Dual Inhibition of Bcl-2 and Bcl-xL Strikingly Enhances PI3K Inhibition-Induced Apoptosis in Human Myeloid Leukemia Cells through a GSK3- and Bim-Dependent Mechanism
RAHMANI, Mohamed, MAYO AUST, Mandy, ATTKISSON, Elisa, WILLIAMS, David C, FERREIRA-GONZALEZ, Andrea, GRANT, Steven
Published in Cancer research (Chicago, Ill.) (15.02.2013)
Published in Cancer research (Chicago, Ill.) (15.02.2013)
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Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process
Rahmani, Mohamed, Aust, Mandy Mayo, Attkisson, Elisa, Williams, David C., Ferreira-Gonzalez, Andrea, Grant, Steven
Published in Blood (21.06.2012)
Published in Blood (21.06.2012)
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Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation
Rahmani, Mohamed, Aust, Mandy Mayo, Hawkins, Elisa, Parker, Rebecca E, Ross, Masey, Kmieciak, Maciej, Reshko, Leonid Borisovich, Rizzo, Kathryn A, Dumur, Catherine I, Ferreira-Gonzalez, Andrea, Grant, Steven
Published in Haematologica (Roma) (01.12.2015)
Published in Haematologica (Roma) (01.12.2015)
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PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo
Rahmani, Mohamed, Aust, Mandy Mayo, Benson, Elisa C, Wallace, LaShanale, Friedberg, Jonathan, Grant, Steven
Published in Clinical cancer research (15.09.2014)
Published in Clinical cancer research (15.09.2014)
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Co-Administration of the mTORC1/TORC2 Inhibitor INK128 and the Bcl-2/Bcl-Xl Antagonist ABT-737 Kills Human Myeloid Leukemia Cells through Mcl-1 Down-Regulation and AKT Inactivation
Rahmani, Mohamed, Aust, Mandy Mayo, Hawkins, Elisa, Parker, Rebecca E, Reshko, Leonid, Ross, Masey, Kmieciak, Maciej, Rizzo, Kathryn Ann, Dumur, Catherine I, Ferreira-Gonzalez, Andrea, Grant, Steven
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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