NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
Böttcher, Jan P., Bonavita, Eduardo, Chakravarty, Probir, Blees, Hanna, Cabeza-Cabrerizo, Mar, Sammicheli, Stefano, Rogers, Neil C., Sahai, Erik, Zelenay, Santiago, Reis e Sousa, Caetano
Published in Cell (22.02.2018)
Published in Cell (22.02.2018)
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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection
Flommersfeld, Sophie, Böttcher, Jan P., Ersching, Jonatan, Flossdorf, Michael, Meiser, Philippa, Pachmayr, Ludwig O., Leube, Justin, Hensel, Inge, Jarosch, Sebastian, Zhang, Qin, Chaudhry, M. Zeeshan, Andrae, Immanuel, Schiemann, Matthias, Busch, Dirk.H., Cicin-Sain, Luka, Sun, Joseph C., Gasteiger, Georg, Victora, Gabriel D., Höfer, Thomas, Buchholz, Veit R., Grassmann, Simon
Published in Immunity (Cambridge, Mass.) (12.10.2021)
Published in Immunity (Cambridge, Mass.) (12.10.2021)
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Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Dudek, Michael, Pfister, Dominik, Donakonda, Sainitin, Filpe, Pamela, Schneider, Annika, Laschinger, Melanie, Hartmann, Daniel, Hüser, Norbert, Meiser, Philippa, Bayerl, Felix, Inverso, Donato, Wigger, Jennifer, Sebode, Marcial, Öllinger, Rupert, Rad, Roland, Hegenbarth, Silke, Anton, Martina, Guillot, Adrien, Bowman, Andrew, Heide, Danijela, Müller, Florian, Ramadori, Pierluigi, Leone, Valentina, Garcia-Caceres, Cristina, Gruber, Tim, Seifert, Gabriel, Kabat, Agnieszka M., Mallm, Jan-Philipp, Reider, Simon, Effenberger, Maria, Roth, Susanne, Billeter, Adrian T., Müller-Stich, Beat, Pearce, Edward J., Koch-Nolte, Friedrich, Käser, Rafael, Tilg, Herbert, Thimme, Robert, Boettler, Tobias, Tacke, Frank, Dufour, Jean-Francois, Haller, Dirk, Murray, Peter J., Heeren, Ron, Zehn, Dietmar, Böttcher, Jan P., Heikenwälder, Mathias, Knolle, Percy A.
Published in Nature (London) (15.04.2021)
Published in Nature (London) (15.04.2021)
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PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function
Morotti, Matteo, Grimm, Alizee J., Hope, Helen Carrasco, Arnaud, Marion, Desbuisson, Mathieu, Rayroux, Nicolas, Barras, David, Masid, Maria, Murgues, Baptiste, Chap, Bovannak S., Ongaro, Marco, Rota, Ioanna A., Ronet, Catherine, Minasyan, Aspram, Chiffelle, Johanna, Lacher, Sebastian B., Bobisse, Sara, Murgues, Clément, Ghisoni, Eleonora, Ouchen, Khaoula, Bou Mjahed, Ribal, Benedetti, Fabrizio, Abdellaoui, Naoill, Turrini, Riccardo, Gannon, Philippe O., Zaman, Khalil, Mathevet, Patrice, Lelievre, Loic, Crespo, Isaac, Conrad, Marcus, Verdeil, Gregory, Kandalaft, Lana E., Dagher, Julien, Corria-Osorio, Jesus, Doucey, Marie-Agnes, Ho, Ping-Chih, Harari, Alexandre, Vannini, Nicola, Böttcher, Jan P., Dangaj Laniti, Denarda, Coukos, George
Published in Nature (London) (09.05.2024)
Published in Nature (London) (09.05.2024)
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A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity
Meiser, Philippa, Knolle, Moritz A., Hirschberger, Anna, de Almeida, Gustavo P., Bayerl, Felix, Lacher, Sebastian, Pedde, Anna-Marie, Flommersfeld, Sophie, Hönninger, Julian, Stark, Leonhard, Stögbauer, Fabian, Anton, Martina, Wirth, Markus, Wohlleber, Dirk, Steiger, Katja, Buchholz, Veit R., Wollenberg, Barbara, Zielinski, Christina E., Braren, Rickmer, Rueckert, Daniel, Knolle, Percy A., Kaissis, Georgios, Böttcher, Jan P.
Published in Cancer cell (14.08.2023)
Published in Cancer cell (14.08.2023)
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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
Bayerl, Felix, Meiser, Philippa, Donakonda, Sainitin, Hirschberger, Anna, Lacher, Sebastian B., Pedde, Anna-Marie, Hermann, Chris D., Elewaut, Anais, Knolle, Moritz, Ramsauer, Lukas, Rudolph, Thomas J., Grassmann, Simon, Öllinger, Rupert, Kirchhammer, Nicole, Trefny, Marcel, Anton, Martina, Wohlleber, Dirk, Höchst, Bastian, Zaremba, Anne, Krüger, Achim, Rad, Roland, Obenauf, Anna C., Schadendorf, Dirk, Zippelius, Alfred, Buchholz, Veit R., Schraml, Barbara U., Böttcher, Jan P.
