Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial
Garcia-Manero, Guillermo, Dr Prof, Fenaux, Pierre, Prof, Al-Kali, Aref, MD, Baer, Maria R, Prof, Sekeres, Mikkael A, Prof, Roboz, Gail J, Prof, Gaidano, Gianluca, Prof, Scott, Bart L, MD, Greenberg, Peter, Prof, Platzbecker, Uwe, Prof, Steensma, David P, MD, Kambhampati, Suman, MD, Kreuzer, Karl-Anton, Prof, Godley, Lucy A, Prof, Atallah, Ehab, MD, Collins, Robert, Prof, Kantarjian, Hagop, Prof, Jabbour, Elias, MD, Wilhelm, Francois E, MD, Azarnia, Nozar, PhD, Silverman, Lewis R, MD
Published in The lancet oncology (01.04.2016)
Published in The lancet oncology (01.04.2016)
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Journal Article
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
Bonner, James A, Harari, Paul M, Giralt, Jordi, Azarnia, Nozar, Shin, Dong M, Cohen, Roger B, Jones, Christopher U, Sur, Ranjan, Raben, David, Jassem, Jacek, Ove, Roger, Kies, Merrill S, Baselga, Jose, Youssoufian, Hagop, Amellal, Nadia, Rowinsky, Eric K, Ang, K. Kian
Published in The New England journal of medicine (09.02.2006)
Published in The New England journal of medicine (09.02.2006)
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Multicenter Phase II and Translational Study of Cetuximab in Metastatic Colorectal Carcinoma Refractory to Irinotecan, Oxaliplatin, and Fluoropyrimidines
Lenz, Heinz-Josef, Van Cutsem, Eric, Khambata-Ford, Shirin, Mayer, Robert J, Gold, Philip, Stella, Philip, Mirtsching, Barry, Cohn, Allen L, Pippas, Andrew W, Azarnia, Nozar, Tsuchihashi, Zenta, Mauro, David J, Rowinsky, Eric K
Published in Journal of clinical oncology (20.10.2006)
Published in Journal of clinical oncology (20.10.2006)
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Journal Article
Phase II Multicenter Study of the Epidermal Growth Factor Receptor Antibody Cetuximab and Cisplatin for Recurrent and Refractory Squamous Cell Carcinoma of the Head and Neck
HERBST, Roy S, ARQUETTE, Matthew, SHIN, Dong M, DICKE, Karel, VOKES, Everett E, AZARNIA, Nozar, WAUN KI HONG, KIES, Merrill S
Published in Journal of clinical oncology (20.08.2005)
Published in Journal of clinical oncology (20.08.2005)
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Journal Article
Validation of a post-hypomethylating agent failure prognostic model in myelodysplastic syndromes patients treated in a randomized controlled phase III trial of rigosertib vs. best supportive care
Nazha, Aziz, Sekeres, Mikkael A, Komrokji, Rami, Steensma, David P, Kantarjian, Hagop, Roboz, Gail, Fenaux, Pierre, Prebet, Thomas, Azarnia, Nozar, Zbyszewski, Patrick S, Fruchtman, Steven M, Santini, Valeria, Silverman, Lewis R, Platzbecker, Uwe, Garcia-Manero, Guillermo
Published in Blood cancer journal (New York) (14.12.2017)
Published in Blood cancer journal (New York) (14.12.2017)
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Journal Article
Phase II Trial of Liposome-Encapsulated Doxorubicin, Cyclophosphamide, and Fluorouracil as First-Line Therapy in Patients With Metastatic Breast Cancer
VALERO, V, BUZDAR, A. U, BOOSER, D, LEE, L. W, HORTOBAGYI, G. N, THERIAULT, R. L, AZARNIA, N, FONSECA, G. A, WILLEY, J, EWER, M, WALTERS, R. S, MACKAY, B, PODOLOFF, D
Published in Journal of clinical oncology (01.05.1999)
Published in Journal of clinical oncology (01.05.1999)
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Journal Article
AIDS-related Kaposi’s Sarcoma: A Phase II Study of Liposomal Doxorubicin
Tony W. Cheung, Scot C. Remick, Nozar Azarnia, Jo Ann Proper, Jose R. Barrueco, Bruce J. Dezube
Published in Clinical cancer research (01.11.1999)
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Published in Clinical cancer research (01.11.1999)
Journal Article
Phase 3, Multi-Center, International, Randomized, Double-Blind, Placebo Controlled Study of Oral Rigosertib + Injectable Azacitidine (AZA) Versus Injectable Azacitidine in Treatment-Naive Patients with Higher-Risk Myelodysplastic Syndrome (HR-MDS)
Garcia-Manero, Guillermo, Navada, Shyamala C., Fenaux, Pierre, Zbyszewski, Patrick S., Adesanya, Afoluso Ronnee, Azarnia, Nozar, Fruchtman, Steven M., Silverman, Lewis R.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
The Inspire Study in Higher-Risk Myelodysplastic Syndrome (HR-MDS): A Novel Phase 3 Study Adaptive Design for Hematological Malignancies in Adults
Jonasova, Anna, Luger, Selina M., Al-Kali, Aref, Valcarcel, David, Woodman, Richard C., Adesanya, Afoluso Ronnee, Azarnia, Nozar, Parris, Matthew, Warlick, Erica D., Jedrzejczak, Wieslaw W., Díez-Campelo, María, Garcia-Manero, Guillermo
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Age Distribution and Pattern of Myeloid Marrow Mutations in Patients (pts) with Higher-Risk Myelodysplastic Syndromes (HR-MDS) after Failure of Hypomethylating Agents (HMAs)
