BRCA1 and BRCA2 carriers with breast, ovarian and prostate cancer demonstrate a different pattern of metastatic disease compared with non‐carriers: results from a rapid autopsy programme
Thorne, Heather, Devereux, Lisa, Li, Jason, Alsop, Kathryn, Christie, Liz, Geelen, Courtney T, Burdett, Nikki, Pishas, Kathleen I, Woodford, Noel, Leditschke, Jodie, Izzath, Mohamed H M A, Strachan, Kate, Young, Gregory, Jaravaza, Rufaro D, Madadin, Mohammed S, Archer, Melanie, Glengarry, Joanna, Iles, Linda, Rathnaweera, Ajith, Hampson, Clare, Almazrooei, Khamis, Burke, Michael, Bandara, Pradeep, Ranson, David, Saeedi, Essa, McNally, Orla, Mileshkin, Linda, Hamilton, Anne, Ananda, Sumitra, Au‐Yeung, George, Antill, Yoland, Sandhu, Shahneen, Savas, Peter, Francis, Prudence A, Luen, Stephen, Loi, Sherene, Jennens, Ross, Scott, Clare, Moodie, Kate, Cummings, Margaret, Reid, Andrew, Reed, Amy McCart, Bowtell, David, Lakhani, Sunil R, Fox, Stephen
Published in Histopathology (01.07.2023)
Published in Histopathology (01.07.2023)
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Journal Article
Uptake of oncology multidisciplinary meeting recommendations
Au-Yeung, George H, Aly, Ahmad, Bui, Andrew, Vermeltfoort, Carmel M, Davis, Ian D
Published in Medical journal of Australia (16.01.2012)
Published in Medical journal of Australia (16.01.2012)
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Journal Article
mRNA vaccines: a transformative technology with applications beyond COVID-19
Overmars, Isabella, Au-Yeung, George, Nolan, Terence M, Steer, Andrew C
Published in Medical journal of Australia (18.07.2022)
Published in Medical journal of Australia (18.07.2022)
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Journal Article
Selective Targeting of Cyclin E1-Amplified High-Grade Serous Ovarian Cancer by Cyclin-Dependent Kinase 2 and AKT Inhibition
Au-Yeung, George, Lang, Franziska, Azar, Walid J, Mitchell, Chris, Jarman, Kate E, Lackovic, Kurt, Aziz, Diar, Cullinane, Carleen, Pearson, Richard B, Mileshkin, Linda, Rischin, Danny, Karst, Alison M, Drapkin, Ronny, Etemadmoghadam, Dariush, Bowtell, David D L
Published in Clinical cancer research (01.04.2017)
Published in Clinical cancer research (01.04.2017)
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Journal Article
Synthetic lethality between CCNE1 amplification and loss of BRCA1
Etemadmoghadam, Dariush, Weir, Barbara A., Au-Yeung, George, Alsop, Kathryn, Mitchell, Gillian, George, Joshy, Davis, Sally, D'Andrea, Alan D., Simpson, Kaylene, Hahn, William C., Bowtell, David D. L.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
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Journal Article
Noncanonical IL6 Signaling-Mediated Activation of YAP Regulates Cell Migration and Invasion in Ovarian Clear Cell Cancer
Azar, Walid J, Christie, Elizabeth L, Mitchell, Chris, Liu, David S, Au-Yeung, George, Bowtell, David D L
Published in Cancer research (Chicago, Ill.) (15.11.2020)
Published in Cancer research (Chicago, Ill.) (15.11.2020)
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Journal Article
EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas
Etemadmoghadam, Dariush, Azar, Walid J, Lei, Ying, Moujaber, Tania, Garsed, Dale W, Kennedy, Catherine J, Fereday, Sian, Mitchell, Chris, Chiew, Yoke-Eng, Hendley, Joy, Sharma, Raghwa, Harnett, Paul R, Li, Jason, Christie, Elizabeth L, Patch, Ann-Marie, George, Joshy, Au-Yeung, George, Mir Arnau, Gisela, Holloway, Timothy P, Semple, Timothy, Pearson, John V, Waddell, Nicola, Grimmond, Sean M, Köbel, Martin, Rizos, Helen, Lomakin, Ivan B, Bowtell, David D L, deFazio, Anna
Published in Cancer research (Chicago, Ill.) (15.08.2017)
Published in Cancer research (Chicago, Ill.) (15.08.2017)
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Journal Article
Homologous recombination proficient subtypes of high-grade serous ovarian cancer: treatment options for a poor prognosis group
Stiegeler, Nadja, Garsed, Dale W., Au-Yeung, George, Bowtell, David D. L., Heinzelmann-Schwarz, Viola, Zwimpfer, Tibor A.
