Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection
Flommersfeld, Sophie, Böttcher, Jan P., Ersching, Jonatan, Flossdorf, Michael, Meiser, Philippa, Pachmayr, Ludwig O., Leube, Justin, Hensel, Inge, Jarosch, Sebastian, Zhang, Qin, Chaudhry, M. Zeeshan, Andrae, Immanuel, Schiemann, Matthias, Busch, Dirk.H., Cicin-Sain, Luka, Sun, Joseph C., Gasteiger, Georg, Victora, Gabriel D., Höfer, Thomas, Buchholz, Veit R., Grassmann, Simon
Published in Immunity (Cambridge, Mass.) (12.10.2021)
Published in Immunity (Cambridge, Mass.) (12.10.2021)
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Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens
Schulz, Oliver, Hanč, Pavel, Böttcher, Jan P., Hoogeboom, Robbert, Diebold, Sandra S., Tolar, Pavel, Reis e Sousa, Caetano
Published in Cell reports (Cambridge) (10.07.2018)
Published in Cell reports (Cambridge) (10.07.2018)
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IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function
Böttcher, Jan P., Schanz, Oliver, Garbers, Christoph, Zaremba, Anne, Hegenbarth, Silke, Kurts, Christian, Beyer, Marc, Schultze, Joachim L., Kastenmüller, Wolfgang, Rose-John, Stefan, Knolle, Percy A.
Published in Cell reports (Cambridge) (11.09.2014)
Published in Cell reports (Cambridge) (11.09.2014)
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PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function
Morotti, Matteo, Grimm, Alizee J., Hope, Helen Carrasco, Arnaud, Marion, Desbuisson, Mathieu, Rayroux, Nicolas, Barras, David, Masid, Maria, Murgues, Baptiste, Chap, Bovannak S., Ongaro, Marco, Rota, Ioanna A., Ronet, Catherine, Minasyan, Aspram, Chiffelle, Johanna, Lacher, Sebastian B., Bobisse, Sara, Murgues, Clément, Ghisoni, Eleonora, Ouchen, Khaoula, Bou Mjahed, Ribal, Benedetti, Fabrizio, Abdellaoui, Naoill, Turrini, Riccardo, Gannon, Philippe O., Zaman, Khalil, Mathevet, Patrice, Lelievre, Loic, Crespo, Isaac, Conrad, Marcus, Verdeil, Gregory, Kandalaft, Lana E., Dagher, Julien, Corria-Osorio, Jesus, Doucey, Marie-Agnes, Ho, Ping-Chih, Harari, Alexandre, Vannini, Nicola, Böttcher, Jan P., Dangaj Laniti, Denarda, Coukos, George
Published in Nature (London) (09.05.2024)
Published in Nature (London) (09.05.2024)
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Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
Zelenay, Santiago, van der Veen, Annemarthe G., Böttcher, Jan P., Snelgrove, Kathryn J., Rogers, Neil, Acton, Sophie E., Chakravarty, Probir, Girotti, Maria Romina, Marais, Richard, Quezada, Sergio A., Sahai, Erik, Reis e Sousa, Caetano
Published in Cell (10.09.2015)
Published in Cell (10.09.2015)
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Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity
Böttcher, Jan P., Schanz, Oliver, Wohlleber, Dirk, Abdullah, Zeinab, Debey-Pascher, Svenja, Staratschek-Jox, Andrea, Höchst, Bastian, Hegenbarth, Silke, Grell, Jessica, Limmer, Andreas, Atreya, Imke, Neurath, Markus F., Busch, Dirk H., Schmitt, Edgar, van Endert, Peter, Kolanus, Waldemar, Kurts, Christian, Schultze, Joachim L., Diehl, Linda, Knolle, Percy A.
