Ticagrelor vs placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study
Heeney, Matthew M., Abboud, Miguel R., Githanga, Jessie, Inusa, Baba P.D., Kanter, Julie, Michelson, Alan D., Nduba, Videlis, Musiime, Victor, Apte, Mohini, Inati, Adlette, Taksande, Amar M., Andersson, Marielle, Åstrand, Magnus, Maklad, Noha, Niazi, Mohammad, Himmelmann, Anders, Berggren, Anders R.
Published in Blood (29.09.2022)
Published in Blood (29.09.2022)
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Journal Article
Novel Relaxin Receptor RXFP1 Agonist AZD3427 in the Treatment of Heart Failure: A Phase 1a/b, First-in-Human, Randomized, Single-Blind, Placebo-Controlled Study
Connolly, Kathleen, George, Richard, Omar, Sami, Matsson, Elin, Åstrand, Magnus, Althage, Magnus, Pettersen, Daniel, Mohamed, Esha, Fang, Kelly, Lima, Joao A C, Kujacic, Mirjana, Ödesjö, Helena, Turton, Michelle, Johannesson, Petra, Gabrielsen, Anders, Ufnal, Marcin
Published in Journal of the American Heart Association (06.08.2024)
Published in Journal of the American Heart Association (06.08.2024)
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Journal Article
Effect of Tenapanor on Serum Phosphate in Patients Receiving Hemodialysis
Block, Geoffrey A, Rosenbaum, David P, Leonsson-Zachrisson, Maria, Åstrand, Magnus, Johansson, Susanne, Knutsson, Mikael, Langkilde, Anna Maria, Chertow, Glenn M
Published in Journal of the American Society of Nephrology (01.06.2017)
Published in Journal of the American Society of Nephrology (01.06.2017)
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Population Pharmacokinetic Modeling of Cotadutide: A Dual Agonist Peptide of Glucagon-Like Peptide and Glucagon Receptors Administered to Participants with Type II Diabetes Mellitus, Chronic Kidney Disease, Obesity and Non-Alcoholic Steatohepatitis
Yu, Hongtao, Åstrand, Magnus, Cheng, Jenny, Nitin, Kaila, Hamrén, Bengt, Khan, Anis A.
Published in Clinical pharmacokinetics (01.02.2024)
Published in Clinical pharmacokinetics (01.02.2024)
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Zibotentan in combination with dapagliflozin compared with dapagliflozin in patients with chronic kidney disease (ZENITH-CKD): a multicentre, randomised, active-controlled, phase 2b, clinical trial
Heerspink, Hiddo J L, Kiyosue, Arihiro, Wheeler, David C, Lin, Min, Wijkmark, Emma, Carlson, Glenn, Mercier, Anne-Kristina, Åstrand, Magnus, Ueckert, Sebastian, Greasley, Peter J, Ambery, Phil
Published in The Lancet (British edition) (25.11.2023)
Published in The Lancet (British edition) (25.11.2023)
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Journal Article
From Plan to Pivot: How Model‐Informed Drug Development Shaped the Dose Strategy of the Zibotentan/Dapagliflozin ZENITH Trials
Mercier, Anne‐Kristina, Ueckert, Sebastian, Sunnåker, Mikael, Hamrén, Bengt, Ambery, Phil, Greasley, Peter J., Åstrand, Magnus
Published in Clinical pharmacology and therapeutics (01.09.2024)
Published in Clinical pharmacology and therapeutics (01.09.2024)
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Journal Article
Dose-Response Mixed Models for Repeated Measures – a New Method for Assessment of Dose-Response
Wellhagen, Gustaf J., Hamrén, Bengt, Kjellsson, Maria C., Åstrand, Magnus
Published in Pharmaceutical research (01.08.2020)
Published in Pharmaceutical research (01.08.2020)
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Journal Article
Population Pharmacokinetics/Pharmacodynamics of Ticagrelor in Children with Sickle Cell Disease
Amilon, Carl, Niazi, Mohammad, Berggren, Anders, Åstrand, Magnus, Hamrén, Bengt
Published in Clinical pharmacokinetics (01.10.2019)
Published in Clinical pharmacokinetics (01.10.2019)
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Journal Article
Pharmacokinetics of Roxadustat: A Population Analysis of 2855 Dialysis- and Non-Dialysis-Dependent Patients with Chronic Kidney Disease
Rekić, Dinko, Kerbusch-Herben, Virginie, Någård, Mats, Chou, James, Huang, Jiayin, Bradley, Charles, Åstrand, Magnus, Tannenbaum, Stacey, Hamrén, Bengt
