Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation
Abdelhameed, Ali S, Attwa, Mohamed W, Kadi, Adnan A
Published in Molecules (Basel, Switzerland) (28.10.2020)
Published in Molecules (Basel, Switzerland) (28.10.2020)
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Journal Article
Investigation of metabolic degradation of new ALK inhibitor: Entrectinib by LC-MS/MS
Attwa, Mohamed W., Darwish, Hany W., Alhazmi, Hassan A., Kadi, Adnan A.
Published in Clinica chimica acta (01.10.2018)
Published in Clinica chimica acta (01.10.2018)
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Journal Article
A Novel Green Micellar HPLC-UV Method for the Estimation of Vandetanib in Pure Form, Human Urine, Human Plasma and Human Liver Microsomes Matrices with Application to Metabolic Stability Evaluation
Alanazi, Mohammed M, Obaidullah, Ahmad J, Attwa, Mohamed W
Published in Molecules (Basel, Switzerland) (01.12.2022)
Published in Molecules (Basel, Switzerland) (01.12.2022)
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Journal Article
Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma
Attwa, Mohamed W, Kadi, Adnan A, Darwish, Hany W, Abdelhameed, Ali S
Published in RSC advances (01.01.2018)
Published in RSC advances (01.01.2018)
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Journal Article
Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation
Attwa, Mohamed W, AlRabiah, Haitham, Mostafa, Gamal A E, Kadi, Adnan A
Published in Molecules (Basel, Switzerland) (01.03.2023)
Published in Molecules (Basel, Switzerland) (01.03.2023)
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Journal Article
Selective Stability Indicating Liquid Chromatographic Method Based on Quality by Design Framework and In Silico Toxicity Assessment for Infigratinib and Its Degradation Products
Ali, Awadh M, Alanazi, Mohammed M, Attwa, Mohamed W, Darwish, Hany W
Published in Molecules (Basel, Switzerland) (01.11.2023)
Published in Molecules (Basel, Switzerland) (01.11.2023)
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Journal Article
A simple liquid chromatography-tandem mass spectrometry method to accurately determine the novel third-generation EGFR-TKI naquotinib with its applicability to metabolic stability assessment
Alrabiah, Haitham, Kadi, Adnan A, Attwa, Mohamed W, Abdelhameed, Ali S
Published in RSC advances (07.02.2019)
Published in RSC advances (07.02.2019)
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Journal Article
Editorial: Drug metabolism-induced organ toxicity
Kadi, Adnan A, Li, Yang, Parashar, Abhinav, Attwa, Mohamed W
Published in Frontiers in pharmacology (2024)
Published in Frontiers in pharmacology (2024)
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Journal Article
EGFR Inhibitor Gefitinib Induces Cardiotoxicity through the Modulation of Cardiac PTEN/Akt/FoxO3a Pathway and Reactive Metabolites Formation: In Vivo and in Vitro Rat Studies
Alhoshani, Ali, Alanazi, Fawaz E, Alotaibi, Moureq R, Attwa, Mohamed W, Kadi, Adnan A, Aldhfyan, Abdullah, Akhtar, Sabah, Hourani, Shireen, Agouni, Abdelali, Zeidan, Asad, Korashy, Hesham M
Published in Chemical research in toxicology (20.07.2020)
Published in Chemical research in toxicology (20.07.2020)
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Journal Article
A Validated LC-MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation
Attwa, Mohamed W, Darwish, Hany W, Al-Shakliah, Nasser S, Kadi, Adnan A
Published in Molecules (Basel, Switzerland) (05.05.2021)
Published in Molecules (Basel, Switzerland) (05.05.2021)
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Journal Article
Ionophore-Based Polymeric Sensors for Potentiometric Assay of the Anticancer Drug Gemcitabine in Pharmaceutical Formulation: A Comparative Study
Mostafa, Gamal A. E, El-Tohamy, Maha F, Ali, Essam A, Al-Salahi, Rashad, Attwa, Mohamed W, AlRabiah, Haitham
Published in Molecules (Basel, Switzerland) (01.11.2023)
Published in Molecules (Basel, Switzerland) (01.11.2023)
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Journal Article
Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles
Elzayat, Ehab M, Sherif, Abdelrahman Y, Nasr, Fahd A, Attwa, Mohamed W, Alshora, Doaa H, Ahmad, Sheikh F, Alqahtani, Ali S
Published in Materials (30.07.2023)
Published in Materials (30.07.2023)
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Journal Article
Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method
Attwa, Mohamed W, AlRabiah, Haitham, Mostafa, Gamal A E, Bakheit, Ahmed H, Kadi, Adnan A
Published in Molecules (Basel, Switzerland) (01.03.2023)
Published in Molecules (Basel, Switzerland) (01.03.2023)
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Journal Article