JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa
Boor, Patrick P.C., de Ruiter, Petra E., Asmawidjaja, Patrick S., Lubberts, Erik, van der Laan, Luc J.W., Kwekkeboom, Jaap
Published in Translational research : the journal of laboratory and clinical medicine (01.10.2017)
Published in Translational research : the journal of laboratory and clinical medicine (01.10.2017)
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Journal Article
Synovial fibroblasts directly induce Th17 pathogenicity via the cyclooxygenase/prostaglandin E2 pathway, independent of IL-23
Paulissen, Sandra M J, van Hamburg, Jan Piet, Davelaar, Nadine, Asmawidjaja, Patrick S, Hazes, Johanna M W, Lubberts, Erik
Published in The Journal of immunology (1950) (01.08.2013)
Published in The Journal of immunology (1950) (01.08.2013)
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Journal Article
IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation
Razawy, Wida, Alves, Celso H., Koedam, Marijke, Asmawidjaja, Patrick S., Mus, Adriana M. C., Oukka, Mohamed, Leenen, Pieter J. M., Visser, Jenny A., van der Eerden, Bram C. J., Lubberts, Erik
Published in Scientific reports (13.05.2021)
Published in Scientific reports (13.05.2021)
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Journal Article
Lack of IL-17 Receptor A signaling aggravates lymphoproliferation in C57BL/6 lpr mice
Corneth, Odilia B. J., Schaper, Fleur, Luk, Franka, Asmawidjaja, Patrick S., Mus, Adriana M. C., Horst, Gerda, Heeringa, Peter, Hendriks, Rudi W., Westra, Johanna, Lubberts, Erik
Published in Scientific reports (11.03.2019)
Published in Scientific reports (11.03.2019)
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Journal Article
Loss of IL‐22 inhibits autoantibody formation in collagen‐induced arthritis in mice
Corneth, Odilia B. J., Reijmers, Rogier M., Mus, Adriana M.C., Asmawidjaja, Patrick S., Hamburg, Jan Piet, Papazian, Natalie, Siegers, Jurre Y., Mourcin, Frédéric, Amin, Rada, Tarte, Karin, Hendriks, Rudi W., Cupedo, Tom, Lubberts, Erik
Published in European journal of immunology (01.06.2016)
Published in European journal of immunology (01.06.2016)
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Journal Article
IL-23 dependent and independent stages of experimental arthritis: no clinical effect of therapeutic IL-23p19 inhibition in collagen-induced arthritis
Cornelissen, Ferry, Asmawidjaja, Patrick S, Mus, Adriana M C, Corneth, Odilia, Kikly, Kristine, Lubberts, Erik
Published in PloS one (28.02.2013)
Published in PloS one (28.02.2013)
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Journal Article
1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade
Dankers, Wendy, González-Leal, Claudia, Davelaar, Nadine, Asmawidjaja, Patrick S., Mus, Adriana M. C., Hazes, Johanna M. W., Colin, Edgar M., Lubberts, Erik
Published in Arthritis research & therapy (20.09.2018)
Published in Arthritis research & therapy (20.09.2018)
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Journal Article
Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis
Alves, C Henrique, Ober-Blöbaum, Julia L, Brouwers-Haspels, Inge, Asmawidjaja, Patrick S, Mus, Adriana M C, Razawy, Wida, Molendijk, Marlieke, Clausen, Björn E, Lubberts, Erik
Published in PloS one (20.11.2015)
Published in PloS one (20.11.2015)
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Journal Article
Interleukin‐17A Is Produced by CD4+ but Not CD8+ T Cells in Synovial Fluid Following T Cell Receptor Activation and Regulates Different Inflammatory Mediators Compared to Tumor Necrosis Factor in a Model of Psoriatic Arthritis Synovitis
Xu, Xiaofei, Davelaar, Nadine, Mus, Anne‐Marie, Asmawidjaja, Patrick S., Hazes, Johanna M. W., Baeten, Dominique L. P., Vis, Marijn, Bisoendial, Radjesh J., Prens, Errol P., Lubberts, Erik
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2020)
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Journal Article
