Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns
Moore, A S, Faisal, A, de Castro, D Gonzalez, Bavetsias, V, Sun, C, Atrash, B, Valenti, M, de Haven Brandon, A, Avery, S, Mair, D, Mirabella, F, Swansbury, J, Pearson, A D J, Workman, P, Blagg, J, Raynaud, F I, Eccles, S A, Linardopoulos, S
Published in Leukemia (01.07.2012)
Published in Leukemia (01.07.2012)
Get full text
Journal Article
Potent new inhibitors of human renin
Szelke, M, Leckie, B, Hallett, A, Jones, D M, Sueiras, J, Atrash, B, Lever, A F
Published in Nature (London) (07.10.1982)
Published in Nature (London) (07.10.1982)
Get more information
Journal Article
High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes
Foundling, S I, Cooper, J, Watson, F E, Cleasby, A, Pearl, L H, Sibanda, B L, Hemmings, A, Wood, S P, Blundell, T L, Valler, M J
Published in Nature (London) (28.05.1987)
Published in Nature (London) (28.05.1987)
Get more information
Journal Article
Selective FLT3 inhibition of [FLT3-ITD.sup.+] acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns
Moore, A.S, Faisal, A, de Castro, D. Gonzalez, Bavetsias, V, Sun, C, Atrash, B, Valenti, M, Brandon, A. de Haven, Avery, S, Mair, D, Mirabella, F, Swansbury, J, Pearson, A.D.J, Workman, P, Blagg, J, Raynaud, F.I, Eccles, S.A, Linardopoulos, S
Published in Leukemia (01.07.2012)
Published in Leukemia (01.07.2012)
Get full text
Journal Article
Selective FLT3 inhibition of FLT3-ITD super(+) acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns
Moore, A S, Faisal, A, de Castro, D Gonzalez, Bavetsias, V, Sun, C, Atrash, B, Valenti, M, de Haven Brandon, A, Avery, S, Mair, D, Mirabella, F, Swansbury, J, Pearson, A D J, Workman, P, Blagg, J, Raynaud, F I, Eccles, S A, Linardopoulos, S
Published in Leukemia (01.07.2012)
Published in Leukemia (01.07.2012)
Get full text
Journal Article
Synthesis of resorcinylic macrocycles related to radicicol via ring-closing metathesis
Cooper, Tracey S., Atrash, Butrus, Sheldrake, Peter, Workman, Paul, McDonald, Edward
Published in Tetrahedron letters (27.03.2006)
Published in Tetrahedron letters (27.03.2006)
Get full text
Journal Article
Revolutionizing Resin Handling for Combinatorial Synthesis
Atrash, Butrus, Bradley, Mark, Kobylecki, Ryzard, Cowell, Dan, Reader, John
Published in Angewandte Chemie International Edition (02.03.2001)
Published in Angewandte Chemie International Edition (02.03.2001)
Get full text
Journal Article
Development of synthetic routes to macrocyclic compounds based on the HSP90 inhibitor radicicol
Atrash, Butrus, Cooper, Tracey S., Sheldrake, Peter, Workman, Paul, McDonald, Edward
Published in Tetrahedron letters (27.03.2006)
Published in Tetrahedron letters (27.03.2006)
Get full text
Journal Article
Crystallographic studies of reduced bond inhibitors complexed with an aspartic proteinase
Foundling, S I, Cooper, J, Watson, F E, Pearl, L H, Hemmings, A, Wood, S P, Blundell, T, Hallett, A, Jones, D M, Sueiras, J
Published in Journal of cardiovascular pharmacology (1987)
Published in Journal of cardiovascular pharmacology (1987)
Get more information
Journal Article
Inhibitors of aspartic proteinases and their relevance to the design of antihypertensive agents
Cooper, J B, Foundling, S I, Hemmings, A, Watson, F E, Sibanda, B L, Blundell, T L, Jones, D M, Hallett, A, Atrash, B, Szelke, M
Published in Biochemical Society transactions (01.08.1987)
Published in Biochemical Society transactions (01.08.1987)
Get more information
Journal Article
Human renin inhibitors
Leckie, B J, Szelke, M, Atrash, B, Beattie, S R, Hallett, A, Jones, D M, McIntyre, G D, Suerias, J, Webb, D J
Published in Biochemical Society transactions (01.12.1985)
Published in Biochemical Society transactions (01.12.1985)
Get more information
Journal Article
Renin inhibitors: their use in understanding the role of angiotensin II as a pressor hormone
Tree, M, Szelke, M, Leckie, B, Atrash, B, Donovan, B, Hallett, A, Jones, D M, Lever, A F, Morton, J J, Sueiras-Diaz, J
Published in Journal of cardiovascular pharmacology (1985)
Published in Journal of cardiovascular pharmacology (1985)
Get more information
Journal Article
4-cyanothiazolidides as very potent, stable inhibitors of dipeptidyl peptidase IV
Ashworth, Doreen M., Atrash, Butrus, Baker, Graham R., Baxter, Andrew J., Jenkins, Paul D., Jones, D. Michael, Szelke, Michael
Published in Bioorganic & medicinal chemistry letters (19.11.1996)
Published in Bioorganic & medicinal chemistry letters (19.11.1996)
Get full text
Journal Article