Published in Clinical pharmacokinetics (01.06.2021)
Published in Clinical pharmacokinetics (01.06.2021)
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Journal Article
Population pharmacokinetic/target engagement modelling of tozorakimab in healthy volunteers and patients with chronic obstructive pulmonary disease
Sadiq, Muhammad Waqas, Yu, Hongtao, Åstrand, Magnus, Scott, Ian C, Williams, Adam, Hewitt, Lisa, White, Nicholas, Killick, Helen, Gavala, Monica, Cohen, E Suzanne, Reid, Fred, Kell, Chris, Pandya, Hitesh, Jimenez, Eulalia
Published in British journal of clinical pharmacology (25.08.2024)
Published in British journal of clinical pharmacology (25.08.2024)
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Effects of Zibotentan Alone and in Combination with Dapagliflozin on Fluid Retention in Patients with CKD
Smeijer, J David, Wasehuus, Victor S, Dhaun, Neeraj, Górriz, José Luis, Soler, Maria José, Åstrand, Magnus, Mercier, Anne-Kristina, Greasley, Peter J, Ambery, Phil, Heerspink, Hiddo J L
Published in Journal of the American Society of Nephrology (01.10.2024)
Published in Journal of the American Society of Nephrology (01.10.2024)
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Journal Article
Safety, Tolerability, and Pharmacodynamics of AZD3366 (Optimized Human CD39L3 Apyrase) Alone and in Combination With Ticagrelor and Acetylsalicylic Acid: A Phase 1, Randomized, Placebo-Controlled Study
Kardassis, Dimitris, Egnell, Ann-Charlotte, Åstrand, Magnus, Daniels, Samuel J, Whatling, Carl, Fjellström, Ola, Gabrielsen, Anders
Published in Journal of the American Heart Association (04.06.2024)
Published in Journal of the American Heart Association (04.06.2024)
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Journal Article
Pharmacokinetic–pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients
Åstrand, Magnus, Amilon, Carl, Röshammar, Daniel, Himmelmann, Anders, Angiolillo, Dominick J., Storey, Robert F., Gurbel, Paul A., Bonaca, Marc P., Hamrén, Bengt
Published in British journal of clinical pharmacology (01.02.2019)
Published in British journal of clinical pharmacology (01.02.2019)
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Journal Article
Model‐based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus
Parkinson, Joanna, Tang, Weifeng, Åstrand, Magnus, Melin, Johanna, Ekholm, Ella, Hamrén, Bengt, Boulton, David W.
Published in Diabetes, obesity & metabolism (01.06.2019)
Published in Diabetes, obesity & metabolism (01.06.2019)
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Journal Article
Pharmacokinetics and safety of ticagrelor in infants and toddlers with sickle cell disease aged <24 months
Duniva Inusa, Baba Psalm, Inati, Adlette, Maes, Philip, Githanga, Jessie, Ogutu, Bernhards, Abboud, Miguel R., Miano, Maurizio, Cela, Elena, Nduba, Videlis, Niazi, Mohammad, Åstrand, Magnus, Persson, Kevin, Berggren, Anders, Carlson, Glenn
Published in Pediatric blood & cancer (01.05.2021)
Published in Pediatric blood & cancer (01.05.2021)
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Journal Article
Activity of neutrophil elastase reflects the progression of acute pancreatitis
Novovic, Srdan, Andersen, Anders M., Nord, Magnus, Åstrand, Magnus, Ottosson, Tomas, Jørgensen, Lars N., Hansen, Mark B.
Published in Scandinavian journal of clinical and laboratory investigation (01.09.2013)
Published in Scandinavian journal of clinical and laboratory investigation (01.09.2013)
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Journal Article
Prevention of relapse of healed reflux esophagitis is related to the duration of intragastric pH > 4
Johnson, David A, Katz, Philip O, Levine, Doug, Röhss, Kerstin, Astrand, Magnus, Junghard, Ola, Nagy, Péter
Published in Journal of clinical gastroenterology (01.08.2010)
Published in Journal of clinical gastroenterology (01.08.2010)
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