Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype
Asemota, Sarah, Effah, Wendy, Young, Kirsten L., Holt, Jeremiah, Cripe, Linnea, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Hwang, Dong-Jin, He, Yali, Mcnamara, Keely, Johnson, Daniel, Wang, Yinan, Grimes, Brandy, Khosrosereshki, Yekta, Hollingsworth, T.J., Fleming, Martin D., Pritchard, Frances E., Hendrix, Ashley, Khan, Farhan, Fan, Meiyun, Makowski, Liza, Yin, Zheng, Sasano, Hironobu, Hayes, D. Neil, Pfeffer, Lawrence M., Miller, Duane D., Narayanan, Ramesh
Published in Cell reports (Cambridge) (26.12.2023)
Published in Cell reports (Cambridge) (26.12.2023)
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Journal Article
Androgen Receptor Is a Non-canonical Inhibitor of Wild-Type and Mutant Estrogen Receptors in Hormone Receptor-Positive Breast Cancers
Ponnusamy, Suriyan, Asemota, Sarah, Schwartzberg, Lee S., Guestini, Fouzia, McNamara, Keely M., Pierobon, Mariaelena, Font-Tello, Alba, Qiu, Xintao, Xie, Yingtian, Rao, Prakash K., Thiyagarajan, Thirumagal, Grimes, Brandy, Johnson, Daniel L., Fleming, Martin D., Pritchard, Frances E., Berry, Michael P., Oswaks, Roy, Fine, Richard E., Brown, Myles, Sasano, Hironobu, Petricoin, Emanuel F., Long, Henry W., Narayanan, Ramesh
Published in iScience (22.11.2019)
Published in iScience (22.11.2019)
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Journal Article
Integrin-Linked Kinase Is a Novel Therapeutic Target in Ovarian Cancer
Ulm, Michael A., Redfern, Tiffany M., Wilson, Ben R., Ponnusamy, Suriyan, Asemota, Sarah, Blackburn, Patrick W., Wang, Yinan, ElNaggar, Adam C., Narayanan, Ramesh
Published in Journal of personalized medicine (26.11.2020)
Published in Journal of personalized medicine (26.11.2020)
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Journal Article
Reciprocal interplay between OTULIN-LUBAC determines genotoxic and inflammatory NF-κB signal responses
Li, Mingqi, Li, Ling, Asemota, Sarah, Kakhniashvili, David, Narayanan, Ramesh, Wang, Xusheng, Liao, Francesca-Fang
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2022)
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Journal Article
Discovery of first-in-class mitogen activated protein kinase (MAPK) 8–10 activator for the treatment of high grade serous ovarian cancer (1287)
Masri, Amal, Wilson, Benjamin, Blackburn, Patrick, Martin, Alexandra, Asemota, Sarah, Hwang, Dong-Jin, Miller, Duane, Narayanan, Ramesh
Published in Gynecologic oncology (01.09.2023)
Published in Gynecologic oncology (01.09.2023)
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Journal Article
Abstract 6281: Context dependent role of glucocorticoids in breast cancer
Effah, Wendy, Ponnusamy, Suriyan, Asemota, Sarah, Khosrosereski, Yekta, Narayanan, Ramesh
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 5044: Integrin-linked kinase gene knockdown results in decreased growth of ovarian cancer xenograft models
Redfern, Tiffany, Wilson, Benjamin, Ulm, Michael, ElNaggar, Adam, Ponnusamy, Suriyan, Wang, Yinan, Asemota, Sarah, Narayanan, Ramesh
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Highly selective activator of Jun N-terminal kinase (JNK) for treatment of endometrioid ovarian carcinoma (1272)
Martin, Alexandra, Wilson, Benjamin, Blackburn, Patrick, Masri, Amal, Asemota, Sarah, Effah, Wendy, Ponnusamy, Thamarai, Thiyagarajan, Thirumagal, Hwang, Dong-Jin, Miller, Duane, Narayanan, Ramesh
Published in Gynecologic oncology (01.09.2023)
Published in Gynecologic oncology (01.09.2023)
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Journal Article
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer
Thiyagarajan, Thirumagal, Ponnusamy, Suriyan, Hwang, Dong-Jin, He, Yali, Asemota, Sarah, Young, Kirsten L, Johnson, Daniel L, Bocharova, Vera, Zhou, Weidong, Jain, Abhinav K, Petricoin, Emanuel F, Yin, Zheng, Pfeffer, Lawrence M, Miller, Duane D, Narayanan, Ramesh
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2023)
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Journal Article
Abstract 1235: Selective androgen receptor degraders for the treatment of androgen receptor-positive, triple-negative breast cancer
Asemota, Sarah, Young, Kirsten Young, Ponnusamy, Suriyan, Thiyagarajan, Thirumagal, Hwang, Dong-Jin, He, Yali, Breitmeyer, James B., Kaufmann, Gunnar F., Miller, Duane D., Narayanan, Ramesh
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
Pingili, Ajeeth K., Chaib, Mehdi, Sipe, Laura M., Miller, Emily J., Teng, Bin, Sharma, Rahul, Yarbro, Johnathan R., Asemota, Sarah, Al Abdallah, Qusai, Mims, Tahliyah S., Marion, Tony N., Daria, Deidre, Sekhri, Radhika, Hamilton, Alina M., Troester, Melissa A., Jo, Heejoon, Choi, Hyo Young, Hayes, D. Neil, Cook, Katherine L., Narayanan, Ramesh, Pierre, Joseph F., Makowski, Liza
Published in Cell reports (Cambridge) (22.06.2021)
Published in Cell reports (Cambridge) (22.06.2021)
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