Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
Pascal, Kristen E, Christopher M. Coleman, Alejandro O. Mujica, Vishal Kamat, Ashok Badithe, Jeanette Fairhurst, Charleen Hunt, John Strein, Alexander Berrebi, Jeanne M. Sisk, Krystal L. Matthews, Robert Babb, Gang Chen, Ka-Man V. Lai, Tammy T. Huang, William Olson, George D. Yancopoulos, Neil Stahl, Matthew B. Frieman, Christos A. Kyratsous
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Get full text
Journal Article
Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5
Latuszek, Adrianna, Liu, Yashu, Olsen, Olav, Foster, Randi, Cao, Marc, Lovric, Irena, Yuan, Ming, Liu, Nina, Chen, Henry, Zhang, Qian, Xiao, Hui, Springer, Carola, Ehrlich, George, Kamat, Vishal, Rafique, Ashique, Hu, Ying, Krueger, Pamela, Huang, Tammy, Poueymirou, William, Babb, Robert, Rosconi, Michael P, Retter, Marc W, Chen, Gang, Morton, Lori, Zambrowicz, Brian, Cao, Jingtai, Romano, Carmelo, Olson, William C
Published in PloS one (08.05.2020)
Published in PloS one (08.05.2020)
Get full text
Journal Article
A novel bispecific antibody platform to direct complement activity for efficient lysis of target cells
Cruz, Jonathan W, Damko, Ermelinda, Modi, Bhavika, Tu, Naxin, Meagher, Karoline, Voronina, Vera, Gartner, Hans, Ehrlich, George, Rafique, Ashique, Babb, Robert, Aneja, Priya, Potocky, Terra B, D' Orvilliers, Amanda, Coppi, Alida, E, Sook Yen, Qiu, Haibo, Williams, Courtney M, Bennett, Brandy L, Chen, Gang, Macdonald, Lynn, Olson, William, Lin, John C, Stahl, Neil, Murphy, Andrew J, Kyratsous, Christos A, Prasad, Brinda C
Published in Scientific reports (19.08.2019)
Published in Scientific reports (19.08.2019)
Get full text
Journal Article
Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain
Somersan-Karakaya, Selin, Turner, Kenneth C., Cortes-Burgos, Luz, Miller, Jutta, LaCroix-Fralish, Michael, Logovinsky, Veronika, Patel, Yamini, Torres, Richard, Ganguly, Samit, Breazna, Aurora, DeVeaux, Michelle, Bhore, Rafia, Gao, Min, Delfino, Frank J., Rafique, Ashique, Fairhurst, Jeanette L., Hunt, Charleen, Babb, Robert, Badithe, Ashok, Poueymirou, William T., Surowitz, Ronald, Rottey, Sylvie, Murphy, Andrew J., Harari, Olivier, Macdonald, Lynn E., Croll, Susan D.
Published in Neurobiology of pain (01.08.2023)
Published in Neurobiology of pain (01.08.2023)
Get full text
Journal Article
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
Hansen, Johanna, Baum, Alina, Pascal, Kristen E, Russo, Vincenzo, Giordano, Stephanie, Wloga, Elzbieta, Fulton, Benjamin O, Yan, Ying, Koon, Katrina, Patel, Krunal, Chung, Kyung Min, Hermann, Aynur, Ullman, Erica, Cruz, Jonathan, Rafique, Ashique, Huang, Tammy, Fairhurst, Jeanette, Libertiny, Christen, Malbec, Marine, Lee, Wen-Yi, Welsh, Richard, Farr, Glen, Pennington, Seth, Deshpande, Dipali, Cheng, Jemmie, Watty, Anke, Bouffard, Pascal, Babb, Robert, Levenkova, Natasha, Chen, Calvin, Zhang, Bojie, Romero Hernandez, Annabel, Saotome, Kei, Zhou, Yi, Franklin, Matthew, Sivapalasingam, Sumathi, Lye, David Chien, Weston, Stuart, Logue, James, Haupt, Robert, Frieman, Matthew, Chen, Gang, Olson, William, Murphy, Andrew J, Stahl, Neil, Yancopoulos, George D, Kyratsous, Christos A
Published in Science (21.08.2020)
Published in Science (21.08.2020)
Get full text
Journal Article
Web Resource
An mRNA Splice Variant of the AFX Gene with Altered Transcriptional Activity
Yang, Zhenyu, Whelan, James, Babb, Robert, Bowen, Benjamin R.