Published in Immunity (Cambridge, Mass.) (13.06.2023)
Published in Immunity (Cambridge, Mass.) (13.06.2023)
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Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens
Schulz, Oliver, Hanč, Pavel, Böttcher, Jan P., Hoogeboom, Robbert, Diebold, Sandra S., Tolar, Pavel, Reis e Sousa, Caetano
Published in Cell reports (Cambridge) (10.07.2018)
Published in Cell reports (Cambridge) (10.07.2018)
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Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics
Zenke, Simon, Palm, Margriet M., Braun, Julia, Gavrilov, Alina, Meiser, Philippa, Böttcher, Jan P., Beyersdorf, Niklas, Ehl, Stephan, Gerard, Audrey, Lämmermann, Tim, Schumacher, Ton N., Beltman, Joost B., Rohr, Jan C.
Published in Immunity (Cambridge, Mass.) (18.02.2020)
Published in Immunity (Cambridge, Mass.) (18.02.2020)
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IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function
Böttcher, Jan P., Schanz, Oliver, Garbers, Christoph, Zaremba, Anne, Hegenbarth, Silke, Kurts, Christian, Beyer, Marc, Schultze, Joachim L., Kastenmüller, Wolfgang, Rose-John, Stefan, Knolle, Percy A.
Published in Cell reports (Cambridge) (11.09.2014)
Published in Cell reports (Cambridge) (11.09.2014)
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Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods
Bayerl, Felix, Bejarano, David A, Bertacchi, Giulia, Doffin, Anne-Claire, Gobbini, Elisa, Hubert, Margaux, Li, Lijian, Meiser, Philippa, Pedde, Anna-Marie, Posch, Wilfried, Rupp, Luise, Schlitzer, Andreas, Schmitz, Marc, Schraml, Barbara U, Uderhardt, Stefan, Valladeau-Guilemond, Jenny, Wilflingseder, Doris, Zaderer, Viktoria, Böttcher, Jan P
Published in European journal of immunology (01.11.2023)
Published in European journal of immunology (01.11.2023)
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RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids
Abdullah, Zeinab, Schlee, Martin, Roth, Susanne, Mraheil, Mobarak Abu, Barchet, Winfried, Böttcher, Jan, Hain, Torsten, Geiger, Sergej, Hayakawa, Yoshihiro, Fritz, Jörg H, Civril, Filiz, Hopfner, Karl-Peter, Kurts, Christian, Ruland, Jürgen, Hartmann, Gunther, Chakraborty, Trinad, Knolle, Percy A
Published in The EMBO journal (05.11.2012)
Published in The EMBO journal (05.11.2012)
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Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
Zelenay, Santiago, van der Veen, Annemarthe G., Böttcher, Jan P., Snelgrove, Kathryn J., Rogers, Neil, Acton, Sophie E., Chakravarty, Probir, Girotti, Maria Romina, Marais, Richard, Quezada, Sergio A., Sahai, Erik, Reis e Sousa, Caetano
Published in Cell (10.09.2015)
Published in Cell (10.09.2015)
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PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells
Lacher, Sebastian B., Dörr, Janina, de Almeida, Gustavo P., Hönninger, Julian, Bayerl, Felix, Hirschberger, Anna, Pedde, Anna-Marie, Meiser, Philippa, Ramsauer, Lukas, Rudolph, Thomas J., Spranger, Nadine, Morotti, Matteo, Grimm, Alizee J., Jarosch, Sebastian, Oner, Arman, Gregor, Lisa, Lesch, Stefanie, Michaelides, Stefanos, Fertig, Luisa, Briukhovetska, Daria, Majed, Lina, Stock, Sophia, Busch, Dirk H., Buchholz, Veit R., Knolle, Percy A., Zehn, Dietmar, Dangaj Laniti, Denarda, Kobold, Sebastian, Böttcher, Jan P.
Published in Nature (London) (09.05.2024)
Published in Nature (London) (09.05.2024)
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B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
Afzali, Ali Maisam, Nirschl, Lucy, Sie, Christopher, Pfaller, Monika, Ulianov, Oleksii, Hassler, Tobias, Federle, Christine, Petrozziello, Elisabetta, Kalluri, Sudhakar Reddy, Chen, Hsin Hsiang, Tyystjärvi, Sofia, Muschaweckh, Andreas, Lammens, Katja, Delbridge, Claire, Büttner, Andreas, Steiger, Katja, Seyhan, Gönül, Ottersen, Ole Petter, Öllinger, Rupert, Rad, Roland, Jarosch, Sebastian, Straub, Adrian, Mühlbauer, Anton, Grassmann, Simon, Hemmer, Bernhard, Böttcher, Jan P., Wagner, Ingrid, Kreutzfeldt, Mario, Merkler, Doron, Pardàs, Irene Bonafonte, Schmidt Supprian, Marc, Buchholz, Veit R., Heink, Sylvia, Busch, Dirk H., Klein, Ludger, Korn, Thomas
Published in Nature (London) (14.03.2024)
Published in Nature (London) (14.03.2024)
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Counterpropagating topological and quantum Hall edge channels
Shamim, Saquib, Shekhar, Pragya, Beugeling, Wouter, Böttcher, Jan, Budewitz, Andreas, Mayer, Julian-Benedikt, Lunczer, Lukas, Hankiewicz, Ewelina M., Buhmann, Hartmut, Molenkamp, Laurens W.
