BCKDK: an emerging kinase target for metabolic diseases and cancer
East, Michael P., Laitinen, Tuomo, Asquith, Christopher R. M.
Published in Nature reviews. Drug discovery (01.07.2021)
Published in Nature reviews. Drug discovery (01.07.2021)
Get full text
Journal Article
PIKfyve: a lipid kinase target for COVID-19, cancer and neurodegenerative disorders
Huang, Pei-Tzu, Einav, Shirit, Asquith, Christopher R. M.
Published in Nature reviews. Drug discovery (01.10.2021)
Published in Nature reviews. Drug discovery (01.10.2021)
Get full text
Journal Article
PKMYT1: a forgotten member of the WEE1 family
Asquith, Christopher R. M., Laitinen, Tuomo, East, Michael P.
Published in Nature reviews. Drug discovery (01.03.2020)
Published in Nature reviews. Drug discovery (01.03.2020)
Get full text
Journal Article
The Synthesis and Biological Applications of the 1,2,3-Dithiazole Scaffold
Kalogirou, Andreas S, Oh, Hans J, Asquith, Christopher R M
Published in Molecules (Basel, Switzerland) (01.04.2023)
Published in Molecules (Basel, Switzerland) (01.04.2023)
Get full text
Journal Article
PIP5K1A: a potential target for cancers with KRAS or TP53 mutations
East, Michael P., Laitinen, Tuomo, Asquith, Christopher R. M.
Published in Nature reviews. Drug discovery (01.07.2020)
Published in Nature reviews. Drug discovery (01.07.2020)
Get full text
Journal Article
WNK kinases: an untapped opportunity to modulate ion transport
East, Michael P., Laitinen, Tuomo, Asquith, Christopher R. M.
Published in Nature reviews. Drug discovery (01.12.2020)
Published in Nature reviews. Drug discovery (01.12.2020)
Get full text
Journal Article
Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma
Asquith, Christopher R. M, Naegeli, Kaleb M, East, Michael P, Laitinen, Tuomo, Havener, Tammy M, Wells, Carrow I, Johnson, Gary L, Drewry, David H, Zuercher, William J, Morris, David C
Published in Journal of medicinal chemistry (09.05.2019)
Published in Journal of medicinal chemistry (09.05.2019)
Get full text
Journal Article
SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK)
Asquith, Christopher R. M, Berger, Benedict-Tilman, Wan, Jing, Bennett, James M, Capuzzi, Stephen J, Crona, Daniel J, Drewry, David H, East, Michael P, Elkins, Jonathan M, Fedorov, Oleg, Godoi, Paulo H, Hunter, Debra M, Knapp, Stefan, Müller, Susanne, Torrice, Chad D, Wells, Carrow I, Earp, H. Shelton, Willson, Timothy M, Zuercher, William J
Published in Journal of medicinal chemistry (14.03.2019)
Published in Journal of medicinal chemistry (14.03.2019)
Get full text
Journal Article
Optimization of the 4-anilinoquin(az)oline scaffold as epidermal growth factor receptor (EGFR) inhibitors for chordoma utilizing a toxicology profiling assay platform
Bieberich, Andrew A., Laitinen, Tuomo, Maffuid, Kaitlyn, Fatig, Raymond O., Torrice, Chad D., Morris, David C., Crona, Daniel J., Asquith, Christopher R. M.
Published in Scientific reports (27.07.2022)
Published in Scientific reports (27.07.2022)
Get full text
Journal Article
Enhancing colistin efficacy against Salmonella infections with a quinazoline-based dual therapeutic strategy
Lobertti, Carlos A., Gizzi, Fernán O., Magni, Christian, Rial, Analía, Chabalgoity, José A., Yim, Lucía, Blancato, Víctor S., Asquith, Christopher R. M., García Véscovi, Eleonora
Published in Scientific reports (01.03.2024)
Published in Scientific reports (01.03.2024)
Get full text
Journal Article
Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data
Strang, Blair L, Asquith, Christopher R M, Moshrif, Hanan F, Ho, Catherine M-K, Zuercher, William J, Al-Ali, Hassan
Published in PloS one (26.07.2018)
Published in PloS one (26.07.2018)
Get full text
Journal Article
PKN3: a target in cancer metastasis
Temme, Louisa, Laitinen, Tuomo, Asquith, Christopher R. M.
Published in Nature reviews. Drug discovery (01.10.2022)
Published in Nature reviews. Drug discovery (01.10.2022)
Get full text
Journal Article
CDC42BPA/MRCKα: a kinase target for brain, ovarian and skin cancers
East, Michael P., Asquith, Christopher R. M.
Published in Nature reviews. Drug discovery (01.03.2021)
Published in Nature reviews. Drug discovery (01.03.2021)
Get full text
Journal Article
ADCK3/COQ8A: the choice target of the UbiB protein kinase-like family
Asquith, Christopher R. M., Murray, Nathan H., Pagliarini, David J.
Published in Nature reviews. Drug discovery (01.10.2019)
Published in Nature reviews. Drug discovery (01.10.2019)
Get full text
Journal Article
RIOK2: straddling the kinase/ATPase line
Asquith, Christopher R. M., East, Michael P., Zuercher, William J.
Published in Nature reviews. Drug discovery (01.07.2019)
Published in Nature reviews. Drug discovery (01.07.2019)
Get full text
Journal Article
Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System
Carabajal, María Ayelén, Asquith, Christopher R M, Laitinen, Tuomo, Tizzard, Graham J, Yim, Lucía, Rial, Analía, Chabalgoity, José A, Zuercher, William J, García Véscovi, Eleonora
Published in Antimicrobial agents and chemotherapy (20.12.2019)
Published in Antimicrobial agents and chemotherapy (20.12.2019)
Get full text
Journal Article
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification
Wells, Carrow I, Al-Ali, Hassan, Andrews, David M, Asquith, Christopher R M, Axtman, Alison D, Dikic, Ivan, Ebner, Daniel, Ettmayer, Peter, Fischer, Christian, Frederiksen, Mathias, Futrell, Robert E, Gray, Nathanael S, Hatch, Stephanie B, Knapp, Stefan, Lücking, Ulrich, Michaelides, Michael, Mills, Caitlin E, Müller, Susanne, Owen, Dafydd, Picado, Alfredo, Saikatendu, Kumar S, Schröder, Martin, Stolz, Alexandra, Tellechea, Mariana, Turunen, Brandon J, Vilar, Santiago, Wang, Jinhua, Zuercher, William J, Willson, Timothy M, Drewry, David H
Published in International journal of molecular sciences (08.01.2021)
Published in International journal of molecular sciences (08.01.2021)
Get full text
Journal Article