Published in The Journal of biological chemistry (08.03.2002)
Published in The Journal of biological chemistry (08.03.2002)
Get full text
Journal Article
DNA Recognition by the Herpes Simplex Virus Transactivator VP16: a Novel DNA-Binding Structure
Babb, Robert, Huang, C. Chris, Aufiero, Deborah J., Herr, Winship
Published in Molecular and Cellular Biology (01.07.2001)
Published in Molecular and Cellular Biology (01.07.2001)
Get full text
Journal Article
Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates
Pascal, Kristen E, Dudgeon, Drew, Trefry, John C, Anantpadma, Manu, Sakurai, Yasuteru, Murin, Charles D, Turner, Hannah L, Fairhurst, Jeanette, Torres, Marcela, Rafique, Ashique, Yan, Ying, Badithe, Ashok, Yu, Kevin, Potocky, Terra, Bixler, Sandra L, Chance, Taylor B, Pratt, William D, Rossi, Franco D, Shamblin, Joshua D, Wollen, Suzanne E, Zelko, Justine M, Carrion, Jr, Ricardo, Worwa, Gabriella, Staples, Hilary M, Burakov, Darya, Babb, Robert, Chen, Gang, Martin, Joel, Huang, Tammy T, Erlandson, Karl, Willis, Melissa S, Armstrong, Kimberly, Dreier, Thomas M, Ward, Andrew B, Davey, Robert A, Pitt, Margaret L M, Lipsich, Leah, Mason, Peter, Olson, William, Stahl, Neil, Kyratsous, Christos A
Published in The Journal of Infectious Diseases (22.11.2018)
Published in The Journal of Infectious Diseases (22.11.2018)
Get full text
Journal Article
Web Resource
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning
Haber, Lauric, Olson, Kara, Kelly, Marcus P., Crawford, Alison, DiLillo, David J., Tavaré, Richard, Ullman, Erica, Mao, Shu, Canova, Lauren, Sineshchekova, Olga, Finney, Jennifer, Pawashe, Arpita, Patel, Supriya, McKay, Ryan, Rizvi, Sahar, Damko, Ermelinda, Chiu, Danica, Vazzana, Kristin, Ram, Priyanka, Mohrs, Katja, D’Orvilliers, Amanda, Xiao, Jenny, Makonnen, Sosina, Hickey, Carlos, Arnold, Cody, Giurleo, Jason, Chen, Ya Ping, Thwaites, Courtney, Dudgeon, Drew, Bray, Kevin, Rafique, Ashique, Huang, Tammy, Delfino, Frank, Hermann, Aynur, Kirshner, Jessica R., Retter, Marc W., Babb, Robert, MacDonald, Douglas, Chen, Gang, Olson, William C., Thurston, Gavin, Davis, Samuel, Lin, John C., Smith, Eric
Published in Scientific reports (13.07.2021)
Published in Scientific reports (13.07.2021)
Get full text
Journal Article
A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models
DaSilva, John O, Yang, Katie, Perez Bay, Andres E, Andreev, Julian, Ngoi, Peter, Pyles, Erica, Franklin, Matthew C, Dudgeon, Drew, Rafique, Ashique, Dore, Anthony, Delfino, Frank J, Potocky, Terra B, Babb, Robert, Chen, Gang, MacDonald, Douglas, Olson, William C, Thurston, Gavin, Daly, Christopher
Published in Clinical cancer research (15.03.2020)
Published in Clinical cancer research (15.03.2020)
Get full text
Journal Article
Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy
