A Novel Model of Intravital Platelet Imaging Using CD41-ZsGreen1 Transgenic Rats
Mizuno, Makoto, Tomizawa, Atsuyuki, Ohno, Kousaku, Jakubowski, Joseph A, Sugidachi, Atsuhiro
Published in PloS one (29.04.2016)
Published in PloS one (29.04.2016)
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Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice
Ohno, Kousaku, Tomizawa, Atsuyuki, Jakubowski, Joseph A, Mizuno, Makoto, Sugidachi, Atsuhiro
Published in Thrombosis research (01.12.2015)
Published in Thrombosis research (01.12.2015)
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Comparison of antiplatelet effects of prasugrel and ticagrelor in cynomolgus monkeys by an ELISA-based VASP phosphorylation assay and platelet aggregation
Tomizawa, Atsuyuki, Ohno, Kousaku, Jakubowski, Joseph A, Mizuno, Makoto, Sugidachi, Atsuhiro
Published in Thrombosis and haemostasis (01.10.2013)
Published in Thrombosis and haemostasis (01.10.2013)
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Prasugrel, a Platelet P2Y12 Receptor Antagonist, Improves Abnormal Gait in a Novel Murine Model of Thrombotic Hindlimb Ischemia
Ohno, Kousaku, Tomizawa, Atsuyuki, Mizuno, Makoto, Jakubowski, Joseph A., Sugidachi, Atsuhiro
Published in Journal of the American Heart Association (06.04.2016)
Published in Journal of the American Heart Association (06.04.2016)
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Selective blockade of P2Y12 receptors by prasugrel inhibits myocardial infarction induced by thrombotic coronary artery occlusion in rats
Sugidachi, Atsuhiro, Yamaguchi, Shinji, Jakubowski, Joseph A, Ohno, Kosaku, Tomizawa, Atsuyuki, Hashimoto, Masami, Niitsu, Yoichi
Published in Journal of cardiovascular pharmacology (01.09.2011)
Published in Journal of cardiovascular pharmacology (01.09.2011)
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Pharmacological Profile of Novel Acid Pump Antagonist 7-(4-Fluorobenzyloxy)-2,3-dimethyl-1-{[(1S,2S)-2-methyl cyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526)
Keiichi Ito, Kazuya Kinoshita, Atsuyuki Tomizawa, Fumi Inaba, Yuka Morikawa-Inomata, Mitsuko Makino, Keiichi Tabata, Nobuhiko Shibakawa
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
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Pharmacodynamic and Pharmacokinetic Evaluation of CS-526 in Cynomolgus Monkeys
Ito, Keiichi, Kinoshita, Kazuya, Yamamura, Naotoshi, Tomizawa, Atsuyuki, Inaba, Fumi, Morikawa-Inomata, Yuka, Tabata, Keiichi, Shibakawa, Nobuhiko
Published in Biological & Pharmaceutical Bulletin (01.12.2009)
Published in Biological & Pharmaceutical Bulletin (01.12.2009)
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The Effect of Subchronic Administration of 7-(4-Fluorobenzyloxy)-2,3-dimethyl-1-{[(1S,2S)-2-methylcyclopropyl]methyl}-1H-pyrrolo[2,3-d]pyridazine (CS-526), a Novel Acid Pump Antagonist, on Gastric Acid Secretion and Gastrin Levels in Rats
Ito, Keiichi, Kinoshita, Kazuya, Tomizawa, Atsuyuki, Morikawa-Inomata, Yuka, Inaba, Fumi, Fujita, Yoshifumi, Tabata, Keiichi, Shibakawa, Nobuhiko
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
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The active metabolite of prasugrel, R-138727, improves cerebral blood flow and reduces cerebral infarction and neurologic deficits in a non-human primate model of acute ischaemic stroke
Sugidachi, Atsuhiro, Mizuno, Makoto, Ohno, Kousaku, Jakubowski, Joseph A., Tomizawa, Atsuyuki
Published in European journal of pharmacology (05.10.2016)
Published in European journal of pharmacology (05.10.2016)
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Vasodilator-stimulated phosphoprotein (VASP) is not a major mediator of platelet aggregation, thrombogenesis, haemostasis, and antiplatelet effect of prasugrel in rats
Ito, Yusuke, Ohno, Kousaku, Morikawa, Yuka, Tomizawa, Atsuyuki, Mizuno, Makoto, Sugidachi, Atsuhiro
Published in Scientific reports (02.07.2018)
Published in Scientific reports (02.07.2018)
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Prasugrel reduces ischaemic infarct volume and ameliorates neurological deficits in a non-human primate model of middle cerebral artery thrombosis
Tomizawa, Atsuyuki, Ohno, Kousaku, Jakubowski, Joseph A, Mizuno, Makoto, Sugidachi, Atsuhiro
Published in Thrombosis research (01.12.2015)
Published in Thrombosis research (01.12.2015)
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Abstract 321: Prasugrel, a Platelet P2y 12 Receptor Antagonist, Improves Abnormal Gait in a Novel Murine Model of Thrombotic Hind Limb Ischaemia
Ohno, Kousaku, Tomizawa, Atsuyuki, Mizuno, Makoto, Jakubowski, Joseph A, Sugidachi, Atsuhiro
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2016)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2016)
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Characterization of platelet aggregation responses in microminipigs: Comparison with miniature pigs and the influence of dual antiplatelet administration of aspirin plus prasugrel
Ohno, Kousaku, Tomizawa, Atsuyuki, Jakubowski, Joseph A, Mizuno, Makoto, Sugidachi, Atsuhiro
Published in Thrombosis research (01.05.2015)
Published in Thrombosis research (01.05.2015)
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Possible Role Of Circulating Adenine Nucleotides and Platelet Activation In The Pathogenesis Of Sickle Cell Disease: Observations In a Murine Model
Ohno, Kousaku, Tanaka, Hisako, Samata, Naozumi, Atsuyuki, Tomizawa, Mizuno, Makoto, Jakubowski, Joseph A., Sugidachi, Atsuhiro
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Prasugrel, a Platelet P2Y 12 Receptor Antagonist, Improves Abnormal Gait in a Novel Murine Model of Thrombotic Hindlimb Ischemia
Ohno, Kousaku, Tomizawa, Atsuyuki, Mizuno, Makoto, Jakubowski, Joseph A., Sugidachi, Atsuhiro
Published in Journal of the American Heart Association (03.04.2016)
Published in Journal of the American Heart Association (03.04.2016)
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Carbamoyl-PROXYL-enhanced MRI detects very small disruptions in brain vascular permeability induced by dietary cholesterol
Tomizawa, Atsuyuki, Ishii, Itsuko, Zhelev, Zhivko, Aoki, Ichio, Shibata, Sayaka, Kitada, Mitsukazu, Bakalova, Rumiana
Published in Biochimica et biophysica acta (01.12.2011)
Published in Biochimica et biophysica acta (01.12.2011)
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Nitroxide Derivatives for Imaging of Hypercholesterolemia-Induced Kidney Dysfunction and Assessing the Effectiveness of Antilipidemic Drugs
Tomizawa, Atsuyuki, Hadjidekov, George, Ishii, Itsuko, Bakalova, Rumiana, Zhelev, Zhivko, Aoki, Ichio, Saga, Tsuneo, Kitada, Mitsukazu
Published in Molecular pharmaceutics (03.10.2011)
Published in Molecular pharmaceutics (03.10.2011)
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