1,25(OH) 2 D 3 and dexamethasone additively suppress synovial fibroblast activation by CCR6 + T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade
Dankers, Wendy, González-Leal, Claudia, Davelaar, Nadine, Asmawidjaja, Patrick S, Mus, Adriana M C, Hazes, Johanna M W, Colin, Edgar M, Lubberts, Erik
Published in Arthritis research & therapy (20.09.2018)
Published in Arthritis research & therapy (20.09.2018)
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Journal Article
Enhanced Expression of Bruton's Tyrosine Kinase in B Cells Drives Systemic Autoimmunity by Disrupting T Cell Homeostasis
Corneth, Odilia B J, de Bruijn, Marjolein J W, Rip, Jasper, Asmawidjaja, Patrick S, Kil, Laurens P, Hendriks, Rudi W
Published in The Journal of immunology (1950) (01.07.2016)
Published in The Journal of immunology (1950) (01.07.2016)
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Journal Article
Allogeneic Chondrogenic Mesenchymal Stromal Cells Alter Helper T Cell Subsets in CD4+ Memory T Cells
Kiernan, Caoimhe H, Asmawidjaja, Patrick S, Fahy, Niamh, Witte-Bouma, Janneke, Wolvius, Eppo B, Brama, Pieter A J, Lubberts, Erik, Farrell, Eric, Physiol, Mod
Published in Tissue engineering. Part A (01.05.2020)
Published in Tissue engineering. Part A (01.05.2020)
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Journal Article
CD4+CCR6+ T cells, but not γδ T cells, are important for the IL‐23R‐dependent progression of antigen‐induced inflammatory arthritis in mice
Razawy, Wida, Asmawidjaja, Patrick S., Mus, Anne‐Marie, Salioska, Nazike, Davelaar, Nadine, Kops, Nicole, Oukka, Mohamed, Alves, C. Henrique, Lubberts, Erik
Published in European journal of immunology (01.02.2020)
Published in European journal of immunology (01.02.2020)
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Journal Article
Absence of Interleukin‐17 Receptor A Signaling Prevents Autoimmune Inflammation of the Joint and Leads to a Th2‐like Phenotype in Collagen‐Induced Arthritis
Corneth, Odilia B. J., Mus, Adriana M. C., Asmawidjaja, Patrick S., Klein Wolterink, Roel G. J., Nimwegen, Menno, Brem, Maarten D., Hofman, Yara, Hendriks, Rudi W., Lubberts, Erik
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2014)
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Journal Article
Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORγt in γδ T cells
Cornelissen, Ferry, Mus, Adriana MC, Asmawidjaja, Patrick S, van Hamburg, Jan Piet, Tocker, Joel, Lubberts, Erik
Published in Arthritis research & therapy (17.12.2009)
Published in Arthritis research & therapy (17.12.2009)
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Journal Article
A human vitamin D receptor mutation causes rickets and impaired Th1/Th17 responses
van der Eerden, Bram C.J, van der Heyden, Josine C, van Hamburg, Jan Piet, Schreuders-Koedam, Marijke, Asmawidjaja, Patrick S, de Muinck Keizer-Schrama, Sabine M, Boot, Annemieke M, Lubberts, Erik, Drop, Stenvert L.S, van Leeuwen, Johannes P.T.M
Published in Bone (New York, N.Y.) (01.12.2014)
Published in Bone (New York, N.Y.) (01.12.2014)
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Journal Article
Surrogate light chain expression beyond the pre-B cell stage promotes tolerance in a dose-dependent fashion
Kil, Laurens P, Corneth, Odilia B.J, de Bruijn, Marjolein J.W, Asmawidjaja, Patrick S, Krause, Arndt, Lubberts, Erik, van Loo, Pieter Fokko, Hendriks, Rudi W
Published in Journal of autoimmunity (01.02.2015)
Published in Journal of autoimmunity (01.02.2015)
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Journal Article
02.20 Regulation of interleukin 17 receptor d (il17rd) in synovial fibroblasts from rheumatoid arthritis patients and its function in collagen induced arthritis
Molendijk, Marlieke, Mus, Adriana MC, Asmawidjaja, Patrick S, Lubberts, Erik
Published in Annals of the rheumatic diseases (01.03.2017)
Published in Annals of the rheumatic diseases (01.03.2017)
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Journal Article