Mufti, Ghulam J, Silverman, Lewis R., Best, Steven, Fructman, Steve, Azarnia, Nozar, Petrone, Michael E., Garcia-Manero, Guillermo
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Improved anti-tumor response rate with decreased cardiotoxicity of non-pegylated liposomal doxorubicin compared with conventional doxorubicin in first-line treatment of metastatic breast cancer in patients who had received prior adjuvant doxorubicin: results of a retrospective analysis
Batist, Gerald, Harris, Lyndsay, Azarnia, Nozar, Lee, Lily Waiyee, Daza-Ramirez, Pascual
Published in Anti-cancer drugs (01.06.2006)
Published in Anti-cancer drugs (01.06.2006)
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Journal Article
Mutational Profile and Karyotypic Abnormalities of a Cohort of Clinical Trial Patients with Higher-Risk Myelodysplastic Syndromes (MDS) Following Failure of Hypomethylating Agents (HMAs): Impact on Response to Rigosertib Therapy
Mufti, Ghulam J, Best, Steven, Lea, Nicholas, Silverman, Lewis R., Garcia-Manero, Guillermo, Azarnia, Nozar, Wilhelm, Francois, Goehring, Gudrun
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Computational Analysis of Genomic Abnormalities from a Phase 3 Trial of Rigosertib in Higher-Risk MDS: Simulation of a Predictive Signature for Clinical Response
Garcia-Manero, Guillermo, Petrone, Michael E., Fruchtman, Steven M., Brownstein, Bernard, Loferer, Hannes, Azarnia, Nozar, Vali, Shireen, Singh, Neeraj Kumar, Usmani, Shahabuddin, Grover, Himanshu, Abbasi, Taher, Silverman, Lewis R.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Liposome‐encapsulated doxorubicin compared with conventional doxorubicin in a randomized multicenter trial as first‐line therapy of metastatic breast carcinoma
Harris, Lyndsay, Batist, Gerald, Belt, Robert, Rovira, Douglas, Navari, Rudolph, Azarnia, Nozar, Welles, Lauri, Winer, Eric
Published in Cancer (01.01.2002)
Published in Cancer (01.01.2002)
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Journal Article
A Phase II Study of the Combination of Oral Rigosertib and Azacitidine in Patients with Myelodysplastic Syndromes (MDS)
Navada, Shyamala C., Silverman, Lewis R., Hearn, Katherine P., Odchimar-Reissig, Rosalie, Demakos, Erin P., Alvarado, Yesid, Daver, Naval, DiNardo, Courtney, Konopleva, Marina, Borthakur, Gautam, Pemmaraju, Naveen, Kadia, Tapan, Fenaux, Pierre, Fruchtman, Steve, Azarnia, Nozar, Garcia-Manero, Guillermo
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Correlation of overall survival (OS) with bone marrow blast (BMBL) response in patients (pts) with myelodysplastic syndrome
Silverman, Lewis R., Fenaux, Pierre, Greenberg, Peter, Demakos, Erin P, Santini, Valeria, Seymour, John Francis, Navada, Shyamala Chendal, Petrone, Michael E., Snyder, Barbara R, Azarnia, Nozar, Garcia-Manero, Guillermo
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
INSPIRE: A randomized phase III trial of intravenous rigosertib in patients with higher-risk myelodysplastic syndromes (HR-MDS) after failure of hypomethylating agents (HMAs)—Study design informed by subgroup analyses of ONTIME
Garcia-Manero, Guillermo, Al-Kali, Aref, Baer, Maria R., Roboz, Gail J., Platzbecker, Uwe, Kambhampati, Suman, Godley, Lucy A., Collins, Robert, Shammo, Jamile M., Santini, Valeria, Raza, Dr. Azra, Silverman, Lewis R., Azarnia, Nozar, Fruchtman, Steven M., Snyder, Barbara R, Fenaux, Pierre
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
A Phase I/II Study of the Combination of Oral Rigosertib and Azacitidine in Patients with Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)
Navada, Shyamala C., Garcia-Manero, Guillermo, Wilhelm, Francois, Hearn, Katherine, Odchimar-Reissig, Rosalie, Demakos, Erin P., Alvarado, Yesid, Daver, Naval, DiNardo, Courtney D., Konopleva, Marina, Borthakur, Gautam, Azarnia, Nozar, Silverman, Lewis R.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Overall survival (OS) and baseline disease characteristics in MDS patients with primary HMA failure in a randomized, controlled, phase III study of rigosertib
Fenaux, Pierre, Al-Kali, Aref, Baer, Maria R., Sekeres, Mikkael A., Roboz, Gail J., Gaidano, Gianluca, Silverman, Lewis R., Scott, Bart L, Greenberg, Peter, Platzbecker, Uwe, Steensma, David P., Kreuzer, Karl A, Godley, Lucy A., Collins, Robert, Atallah, Ehab L., Azarnia, Nozar, Garcia-Manero, Guillermo
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
Prognostic and predictive value of IPSS-R in assessing overall survival (OS) in a phase III study of rigosertib in second-line higher-risk (HR) MDS patients
Silverman, Lewis R., Fenaux, Pierre, Al-Kali, Aref, Baer, Maria R., Sekeres, Mikkael A., Roboz, Gail J., Gaidano, Gianluca, Scott, Bart L, Greenberg, Peter, Platzbecker, Uwe, Steensma, David P., Kreuzer, Karl A, Godley, Lucy A., Collins, Robert, Atallah, Ehab L., Azarnia, Nozar, Garcia-Manero, Guillermo
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article