Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages
Gonzalez, Michael A, Lu, Daniel R, Yousefi, Maryam, Kroll, Ashley, Lo, Chen Hao, Briseño, Carlos G, Watson, J E Vivienne, Novitskiy, Sergey, Arias, Vanessa, Zhou, Hong, Plata Stapper, Andres, Tsai, Min K, Ashkin, Emily L, Murray, Christopher W, Li, Chi-Ming, Winslow, Monte M, Tarbell, Kristin V
Published in The Journal of experimental medicine (05.06.2023)
Published in The Journal of experimental medicine (05.06.2023)
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Journal Article
A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer
Cai, Hongchen, Chew, Su Kit, Li, Chuan, Tsai, Min K, Andrejka, Laura, Murray, Christopher W, Hughes, Nicholas W, Shuldiner, Emily G, Ashkin, Emily L, Tang, Rui, Hung, King L, Chen, Leo C, Lee, Shi Ya C, Yousefi, Maryam, Lin, Wen-Yang, Kunder, Christian A, Cong, Le, McFarland, Christopher D, Petrov, Dmitri A, Swanton, Charles, Winslow, Monte M
Published in Cancer discovery (01.07.2021)
Published in Cancer discovery (01.07.2021)
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Journal Article
Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Yousefi, Maryam, Boross, Gábor, Weiss, Carly, Murray, Christopher W, Hebert, Jess D, Cai, Hongchen, Ashkin, Emily L, Karmakar, Saswati, Andrejka, Laura, Chen, Leo, Wang, Minwei, Tsai, Min K, Lin, Wen-Yang, Li, Chuan, Yakhchalian, Pegah, Colón, Caterina I, Chew, Su-Kit, Chu, Pauline, Swanton, Charles, Kunder, Christian A, Petrov, Dmitri A, Winslow, Monte M
Published in Cancer research (Chicago, Ill.) (15.04.2022)
Published in Cancer research (Chicago, Ill.) (15.04.2022)
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Journal Article
Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity
Punt, Simone, Malu, Shruti, McKenzie, Jodi A., Manrique, Soraya Zorro, Doorduijn, Elien M., Mbofung, Rina M., Williams, Leila, Silverman, Deborah A., Ashkin, Emily L., Dominguez, Ana Lucía, Wang, Zhe, Chen, Jie Qing, Maiti, Sourindra N., Tieu, Trang N., Liu, Chengwen, Xu, Chunyu, Forget, Marie-Andrée, Haymaker, Cara, Khalili, Jahan S., Satani, Nikunj, Muller, Florian, Cooper, Laurence J. N., Overwijk, Willem W., Amaria, Rodabe N., Bernatchez, Chantale, Heffernan, Timothy P., Peng, Weiyi, Roszik, Jason, Hwu, Patrick
Published in Cancer Immunology, Immunotherapy (01.04.2021)
Published in Cancer Immunology, Immunotherapy (01.04.2021)
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A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis
Ashkin, Emily L, Tang, Yuning J, Xu, Haiqing, Hung, King L, Belk, Julia, Cai, Hongchen, Lopez, Steven, Dolcen, Deniz Nesli, Hebert, Jess D, Li, Rui, Ruiz, Paloma A, Keal, Tula, Andrejka, Laura, Chang, Howard Y, Petrov, Dmitri A, Dixon, Jesse R, Xu, Zhichao, Winslow, Monte M
Published in bioRxiv (19.09.2024)
Published in bioRxiv (19.09.2024)
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Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
Tang, Yuning J, Xu, Haiqing, Hughes, Nicholas W, Kim, Samuel H, Ruiz, Paloma, Shuldiner, Emily G, Lopez, Steven S, Hebert, Jess D, Karmakar, Saswati, Andrejka, Laura, Dolcen, D Nesli, Boross, Gabor, Chu, Pauline, Detrick, Colin, Pierce, Sarah, Ashkin, Emily L, Greenleaf, William J, Voss, Anne K, Thomas, Tim, van de Rijn, Matt, Petrov, Dmitri A, Winslow, Monte M
Published in bioRxiv (20.08.2024)
Published in bioRxiv (20.08.2024)
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Abstract 3956: A novel compound screen for enhancing T-cell based immunotherapy identifies aurora kinases as a targetable mechanism for tumor immune escape in pancreatic ductal adenocarcinoma preclinical models
Ashkin, Emily L., Silverman, Deborah, Punt, Simone, Manrique, Soraya Zorro, Williams, Leila, Wang, Yunfei, Hwu, Patrick
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract PO-076: Adrenergic regulation of the anti-tumor immune response in p53 -deficient tumors
Silverman, Deborah A., Akhter, Shamima, Xie, Tongxin, Islam, Shajedul, Anfossi, Simone, Covello, Jennifer D., Gleber-Netto, Frederico O., Doorduijn, Elien, Wang, Yunfei, Ashkin, Emily L., Myers, Jeffrey N., Calin, George A., Hwu, Patrick, Amit, Moran
Published in Clinical cancer research (15.09.2023)
Published in Clinical cancer research (15.09.2023)
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Abstract 821: Dissecting the role of Stag2 in lung adenocarcinoma
Ashkin, Emily L., Cai, Hongchen, Tang, Yuning J., Li, Chuan, Chew, Su Kit, Hung, King, Belk, Julia, Karmakar, Saswati, Hebert, Jess, Yousefi, Maryam, Swanton, Charles, Petrov, Dmitri A., Winslow, Monte
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 827: A journey to deconvolute the multifaceted functions and context-dependency of cancer driver genes
Cai, Hongchen, Chew, Su Kit, Li, Chuan, Murray, Christopher W., Andrejka, Laura, Hebert, Jess D., Tsai, Min K., Tang, Rui, Hughes, Nicholas W., Shuldiner, Emily G., Ashkin, Emily L., Lee, Shi Ya C., Yousefi, Maryam, Petrov, Dmitri A., Swanton, Charles, Winslow, Monte W.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities
Yousefi, Maryam, Boross, Gábor, Weiss, Carly, Murray, Christopher W, Hebert, Jess D, Cai, Hongchen, Ashkin, Emily L, Karmakar, Saswati, Andrejka, Laura, Chen, Leo, Wang, Minwei, Tsai, Min K, Wen-Yang, Lin, Li, Chuan, Yakhchalian, Pegah, Colón, Caterina I, Su-Kit Chew, Chu, Pauline, Swanton, Charles, Kunder, Christian A, Petrov, Dmitri A, Winslow, Monte M
Published in bioRxiv (14.12.2021)
Published in bioRxiv (14.12.2021)
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