Published in Nature communications (13.05.2022)
Published in Nature communications (13.05.2022)
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A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection
Bosch, Miriam, Kallin, Nina, Donakonda, Sainitin, Zhang, Jitao David, Wintersteller, Hannah, Hegenbarth, Silke, Heim, Kathrin, Ramirez, Carlos, Fürst, Anna, Lattouf, Elias Isaac, Feuerherd, Martin, Chattopadhyay, Sutirtha, Kumpesa, Nadine, Griesser, Vera, Hoflack, Jean-Christophe, Siebourg-Polster, Juliane, Mogler, Carolin, Swadling, Leo, Pallett, Laura J., Meiser, Philippa, Manske, Katrin, de Almeida, Gustavo P., Kosinska, Anna D., Sandu, Ioana, Schneider, Annika, Steinbacher, Vincent, Teng, Yan, Schnabel, Julia, Theis, Fabian, Gehring, Adam J., Boonstra, Andre, Janssen, Harry L. A., Vandenbosch, Michiel, Cuypers, Eva, Öllinger, Rupert, Engleitner, Thomas, Rad, Roland, Steiger, Katja, Oxenius, Annette, Lo, Wan-Lin, Klepsch, Victoria, Baier, Gottfried, Holzmann, Bernhard, Maini, Mala K., Heeren, Ron, Murray, Peter J., Thimme, Robert, Herrmann, Carl, Protzer, Ulrike, Böttcher, Jan P., Zehn, Dietmar, Wohlleber, Dirk, Lauer, Georg M., Hofmann, Maike, Luangsay, Souphalone, Knolle, Percy A.
Published in Nature (London) (25.07.2024)
Published in Nature (London) (25.07.2024)
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Laboratory Findings, Compassionate Use of Favipiravir, and Outcome in Patients With Ebola Virus Disease, Guinea, 2015-A Retrospective Observational Study
Kerber, Romy, Lorenz, Eva, Duraffour, Sophie, Sissoko, Daouda, Rudolf, Martin, Jaeger, Anna, Cisse, Sekou Ditinn, Camara, Alseny-Modet, Miranda, Osvaldo, Castro, Carlos M, Akoi Bore, Joseph, Raymond Koundouno, Fara, Repits, Johanna, Afrough, Babak, Becker-Ziaja, Beate, Hinzmann, Julia, Mertens, Marc, Vitoriano, Ines, Hugh Logue, Christopher, Böttcher, Jan-Peter, Pallasch, Elisa, Sachse, Andreas, Bah, Amadou, Cabeza-Cabrerizo, Mar, Nitzsche, Katja, Kuisma, Eeva, Michel, Janine, Holm, Tobias, Zekeng, Elsa Gayle, Cowley, Lauren A, Garcia-Dorival, Isabel, Hetzelt, Nicole, Baum, Jonathan Hans Josef, Portmann, Jasmine, Carter, Lisa, Yenamaberhan, Rahel Lemma, Camino, Alvaro, Enkirch, Theresa, Singethan, Katrin, Meisel, Sarah, Mazzarelli, Antonio, Kosgei, Abigail, Kafetzopoulou, Liana, Rickett, Natasha Y, Patrono, Livia Victoria, Ghebreghiorghis, Luam, Arnold, Ulrike, Colin, Géraldine, Juchet, Sylvain, Marchal, Claire Levy, Kolie, Jacques Seraphin, Beavogui, Abdoul Habib, Wurr, Stephanie, Bockholt, Sabrina, Krumkamp, Ralf, May, Jürgen, Stoecker, Kilian, Fleischmann, Erna, Ippolito, Giuseppe, Carroll, Miles W, Koivogui, Lamine, Magassouba, N'Faly, Keita, Sakoba, Gurry, Céline, Drury, Patrick, Diallo, Boubacar, Formenty, Pierre, Wölfel, Roman, Di Caro, Antonino, Gabriel, Martin, Anglaret, Xavier, Malvy, Denis, Günther, Stephan
Published in The Journal of infectious diseases (19.06.2019)
Published in The Journal of infectious diseases (19.06.2019)
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Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity
Böttcher, Jan P., Schanz, Oliver, Wohlleber, Dirk, Abdullah, Zeinab, Debey-Pascher, Svenja, Staratschek-Jox, Andrea, Höchst, Bastian, Hegenbarth, Silke, Grell, Jessica, Limmer, Andreas, Atreya, Imke, Neurath, Markus F., Busch, Dirk H., Schmitt, Edgar, van Endert, Peter, Kolanus, Waldemar, Kurts, Christian, Schultze, Joachim L., Diehl, Linda, Knolle, Percy A.
Published in Cell reports (Cambridge) (28.03.2013)
Published in Cell reports (Cambridge) (28.03.2013)
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