The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia
Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Cortés, Roldán, Cunningham, Alan, Pruis, Maurien G., de Boer, Bauke, van den Heuvel, Fiona A. J., Geugien, Marjan, Wierenga, Albertus T. J., Brouwers-Vos, Annet Z., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob
Published in Nature communications (01.03.2022)
Published in Nature communications (01.03.2022)
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Journal Article
Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
Vilaplana-Lopera, Nuria, Cuminetti, Vincent, Almaghrabi, Ruba, Papatzikas, Grigorios, Rout, Ashok Kumar, Jeeves, Mark, González, Elena, Alyahyawi, Yara, Cunningham, Alan, Erdem, Ayşegül, Schnütgen, Frank, Raghavan, Manoj, Potluri, Sandeep, Cazier, Jean-Baptiste, Schuringa, Jan Jacob, Reed, Michelle A C, Arranz, Lorena, Günther, Ulrich L, Garcia, Paloma
Published in eLife (02.09.2022)
Published in eLife (02.09.2022)
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Journal Article
Clinical characteristics and outcomes of nosocomial COVID-19 in Turkey: A retrospective multicenter study
Yıldırım, Süleyman, Yılmaz, Celalettin, Polat, Gülru, Baris, Serap, Başyiğit, İlknur, Kaya, İlknur, Anar, Ceyda, Bozkurt, Mihriban, Baykal, Hüsnü, Dirol, Hulya, Ozbey, Gamzenur, Ozsari, Emine, Cireli, Emel, Çıirak, Ali, Tatar, Dursun, Gayaf, Mine, Karaoglanoglu, Selen, Aydin, Yener, Eroglu, Atilla, Olçar, Yıldız, Yıldırım, Berna, Gürsoy, Bengül, Yılmaz, Deniz, Niksarlioglu, Elif, Eren, Ramazan, Erdem, Ayşegül, Tor, Müge, Fakili, Fusun, Çolak, Mustafa, Erçelik, Merve, Tabaru, Ali, Ediboglu, Özlem
Published in Asian Pacific journal of tropical medicine (01.08.2023)
Published in Asian Pacific journal of tropical medicine (01.08.2023)
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Journal Article
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability
Erdem, Ayşegül, Marin, Silvia, Pereira-Martins, Diego A., Geugien, Marjan, Cunningham, Alan, Pruis, Maurien G., Weinhäuser, Isabel, Gerding, Albert, Bakker, Barbara M., Wierenga, Albertus T. J., Rego, Eduardo M., Huls, Gerwin, Cascante, Marta, Schuringa, Jan Jacob
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Journal Article
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors
Horton, Sarah J., Giotopoulos, George, Yun, Haiyang, Vohra, Shabana, Sheppard, Olivia, Bashford-Rogers, Rachael, Rashid, Mamunur, Clipson, Alexandra, Chan, Wai-In, Sasca, Daniel, Yiangou, Loukia, Osaki, Hikari, Basheer, Faisal, Gallipoli, Paolo, Burrows, Natalie, Erdem, Ayşegül, Sybirna, Anastasiya, Foerster, Sarah, Zhao, Wanfeng, Sustic, Tonci, Petrunkina Harrison, Anna, Laurenti, Elisa, Okosun, Jessica, Hodson, Daniel, Wright, Penny, Smith, Ken G., Maxwell, Patrick, Fitzgibbon, Jude, Du, Ming Q., Adams, David J., Huntly, Brian J. P.