Published in Cell reports (Cambridge) (28.03.2013)
Published in Cell reports (Cambridge) (28.03.2013)
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Validation of biplane high-speed fluoroscopy combined with two different noninvasive tracking methodologies for measuring in vivo distal limb kinematics of the horse
Geiger, S M, Reich, E, Böttcher, P, Grund, S, Hagen, J
Published in Equine veterinary journal (01.03.2018)
Published in Equine veterinary journal (01.03.2018)
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Journal Article
Distinct kinetics and dynamics of cross‐presentation in liver sinusoidal endothelial cells compared to dendritic cells
Schurich, Anna, Böttcher, Jan P., Burgdorf, Sven, Penzler, Patrick, Hegenbarth, Silke, Kern, Michaela, Dolf, Andreas, Endl, Elmar, Schultze, Joachim, Wiertz, Emmanuel, Stabenow, Dirk, Kurts, Christian, Knolle, Percy
Published in Hepatology (Baltimore, Md.) (01.09.2009)
Published in Hepatology (Baltimore, Md.) (01.09.2009)
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Mechanisms balancing tolerance and immunity in the liver
Böttcher, Jan P, Knolle, Percy A, Stabenow, Dirk
Published in Digestive diseases (Basel) (01.01.2011)
Published in Digestive diseases (Basel) (01.01.2011)
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10.01 Prostanoid-insensitive chimeric antigen receptor modified T cells mediate therapeutic efficacy in solid cancer models
Dörr, J, Gregor, L, Lacher, SB, Öner, A, Lesch, S, Michaelides, S, Majed, L, Fertig, L, Carlini, E, Andreu Sanz, D, Briukhovetska, D, Stock, S, Gottschlich, A, Böttcher, JP, Kobold, S
Published in Journal for immunotherapy of cancer (01.03.2024)
Published in Journal for immunotherapy of cancer (01.03.2024)
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NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
Böttcher, Jan P., Bonavita, Eduardo, Chakravarty, Probir, Blees, Hanna, Cabeza-Cabrerizo, Mar, Sammicheli, Stefano, Rogers, Neil C., Sahai, Erik, Zelenay, Santiago, Reis e Sousa, Caetano
Published in Cell (22.02.2018)
Published in Cell (22.02.2018)
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Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection
Abdullah, Zeinab, Geiger, Sergej, Nino-Castro, Andrea, Böttcher, Jan P, Muraliv, Eugenia, Gaidt, Moritz, Schildberg, Frank A, Riethausen, Kati, Flossdorf, Juliane, Krebs, Wolfgang, Chakraborty, Trinad, Kurts, Christian, Schultze, Joachim L, Knolle, Percy A, Klotz, Luisa
Published in PloS one (21.05.2012)
Published in PloS one (21.05.2012)
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Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Dudek, Michael, Pfister, Dominik, Donakonda, Sainitin, Filpe, Pamela, Schneider, Annika, Laschinger, Melanie, Hartmann, Daniel, Hüser, Norbert, Meiser, Philippa, Bayerl, Felix, Inverso, Donato, Wigger, Jennifer, Sebode, Marcial, Öllinger, Rupert, Rad, Roland, Hegenbarth, Silke, Anton, Martina, Guillot, Adrien, Bowman, Andrew, Heide, Danijela, Müller, Florian, Ramadori, Pierluigi, Leone, Valentina, Garcia-Caceres, Cristina, Gruber, Tim, Seifert, Gabriel, Kabat, Agnieszka M., Mallm, Jan-Philipp, Reider, Simon, Effenberger, Maria, Roth, Susanne, Billeter, Adrian T., Müller-Stich, Beat, Pearce, Edward J., Koch-Nolte, Friedrich, Käser, Rafael, Tilg, Herbert, Thimme, Robert, Boettler, Tobias, Tacke, Frank, Dufour, Jean-Francois, Haller, Dirk, Murray, Peter J., Heeren, Ron, Zehn, Dietmar, Böttcher, Jan P., Heikenwälder, Mathias, Knolle, Percy A.
Published in Nature (London) (15.04.2021)
Published in Nature (London) (15.04.2021)
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