Waite, Janelle C, Wang, Bei, Haber, Lauric, Hermann, Aynur, Ullman, Erica, Ye, Xuan, Dudgeon, Drew, Slim, Rabih, Ajithdoss, Dharani K, Godin, Stephen J, Ramos, Ilyssa, Wu, Qi, Oswald, Erin, Poon, Patrick, Golubov, Jacquelynn, Grote, Devon, Stella, Jennifer, Pawashe, Arpita, Finney, Jennifer, Herlihy, Evan, Ahmed, Hassan, Kamat, Vishal, Dorvilliers, Amanda, Navarro, Elizabeth, Xiao, Jenny, Kim, Julie, Yang, Shao Ning, Warsaw, Jacqueline, Lett, Clarissa, Canova, Lauren, Schulenburg, Teresa, Foster, Randi, Krueger, Pamela, Garnova, Elena, Rafique, Ashique, Babb, Robert, Chen, Gang, Stokes Oristian, Nicole, Siao, Chia-Jen, Daly, Christopher, Gurer, Cagan, Martin, Joel, Macdonald, Lynn, MacDonald, Douglas, Poueymirou, William, Smith, Eric, Lowy, Israel, Thurston, Gavin, Olson, William, Lin, John C, Sleeman, Matthew A, Yancopoulos, George D, Murphy, Andrew J, Skokos, Dimitris
Published in Science translational medicine (24.06.2020)
Published in Science translational medicine (24.06.2020)
Get more information
Journal Article
MHC-펩타이드 타겟에 결합하는 항원 인식 분자에 대한 오프 타겟 예측 방법
LEE WEN YI, CHEN GANG, SALZLER ROBERT, DHANIK ANKUR, BABB ROBERT, KUNDU KUNAL, SUH DAVID
Year of Publication 09.08.2024
Get full text
Year of Publication 09.08.2024
Patent
Abstract 4555: Selection of CD3 affinity allows generation of T-cell redirecting bispecific antibodies with unique pharmacokinetic and biodistribution properties
Haber, Lauric, Olson, Kara, Babb, Robert, Kelly, Marcus, Crawford, Alison, Retter, Marc, DiLillo, David, Ullman, Erica, Finney, Jennifer, Canova, Lauren, Pawashe, Arpita, Chiu, Danica, Vazzana, Kristin, Ram, Priyanka, Mohrs, Katja, Dorvilliers, Amanda, Xiao, Jenny, Makonnen, Sosina, Hickey, Carlos, Arnold, Cody, Giurleo, Jason, Patel, Supriya, Tavare, Richard, Chen, Ya Ping, Chen, Gang, Olson, William, Thurston, Gavin, Lin, John Chia-Yang, Hermann, Aynur, Kirshner, Jessica, Smith, Eric J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
카파 유전자좌에서 발현된 제한적 람다 경쇄 레퍼토리를 갖는 비-인간 동물 및 이의 용도
MCWHIRTER JOHN, GUO CHUNGUANG, MURPHY ANDREW J, BABB ROBERT, MACDONALD LYNN, HANSEN JOHANNA
Year of Publication 10.02.2022
Get full text
Year of Publication 10.02.2022
Patent
Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties
Macdonald, Lynn E., Meagher, Karoline A., Franklin, Matthew C., Levenkova, Natasha, Hansen, Johanna, Badithe, Ashok T., Zhong, Maggie, Krueger, Pamela, Rafique, Ashique, Tu, Naxin, Shevchuk, James, Wadhwa, Saurabh, Ehrlich, George, Bautista, Joannie, Grant, Craig, Esau, Lakeisha, Poueymirou, William T., Auerbach, Wojtek, Morton, Lori, Babb, Robert, Chen, Gang, Huang, Tammy, MacDonald, Douglas, Graham, Kenneth, Gurer, Cagan, Voronina, Vera A., McWhirter, John R., Guo, Chunguang, Yancopoulos, George D., Murphy, Andrew J.
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Get full text
Journal Article
항-GITR 항체 및 이의 용도
DUDGEON DREW, HUANG YU, SKOKOS DIMITRIS, WANG BEI, BABB ROBERT, SLEEMAN MATTHEW, OLSON WILLIAM, MOLDEN ROSALYNN
Year of Publication 14.11.2022
Get full text
Year of Publication 14.11.2022
Patent