Published in Nature cell biology (01.09.2017)
Published in Nature cell biology (01.09.2017)
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Journal Article
Short carbon fiber reinforced poly(lactic acid) and its thermoplastic polyurethane blends: The effect of carbon fiber, polyurethane, and compatibilizer amounts
Arslan, Çağrıalp, Erdem, Ayşegül, Özmen, Özkan, Tayfun, Ümit, Doğan, Mehmet
Published in Journal of vinyl & additive technology (05.09.2024)
Published in Journal of vinyl & additive technology (05.09.2024)
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Journal Article
Dietary methionine starvation impairs acute myeloid leukemia progression
Cunningham, Alan, Erdem, Ayşegül, Alshamleh, Islam, Geugien, Marjan, Pruis, Maurien, Pereira-Martins, Diego Antonio, van den Heuvel, Fiona A. J., Wierenga, Albertus T. J., ten Berge, Hilde, Dennebos, Robin, van den Boom, Vincent, Hogeling, Shanna M., Weinhäuser, Isabel, Knops, Ruth, de Blaauw, Pim, Heiner-Fokkema, M. Rebecca, Woolthuis, Carolien, Günther, Ulrich L., Rego, Eduardo M., Martens, Joost H. A., Jansen, Joop H., Schwalbe, Harald, Huls, Gerwin, Schuringa, Jan Jacob
Published in Blood (10.11.2022)
Published in Blood (10.11.2022)
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Journal Article
Metabolic crosstalk between stromal and malignant cells in the bone marrow niche
Tirado, Hernán A., Balasundaram, Nithya, Laaouimir, Lotfi, Erdem, Ayşegül, van Gastel, Nick
Published in Bone Reports (01.06.2023)
Published in Bone Reports (01.06.2023)
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Journal Article
Production and Characterization of Flame Retardant Leather Waste Filled Thermoplastic Polyurethane
Ustuntag, Sumeyye, Cakir, Nida, Erdem, Aysegul, Ozmen, Ozkan, Dogan, Mehmet
Published in ACS omega (27.02.2024)
Published in ACS omega (27.02.2024)
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Journal Article
The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia
Cunningham, Alan, Oudejans, Lieve L, Geugien, Marjan, Pereira-Martins, Diego Antonio, Wierenga, Albertus T J, Erdem, Ayşegül, Sternadt, Dominique, Huls, Gerwin, Schuringa, Jan Jacob
Published in Blood advances (09.01.2024)
Published in Blood advances (09.01.2024)
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Journal Article
HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells
Wierenga, Albertus T J, Cunningham, Alan, Erdem, Ayşegül, Lopera, Nuria Vilaplana, Brouwers-Vos, Annet Z, Pruis, Maurien, Mulder, André B, Günther, Ulrich L, Martens, Joost H A, Vellenga, Edo, Schuringa, Jan Jacob
Published in Cancer & metabolism (27.12.2019)
Published in Cancer & metabolism (27.12.2019)
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Journal Article
Comparative Transcriptomic Analyses of Peripheral Blood Mononuclear Cells of COVID-19 Patients without Pneumonia and with Severe Pneumonia in the First Year of Follow-Up
Kayalar, Ozgecan, Cetinkaya, Pelin Duru, Eldem, Vahap, Argun Baris, Serap, Kokturk, Nurdan, Kuralay, Selim Can, Rajabi, Hadi, Konyalilar, Nur, Mortazavi, Deniz, Korkunc, Seval Kubra, Erkan, Sinem, Aksoy, Gizem Tuşe, Eyikudamaci, Gul, Pinar Deniz, Pelin, Baydar Toprak, Oya, Yildiz Gulhan, Pinar, Sagcan, Gulseren, Kose, Neslihan, Tomruk Erdem, Aysegul, Fakili, Fusun, Ozturk, Onder, Basyigit, Ilknur, Boyaci, Hasim, Azak, Emel, Ulukavak Ciftci, Tansu, Oguzulgen, Ipek Kivilcim, Ozger, Hasan Selcuk, Aysert Yildiz, Pinar, Hanta, Ismail, Ataoglu, Ozlem, Ercelik, Merve, Cuhadaroglu, Caglar, Okur, Hacer Kuzu, Tor, Muge Meltem, Nurlu Temel, Esra, Kul, Seval, Tutuncu, Yıldız, Itil, Oya, Bayram, Hasan
