Mutation Status of the Residual ATM Allele Is an Important Determinant of the Cellular Response to Chemotherapy and Survival in Patients With Chronic Lymphocytic Leukemia Containing an 11q Deletion
Austen, Belinda, Skowronska, Anna, Baker, Claire, Powell, Judith E, Gardiner, Anne, Oscier, David, Majid, Aneela, Dyer, Martin, Siebert, Reiner, Taylor, A Malcolm, Moss, Paul A, Stankovic, Tatjana
Published in Journal of clinical oncology (01.12.2007)
Published in Journal of clinical oncology (01.12.2007)
Get full text
Journal Article
ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele
SKOWRONSKA, Anna, AUSTEN, Belinda, TAYLOR, Malcolm A, STANKOVIC, Tatjana, POWELL, Judith E, WESTON, Victoria, OSCIER, David G, DYER, Martin J. S, MATUTES, Estella, PRATT, Guy, FEGAN, Christopher, MOSS, Paul
Published in Haematologica (Roma) (01.01.2012)
Published in Haematologica (Roma) (01.01.2012)
Get full text
Journal Article
Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia
Dunwell, Thomas L., Dickinson, Rachel E., Stankovic, Tatjana, Dallol, Ashraf, Weston, Victoria, Austen, Belinda, Catchpoole, Daniel, Maher, Eamonn R., Latif, Farida
Published in Epigenetics (16.05.2009)
Published in Epigenetics (16.05.2009)
Get full text
Journal Article
Calreticulin mutations and their importance in splanchnic vein thrombosis
Sekhar, Mallika, Patch, David, Austen, Belinda, Howard, Joanne, Hart, Stephen
Published in British journal of haematology (01.07.2016)
Published in British journal of haematology (01.07.2016)
Get full text
Journal Article
Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers
Pepper, Chris, Lin, Thet Thet, Pratt, Guy, Hewamana, Saman, Brennan, Paul, Hiller, Louise, Hills, Robert, Ward, Rachel, Starczynski, Jane, Austen, Belinda, Hooper, Laura, Stankovic, Tatjana, Fegan, Chris
Published in Blood (01.11.2008)
Published in Blood (01.11.2008)
Get full text
Journal Article
Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL
Austen, Belinda, Powell, Judith E., Alvi, Azra, Edwards, Ian, Hooper, Laura, Starczynski, Jane, Taylor, A. Malcolm R., Fegan, Christopher, Moss, Paul, Stankovic, Tatjana
Published in Blood (01.11.2005)
Published in Blood (01.11.2005)
Get full text
Journal Article
The Target UK Study: Real-World Evidence of Molecular Response to Tyrosine Kinase Inhibitors Supports European Leukemianet 2013 Recommendations for the Management of Chronic Myeloid Leukaemia
Milojkovic, Dragana, Clark, Richard E., Byrne, Jennifer L, Huntly, Brian J.P, Raghavan, Manoj, Wandroo, Farooq A, Ali, Sahra, Austen, Belinda, Ryan, Jacqueline, Friedrich, Karsten, Cross, Nicholas C.P., Mead, Adam J
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
Get full text
Journal Article
A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival
Alvi, Azra J., Austen, Belinda, Weston, Victoria J., Fegan, Christopher, MacCallum, David, Gianella-Borradori, Athos, Lane, David P., Hubank, Mike, Powell, Judith E., Wei, Wenbin, Taylor, A. Malcolm R., Moss, Paul A.H., Stankovic, Tatjana
Published in Blood (01.06.2005)
Published in Blood (01.06.2005)
Get full text
Journal Article
South Asian chronic lymphocytic leukaemia patients have more rapid disease progression in comparison to White patients
Gunawardana, Chaminda, Austen, Belinda, Powell, Judith E., Fegan, Christopher, Wandroo, Farooq, Jacobs, Abe, Pratt, Guy, Moss, Paul
Published in British journal of haematology (01.08.2008)
Published in British journal of haematology (01.08.2008)
Get full text
Journal Article
Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses
Stankovic, Tatjana, Hubank, Mike, Cronin, Debbie, Stewart, Grant S., Fletcher, Danielle, Bignell, Colin R., Alvi, Azra J., Austen, Belinda, Weston, Victoria J., Fegan, Christopher, Byrd, Philip J., Moss, PaulA.H., Taylor, A. Malcolm R.
Published in Blood (01.01.2004)
Published in Blood (01.01.2004)
Get full text
Journal Article
Increased Frequency of Constitutional PathogenicATM Mutations in CLL Patients Compared to Control Individuals Suggests An Aetiological Role
Stankovic, Tatjana, Austen, Belinda, Pratt, Guy, Skowronska, Anna, Oscier, David, Dyer, Martin JS, Matutes, Estella, Taylor, Malcolm, Moss, Paul
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
Get full text
Journal Article
Pathogenic ATM mutations occur rarely in a subset of multiple myeloma patients
Austen, Belinda, Barone, Giancarlo, Reiman, Anne, Byrd, Philip J., Baker, Claire, Starczynski, Jane, Nobbs, Michael C., Murphy, Raymond P., Enright, Helen, Chaila, Elijah, Quinn, John, Stankovic, Tatjana, Pratt, Guy, Taylor, A. Malcolm R.
Published in British journal of haematology (01.09.2008)
Published in British journal of haematology (01.09.2008)
Get full text
Journal Article
Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-κB survival pathway signaling
Weston, Victoria J., Austen, Belinda, Wei, Wenbin, Marston, Eliot, Alvi, Azra, Lawson, Sarah, Darbyshire, Philip J., Griffiths, Mike, Hill, Frank, Mann, Jill R., Moss, Paul A.H., Taylor, A. Malcolm R., Stankovic, Tatjana
Published in Blood (01.09.2004)
Published in Blood (01.09.2004)
Get full text
Journal Article
The Novel PARP Inhibitor, AZD2281, Targets Apoptotic Resistant ATM Mutant CLL Tumours for Cellular Killing
Weston, Victoria, Baker, Claire, Austen, Belinda, Taylor, Malcolm, Moss, Paul, Stankovic, Tanja
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
Get full text
Journal Article
Chronic Lymphocytic Leukaemia Has a More Aggressive Phenotype in Asians Compared to Caucasians
Austen, Belinda, Gunawardana, Chaminda, Pratt, Guy, Wandroo, Farooq, Jacobs, Abe, Powell, Judith, Moss, Paul
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
Get full text
Journal Article
A Novel Functional Assay Using Etoposide Plus Nutlin 3, FISH and Mutational Analysis Detects Heterogeneity of ATM/p53 Pathway Alterations in CLL
Best, Giles, Gardiner, Anne, Ibbotson, Rachel, Majid, Aneela, Walewska, Renata, Austen, Belinda, Stankovic, Tanja, Dyer, Martin, Oscier, David Graham
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
Get full text
Journal Article
Stratification by DNA Damage-Induced Apoptotic and Transcriptional Responses Provides Insight into the Molecular Mechanisms Underlying Blast Clearance Rates in Paediatric B-Precursor ALL
Marston, Eliot, Weston, Victoria, Austen, Belinda, Wakelam, Michael, Lawson, Sarah, Darbyshire, Phil, Jesson, Jenny, Moss, Paul, Stankovic, Tatjana
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
Get full text
Journal Article
CLL Tumours with a Deletion of 11q Form Two Functional Subgroups Based on the Mutation Status of the Remaining ATM Allele
Austen, Belinda, Podinovskaia, Maria, Almond, Claire, Fews, Graham, Gardiner, Anne, Oscier, David, Moss, Paul, Stankovic, Tanja
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
Get full text
Journal Article