An Integrated Process Analytical Technology (PAT) Approach to Monitoring the Effect of Supercooling on Lyophilization Product and Process Parameters of Model Monoclonal Antibody Formulations
Awotwe−Otoo, David, Agarabi, Cyrus, Khan, Mansoor A.
Published in Journal of pharmaceutical sciences (01.07.2014)
Published in Journal of pharmaceutical sciences (01.07.2014)
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Journal Article
Application of quality by design elements for the development and optimization of an analytical method for protamine sulfate
Awotwe-Otoo, David, Agarabi, Cyrus, Faustino, Patrick J., Habib, Muhammad J., Lee, Sau, Khan, Mansoor A., Shah, Rakhi B.
Published in Journal of pharmaceutical and biomedical analysis (25.03.2012)
Published in Journal of pharmaceutical and biomedical analysis (25.03.2012)
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Journal Article
Exploring the linkage between cell culture process parameters and downstream processing utilizing a plackett‐burman design for a model monoclonal antibody
Agarabi, Cyrus D., Chavez, Brittany K., Lute, Scott C., Read, Erik K., Rogstad, Sarah, Awotwe‐Otoo, David, Brown, Matthew R., Boyne, Michael T., Brorson, Kurt A.
Published in Biotechnology progress (01.01.2017)
Published in Biotechnology progress (01.01.2017)
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Journal Article
Root cause evaluation of particulates in the lyophilized indomethacin sodium trihydrate plug for parenteral administration
Siddiqui, Akhtar, Rahman, Ziyaur, Khan, Saeed R., Awotwe-Otoo, David, Khan, Mansoor A.
Published in International journal of pharmaceutics (01.10.2014)
Published in International journal of pharmaceutics (01.10.2014)
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Journal Article
Quality by design: Impact of formulation variables and their interactions on quality attributes of a lyophilized monoclonal antibody
Awotwe-Otoo, David, Agarabi, Cyrus, Wu, Geoffrey K., Casey, Elizabeth, Read, Erik, Lute, Scott, Brorson, Kurt A., Khan, Mansoor A., Shah, Rakhi B.
Published in International journal of pharmaceutics (15.11.2012)
Published in International journal of pharmaceutics (15.11.2012)
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Journal Article
Impact of controlled ice nucleation on process performance and quality attributes of a lyophilized monoclonal antibody
Awotwe-Otoo, David, Agarabi, Cyrus, Read, Erik K., Lute, Scott, Brorson, Kurt A., Khan, Mansoor A., Shah, Rakhi B.
Published in International journal of pharmaceutics (25.06.2013)
Published in International journal of pharmaceutics (25.06.2013)
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Journal Article
Product and process understanding to relate the effect of freezing method on glycation and aggregation of lyophilized monoclonal antibody formulations
Awotwe-Otoo, David, Agarabi, Cyrus, Read, Erik K., Lute, Scott, Brorson, Kurt A., Khan, Mansoor A.
Published in International journal of pharmaceutics (25.07.2015)
Published in International journal of pharmaceutics (25.07.2015)
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Journal Article
Application of Optical Coherence Tomography Freeze-Drying Microscopy for Designing Lyophilization Process and Its Impact on Process Efficiency and Product Quality
Korang-Yeboah, Maxwell, Srinivasan, Charudharshini, Siddiqui, Akhtar, Awotwe-Otoo, David, Cruz, Celia N., Muhammad, Ashraf
Published in AAPS PharmSciTech (2018)
Published in AAPS PharmSciTech (2018)
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Journal Article
Evaluation of Anticancer Drug-Loaded Nanoparticle Characteristics by Nondestructive Methodologies
Awotwe-Otoo, David, Zidan, Ahmed S., Rahman, Ziyaur, Habib, Muhammad J.
Published in AAPS PharmSciTech (01.06.2012)
Published in AAPS PharmSciTech (01.06.2012)
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Journal Article
Physicochemical Characterization of Complex Drug Substances: Evaluation of Structural Similarities and Differences of Protamine Sulfate from Various Sources
Awotwe-Otoo, David, Agarabi, Cyrus, Keire, David, Lee, Sau, Raw, Andre, Yu, Lawrence, Habib, Muhammad J., Khan, Mansoor A., Shah, Rakhi B.
Published in The AAPS journal (01.09.2012)
Published in The AAPS journal (01.09.2012)
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Journal Article