Published in Frontiers in oncology (04.06.2024)
Published in Frontiers in oncology (04.06.2024)
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Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune response on drug exposure
Spreafico, Anna, Couselo, Eva Muñoz, Irmisch, Anja, Bessa, Juliana, Au-Yeung, George, Bechter, Oliver, Svane, Inge Marie, Sanmamed, Miguel F, Gambardella, Valentina, McKean, Meredith, Callahan, Margaret, Dummer, Reinhard, Klein, Christian, Umaña, Pablo, Justies, Nicole, Heil, Florian, Fahrni, Linda, Opolka-Hoffmann, Eugenia, Waldhauer, Inja, Bleul, Conrad, Staack, Roland F, Karanikas, Vaios, Fowler, Stephen
Published in Frontiers in oncology (21.03.2024)
Published in Frontiers in oncology (21.03.2024)
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Journal Article
Imaging for assessment of cancer treatment response to immune checkpoint inhibitors can be complementary in identifying hypophysitis
Galligan, Anna, Iravani, Amir, Lasocki, Arian, Wallace, Roslyn, Weppler, Alison M, Sachithanandan, Nirupa, Chiang, Cherie, Colman, Peter G, Wentworth, John, Spain, Lavinia, Au-Yeung, George, Lee, Belinda, Kay, Thomas W H, Hicks, Rodney J, Sandhu, Shahneen, Krishnamurthy, Balasubramanian
Published in Frontiers in endocrinology (Lausanne) (29.11.2023)
Published in Frontiers in endocrinology (Lausanne) (29.11.2023)
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Journal Article
i-Move, a personalised exercise intervention for patients with advanced melanoma receiving immunotherapy: a randomised feasibility trial protocol
Hyatt, Amelia, Gough, Karla, Murnane, Andrew, Au-Yeung, George, Dawson, Tamara, Pearson, Elizabeth, Dhillon, Haryana, Sandhu, Shahneen, Williams, Narelle, Paton, Elizabeth, Billett, Alex, Traill, Anya, Andersen, Hayley, Beedle, Victoria, Milne, Donna
Published in BMJ open (28.02.2020)
Published in BMJ open (28.02.2020)
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Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation
Wang, Minyu, Zadeh, Soroor, Pizzolla, Angela, Thia, Kevin, Gyorki, David E, McArthur, Grant A, Scolyer, Richard A, Long, Georgina, Wilmott, James S, Andrews, Miles C, Au-Yeung, George, Weppler, Ali, Sandhu, Shahneen, Trapani, Joseph A, Davis, Melissa J, Neeson, Paul Joseph
Published in Journal for immunotherapy of cancer (01.04.2022)
Published in Journal for immunotherapy of cancer (01.04.2022)
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548 CD8+ tissue-resident memory T cells are tumour reactive and increase after immunotherapy in a case of metastatic mucosal melanoma
Pizzolla, Angela, Keam, Simon, Vergara, Ismael, Caramia, Franco, Wang, Minyu, Kocovski, Nikolce, Nguyen, ThuNgoc, Macdonald, Sean, Tantalo, Daniela, Petrone, Pasquale, Aw Yeang, Han Xian, Gyorki, David, Weppler, Alison, Au-Yeung, George, Sandhu, Shahneen, Perdicchio, Maurizio, McArthur, Grant, Papenfuss, Tony, Neeson, Paul
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Radiation with cisplatin or carboplatin for locally advanced cervix cancer: The experience of a tertiary cancer centre
Au-Yeung, George, Mileshkin, Linda, Bernshaw, David M, Kondalsamy-Chennakesavan, Srinivas, Rischin, Danny, Narayan, Kailash
Published in Journal of medical imaging and radiation oncology (01.02.2013)
Published in Journal of medical imaging and radiation oncology (01.02.2013)
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Journal Article
CCNE1 Amplification as a Therapeutic Target
Au-Yeung, George, Mileshkin, Linda, Bowtell, David D L
Published in Journal of clinical oncology (20.03.2023)
Published in Journal of clinical oncology (20.03.2023)
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Journal Article
Whole-genome characterization of chemoresistant ovarian cancer
