated chemoenzymatic lipidation of single-domain antibodies for cell membrane engineering
Wöll, Steffen, Bachran, Christopher, Schiller, Stefan, Swee, Lee Kim, Scherließ, Regina
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2020)
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2020)
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Journal Article
Highly sensitive, selective and label-free protein detection in physiological solutions using carbon nanotube transistors with nanobody receptors
Filipiak, Marcin S., Rother, Marcel, Andoy, Nesha M., Knudsen, Arne C., Grimm, Stefan, Bachran, Christopher, Swee, Lee Kim, Zaumseil, Jana, Tarasov, Alexey
Published in Sensors and actuators. B, Chemical (01.02.2018)
Published in Sensors and actuators. B, Chemical (01.02.2018)
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Journal Article
Pentaglycine lipid derivates – rp-HPLC analytics for bioorthogonal anchor molecules in targeted, multiple-composite liposomal drug delivery systems
Wöll, Steffen, Schiller, Stefan, Bachran, Christopher, Swee, Lee Kim, Scherließ, Regina
Published in International journal of pharmaceutics (25.08.2018)
Published in International journal of pharmaceutics (25.08.2018)
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Journal Article
Sortaggable liposomes: Evaluation of reaction conditions for single-domain antibody conjugation by Sortase-A and targeting of CD11b+ myeloid cells
Wöll, Steffen, Bachran, Christopher, Schiller, Stefan, Schröder, Matthias, Conrad, Lena, Swee, Lee Kim, Scherließ, Regina
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2018)
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2018)
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Journal Article
Sortagging of liposomes with a murine CD11b-specific VHH increases in vitro and in vivo targeting specificity of myeloid cells
Wöll, Steffen, Bachran, Christopher, Schiller, Stefan, Schröder, Matthias, Conrad, Lena, Scherließ, Regina, Swee, Lee Kim
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2019)
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2019)
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Journal Article
Genetic screen in myeloid cells identifies TNF-α autocrine secretion as a factor increasing MDSC suppressive activity via Nos2 up-regulation
Schröder, Matthias, Krötschel, Marit, Conrad, Lena, Naumann, Svenja Kerstin, Bachran, Christopher, Rolfe, Alex, Umansky, Viktor, Helming, Laura, Swee, Lee Kim
Published in Scientific reports (07.09.2018)
Published in Scientific reports (07.09.2018)
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Journal Article
Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical Screening
Schröder, Matthias, Loos, Simone, Naumann, Svenja Kerstin, Bachran, Christopher, Krötschel, Marit, Umansky, Viktor, Helming, Laura, Swee, Lee Kim
Published in The Journal of immunology (1950) (01.05.2017)
Published in The Journal of immunology (1950) (01.05.2017)
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Journal Article
The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent
Bachran, Christopher, Schröder, Matthias, Conrad, Lena, Cragnolini, Juan J., Tafesse, Fikadu G., Helming, Laura, Ploegh, Hidde L., Swee, Lee Kim
Published in Scientific reports (20.12.2017)
Published in Scientific reports (20.12.2017)
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Journal Article