Published in Viruses (28.07.2024)
Published in Viruses (28.07.2024)
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Journal Article
Clinicopathological profile of gastrointestinal tuberculosis: a multinational ID-IRI study
Tanoglu, Alpaslan, Erdem, Hakan, Friedland, Jon S., Almajid, Fahad M., Batirel, Ayse, Kulzhanova, Sholpan, Konkayeva, Maiya, Smagulova, Zauresh, Pehlivanoglu, Filiz, de Saram, Sophia, Gulsun, Serda, Amer, Fatma, Balkan, Ilker Inanc, Tekin, Recep, Cascio, Antonio, Dauby, Nicolas, Sirmatel, Fatma, Tasbakan, Meltem, Erdem, Aysegul, Wegdan, Ahmed Ashraf, Aydin, Ozlem, Cesur, Salih, Deniz, Secil, Senbayrak, Seniha, Denk, Affan, Duzenli, Tolga, Siméon, Soline, Oncul, Ahsen, Ozseker, Burak, Yakar, Tolga, Ormeci, Necati
Published in European journal of clinical microbiology & infectious diseases (01.03.2020)
Published in European journal of clinical microbiology & infectious diseases (01.03.2020)
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Journal Article
The predictors of long-COVID in the cohort of Turkish Thoracic Society- TURCOVID multicenter registry: One year follow-up results
Argun Baris, Serap, Baydar Toprak, Oya, Duru Cetinkaya, Pelin, Fakili, Fusun, Kokturk, Nurdan, Kul, Seval, Kayalar, Ozgecan, Tutuncu, Yildiz, Azak, Emel, Kuluozturk, Mutlu, Yildiz, Pinar, Deniz, Pelin, Kilinc, Oguz, Basyigit, Ilknur, Boyaci, Hasim, Hanta, Ismail, Kose, Neslihan, Sagcan, Gulseren, Cuhadaroglu, Caglar, Okur, Hacer, Ozger, Hasan, Ergan, Begum, Hafizoglu, Mehtap, Sayiner, Abdullah, Temel, Esra, Ozturk, Onder, Ciftci, Tansu, Oguzulgen, Ipek, Oguz, Vildan, Bayraktar, Firat, Ataoglu, Ozlem, Ercelik, Merve, Gulhan, Pinar, Erdem, Aysegul, Tor, Muge, Itil, Oya, Bayram, Hasan
Published in Asian Pacific journal of tropical medicine (01.09.2022)
Published in Asian Pacific journal of tropical medicine (01.09.2022)
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Journal Article
3146 – THE ‘NON-ESSENTIAL’ AMINO ACID CYSTEINE IS REQUIRED TO PREVENT FERROPTOSIS IN ACUTE MYELOID LEUKEMIA
Oudejans, Lieve, Cunningham, Alan, Geugien, Marjan, Martins, Diego Antonio Pereira, Wierenga, Albertus, Erdem, Ayşegül, Sternadt, Dominique, Huls, Gerwin, Schuringa, Jan Jacob
Published in Experimental hematology (2023)
Published in Experimental hematology (2023)
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Journal Article
Metabolism-Related Features Identify the Combination Metformin Plus NAMPT Inhibitors As a Selective Treatment Strategy in Acute Myeloid Leukemia
Weinhaeuser, Isabel, Pereira-Martins, Diego, Sternadt, Dominique, Griessinger, Emmanuel F, Silveira, Douglas RA, Coelho-Silva, Juan L, Alves-Silva, Antonio Bruno, Erdem, Ayşegül, Duarte, Bruno Koza Lino, Quek, Lynn, Traina, Fabiola, Saad, Sara Teresinha Olalla, Hilberink, Jacobien R, Ammatuna, Emanuele, Rego, Eduardo Magalhães, Huls, Geert A., Lucena-Araujo, Antonio R, Schuringa, Jan Jacob
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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