Patch, Ann-Marie, Christie, Elizabeth L, Etemadmoghadam, Dariush, Garsed, Dale W, George, Joshy, Fereday, Sian, Nones, Katia, Cowin, Prue, Alsop, Kathryn, Bailey, Peter J, Kassahn, Karin S, Newell, Felicity, Quinn, Michael C J, Kazakoff, Stephen, Quek, Kelly, Wilhelm-Benartzi, Charlotte, Curry, Ed, Leong, Huei San, Hamilton, Anne, Mileshkin, Linda, Au-Yeung, George, Kennedy, Catherine, Hung, Jillian, Chiew, Yoke-Eng, Harnett, Paul, Friedlander, Michael, Quinn, Michael, Pyman, Jan, Cordner, Stephen, O'Brien, Patricia, Leditschke, Jodie, Young, Greg, Strachan, Kate, Waring, Paul, Azar, Walid, Mitchell, Chris, Traficante, Nadia, Hendley, Joy, Thorne, Heather, Shackleton, Mark, Miller, David K, Arnau, Gisela Mir, Tothill, Richard W, Holloway, Timothy P, Semple, Timothy, Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Idrisoglu, Senel, Bruxner, Timothy J C, Christ, Angelika N, Poudel, Barsha, Holmes, Oliver, Anderson, Matthew, Leonard, Conrad, Lonie, Andrew, Hall, Nathan, Wood, Scott, Taylor, Darrin F, Xu, Qinying, Fink, J Lynn, Waddell, Nick, Drapkin, Ronny, Stronach, Euan, Gabra, Hani, Brown, Robert, Jewell, Andrea, Nagaraj, Shivashankar H, Markham, Emma, Wilson, Peter J, Ellul, Jason, McNally, Orla, Doyle, Maria A, Vedururu, Ravikiran, Stewart, Collin, Lengyel, Ernst, Pearson, John V, Waddell, Nicola, deFazio, Anna, Grimmond, Sean M, Bowtell, David D L
Published in Nature (London) (28.05.2015)
Published in Nature (London) (28.05.2015)
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Journal Article
Abstract A48: Antiapoptotic gene expression and sensitivity to BH3-mimetics in chemoresistant, high-grade serous ovarian cancer cell lines
Mapagu, Cristina, Srirangan, Sivatharsny, Au-Yeung, George, Harnett, Paul R., Bowtell, David D., deFazio, Anna
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Abstract IA04: Drug resistance in end-stage high-grade serous ovarian cancer
Christie, Elizabeth L., Alsop, Kathryn, Au-Yeung, George, Pandey, Ahwan, Bowtell, David D.L.
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Journal Article
The molecular origin and taxonomy of mucinous ovarian carcinoma
Cheasley, Dane, Wakefield, Matthew J, Ryland, Georgina L, Allan, Prue E, Alsop, Kathryn, Amarasinghe, Kaushalya C, Ananda, Sumitra, Anglesio, Michael S, Au-Yeung, George, Böhm, Maret, Bowtell, David D L, Brand, Alison, Chenevix-Trench, Georgia, Christie, Michael, Chiew, Yoke-Eng, Churchman, Michael, DeFazio, Anna, Demeo, Renee, Dudley, Rhiannon, Fairweather, Nicole, Fedele, Clare G, Fereday, Sian, Fox, Stephen B, Gilks, C Blake, Gourley, Charlie, Hacker, Neville F, Hadley, Alison M, Hendley, Joy, Ho, Gwo-Yaw, Hughes, Siobhan, Hunstman, David G, Hunter, Sally M, Jobling, Tom W, Kalli, Kimberly R, Kaufmann, Scott H, Kennedy, Catherine J, Köbel, Martin, Le Page, Cecile, Li, Jason, Lupat, Richard, McNally, Orla M, McAlpine, Jessica N, Mes-Masson, Anne-Marie, Mileshkin, Linda, Provencher, Diane M, Pyman, Jan, Rahimi, Kurosh, Rowley, Simone M, Salazar, Carolina, Samimi, Goli, Saunders, Hugo, Semple, Timothy, Sharma, Ragwha, Sharpe, Alice J, Stephens, Andrew N, Thio, Niko, Torres, Michelle C, Traficante, Nadia, Xing, Zhongyue, Zethoven, Magnus, Antill, Yoland C, Scott, Clare L, Campbell, Ian G, Gorringe, Kylie L
Published in Nature communications (02.09.2019)
Published in Nature communications (02.09.2019)
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Journal Article
19q12 amplified and non-amplified subsets of high grade serous ovarian cancer with overexpression of cyclin E1 differ in their molecular drivers and clinical outcomes
Aziz, Diar, Etemadmoghadam, Dariush, Caldon, C. Elizabeth, Au-Yeung, George, Deng, Niantao, Hutchinson, Ryan, Bowtell, David, Waring, Paul
Published in Gynecologic oncology (01.11.2018)
Published in Gynecologic oncology (01.11.2018)
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