Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells
Angela, Mulki, Endo, Yusuke, Asou, Hikari K., Yamamoto, Takeshi, Tumes, Damon J., Tokuyama, Hirotake, Yokote, Koutaro, Nakayama, Toshinori
Published in Nature communications (30.11.2016)
Published in Nature communications (30.11.2016)
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The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway
Endo, Yusuke, Hirahara, Kiyoshi, Iinuma, Tomohisa, Shinoda, Kenta, Tumes, Damon J, Asou, Hikari K, Matsugae, Nao, Obata-Ninomiya, Kazushige, Yamamoto, Heizaburo, Motohashi, Shinichiro, Oboki, Keisuke, Nakae, Susumu, Saito, Hirohisa, Okamoto, Yoshitaka, Nakayama, Toshinori
Published in Immunity (Cambridge, Mass.) (17.02.2015)
Published in Immunity (Cambridge, Mass.) (17.02.2015)
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SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferon transcriptome in CD4+ T cells
Kanno, Toshio, Miyako, Keisuke, Nakajima, Takahiro, Yokoyama, Satoru, Sasamoto, Shigemi, Asou, Hikari K., Ohara, Osamu, Nakayama, Toshinori, Endo, Yusuke
Published in Frontiers in immunology (18.08.2022)
Published in Frontiers in immunology (18.08.2022)
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Journal Article
Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1
Endo, Yusuke, Asou, Hikari K., Matsugae, Nao, Hirahara, Kiyoshi, Shinoda, Kenta, Tumes, Damon J., Tokuyama, Hirotake, Yokote, Koutaro, Nakayama, Toshinori
Published in Cell reports (Cambridge) (11.08.2015)
Published in Cell reports (Cambridge) (11.08.2015)
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Journal Article
SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4+ T cells
Kanno, Toshio, Nakajima, Takahiro, Yokoyama, Satoru, Asou, Hikari K., Sasamoto, Shigemi, Kamii, Yasuhiro, Hayashizaki, Koji, Ouchi, Yasuo, Onodera, Taishi, Takahashi, Yoshimasa, Ikeda, Kazutaka, Hasegawa, Yoshinori, Kinjo, Yuki, Ohara, Osamu, Nakayama, Toshinori, Endo, Yusuke
Published in Communications biology (29.06.2021)
Published in Communications biology (29.06.2021)
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DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells
Yamamoto, Takeshi, Endo, Yusuke, Onodera, Atsushi, Hirahara, Kiyoshi, Asou, Hikari K., Nakajima, Takahiro, Kanno, Toshio, Ouchi, Yasuo, Uematsu, Satoshi, Nishimasu, Hiroshi, Nureki, Osamu, Tumes, Damon J., Shimojo, Naoki, Nakayama, Toshinori
Published in Nature communications (12.10.2018)
Published in Nature communications (12.10.2018)
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The integration of metabolic and proteomic data uncovers an augmentation of the sphingolipid biosynthesis pathway during T-cell differentiation
Kanno, Toshio, Konno, Ryo, Sato, Masaru, Kurabayashi, Atsushi, Miyako, Keisuke, Nakajima, Takahiro, Yokoyama, Satoru, Sasamoto, Shigemi, Asou, Hikari K., Ohzeki, Junichiro, Hasegawa, Yoshinori, Ikeda, Kazutaka, Kawashima, Yusuke, Ohara, Osamu, Endo, Yusuke
Published in Communications biology (23.05.2024)
Published in Communications biology (23.05.2024)
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ACC1-expressing pathogenic T helper 2 cell populations facilitate lung and skin inflammation in mice
Nakajima, Takahiro, Kanno, Toshio, Yokoyama, Satoru, Sasamoto, Shigemi, Asou, Hikari K, Tumes, Damon J, Ohara, Osamu, Nakayama, Toshinori, Endo, Yusuke
Published in The Journal of experimental medicine (06.12.2021)
Published in The Journal of experimental medicine (06.12.2021)
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Journal Article
Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue T reg cell homeostasis
Kanno, Toshio, Nakajima, Takahiro, Kawashima, Yusuke, Yokoyama, Satoru, Asou, Hikari K, Sasamoto, Shigemi, Hayashizaki, Koji, Kinjo, Yuki, Ohara, Osamu, Nakayama, Toshinori, Endo, Yusuke
Published in Cell reports (Cambridge) (09.11.2021)
Published in Cell reports (Cambridge) (09.11.2021)
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Journal Article
ACC1-mediated fatty acid biosynthesis intrinsically controls thymic iNKT cell development
Kanno, Toshio, Miyako, Keisuke, Endo, Takeru, Yokoyama, Satoru, Asou, Hikari K, Yamada, Kazuko, Ohara, Osamu, Nakayama, Toshinori, Kimura, Motoko Y, Endo, Yusuke
Published in International immunology (21.02.2024)
Published in International immunology (21.02.2024)
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Journal Article
Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
Kanno, Toshio, Nakajima, Takahiro, Kawashima, Yusuke, Yokoyama, Satoru, Asou, Hikari K., Sasamoto, Shigemi, Hayashizaki, Koji, Kinjo, Yuki, Ohara, Osamu, Nakayama, Toshinori, Endo, Yusuke
Published in Cell reports (Cambridge) (09.11.2021)
Published in Cell reports (Cambridge) (09.11.2021)
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Journal Article
Fatty acid metabolism constrains Th9 cell differentiation and antitumor immunity via the modulation of retinoic acid receptor signaling
Nakajima, Takahiro, Kanno, Toshio, Ueda, Yuki, Miyako, Keisuke, Endo, Takeru, Yoshida, Souta, Yokoyama, Satoru, Asou, Hikari K., Yamada, Kazuko, Ikeda, Kazutaka, Togashi, Yosuke, Endo, Yusuke
Published in Cellular & molecular immunology (26.08.2024)
Published in Cellular & molecular immunology (26.08.2024)
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Author Correction: Fatty acid metabolism constrains Th9 cell differentiation and antitumor immunity via the modulation of retinoic acid receptor signaling
Nakajima, Takahiro, Kanno, Toshio, Ueda, Yuki, Miyako, Keisuke, Endo, Takeru, Yoshida, Souta, Yokoyama, Satoru, Asou, Hikari K., Yamada, Kazuko, Ikeda, Kazutaka, Togashi, Yosuke, Endo, Yusuke
Published in Cellular & molecular immunology (08.10.2024)
Published in Cellular & molecular immunology (08.10.2024)
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Journal Article
Characterization of proteogenomic signatures of differentiation of CD4+ T cell subsets
Kanno, Toshio, Konno, Ryo, Miyako, Keisuke, Nakajima, Takahiro, Yokoyama, Satoru, Sasamoto, Shigemi, Asou, Hikari K, Ohzeki, Junichiro, Kawashima, Yusuke, Hasegawa, Yoshinori, Ohara, Osamu, Endo, Yusuke
Published in DNA research (01.02.2023)
Published in DNA research (01.02.2023)
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Journal Article
ACC1 determines memory potential of individual CD4 + T cells by regulating de novo fatty acid biosynthesis
Endo, Yusuke, Onodera, Atsushi, Obata-Ninomiya, Kazushige, Koyama-Nasu, Ryo, Asou, Hikari K, Ito, Toshihiro, Yamamoto, Takeshi, Kanno, Toshio, Nakajima, Takahiro, Ishiwata, Kenji, Kanuka, Hirotaka, Tumes, Damon J, Nakayama, Toshinori
Published in Nature metabolism (01.02.2019)
Published in Nature metabolism (01.02.2019)
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1-Oleoyl-lysophosphatidylethanolamine stimulates RORγt activity in T H 17 cells
Endo, Yusuke, Kanno, Toshio, Nakajima, Takahiro, Ikeda, Kazutaka, Taketomi, Yoshitaka, Yokoyama, Satoru, Sasamoto, Shigemi, Asou, Hikari K, Miyako, Keisuke, Hasegawa, Yoshinori, Kawashima, Yusuke, Ohara, Osamu, Murakami, Makoto, Nakayama, Toshinori
Published in Science immunology (04.08.2023)
Published in Science immunology (04.08.2023)
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Journal Article
DUSP10 constrains innate IL-33-mediated cytokine production in ST2 hi memory-type pathogenic Th2 cells
Yamamoto, Takeshi, Endo, Yusuke, Onodera, Atsushi, Hirahara, Kiyoshi, Asou, Hikari K, Nakajima, Takahiro, Kanno, Toshio, Ouchi, Yasuo, Uematsu, Satoshi, Nishimasu, Hiroshi, Nureki, Osamu, Tumes, Damon J, Shimojo, Naoki, Nakayama, Toshinori
Published in Nature communications (12.10.2018)
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Published in Nature communications (12.10.2018)
Journal Article
Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPAR[gamma] directs early activation of T cells
Angela, Mulki, Endo, Yusuke, Asou, Hikari K, Yamamoto, Takeshi, Tumes, Damon J, Tokuyama, Hirotake, Yokote, Koutaro, Nakayama, Toshinori
Published in Nature communications (01.11.2016)
Published in Nature communications (01.11.2016)
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