Tg2576 mice have defective lipoprotein endocytosis
Riddell, D.R, Warwick, H.K, Cao, Z, Deng, K, Chin, J, Lou, Z, Saraf, K, Zhong, W, Von Schack, D, Wagner, E, Stewart, W, Aschmies, S, Monaghan, M, Pangalos, M.N, Reinhart, P.H
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
Astrocytes preferentially degrade apoE4: Impact on Aβ levels and neuronal plasticity in apoE targeted replacement mice
Riddell, David, Zhou, H, Atchison, K, Warwick, H, Atkinson, P, Stewart, W, Jefferson, J, Xu, L, Aschmies, S, Kirksey, Y, Hu, Y, Wagner, E, Parratt, A, Xu, J, Li, Z, Zaleska, M.M, Jacobsen, S.J, Pangalos, M, Reinhart, P
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
BACE1 is not the rate-limiting enzyme in Aβ production in the brains of APPswe transgenic mice: Pharmacological characterization of BACE1 using novel brain penetrant inhibitors
Riddell, D.R, Atchison, K, Yu, D, Turner, J, Wang, E, Gonzales, C, Warwick, H, Kim, J, Malamas, M, Wagner, E, Aschmies, S, Albinson, K, Erdel, J, Gunawan, I, Revilla-Sanchez, R, Takano, K, Warren, N, Fang, K, Bard, J, Hirst, W, Pangalos, M, Moss, S, Haydon, P.G, Robichaud, A, Reinhart, P
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
P1-055: Impaired induction of neuronal immediate-early gene expression correlates with contextual memory deficits in APP transgenic mice
Riddell, D.R, Warwick, H.K, Li, Z, Saraf, K, Zhong, W, von Schack, D, Comery, T.A, Aschmies, S, Monaghan, M, Braithwaite, S.P, Pangalos, M.N, Hirst, W.D, Reinhart, P.H
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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Journal Article
P2-306: Activation of both LXRα and LXRβ is required for TO901317-mediated lowering of Aβ42: implications for the development of Alzheimer's therapeutics
Riddell, D.R, Li, Z, Zhou, H, Aschmies, S, Kouranova, E, Ring, R, Warwick, H.W, Gustafsson, J.A, Steffensen, K.R, Pangalos, M.N, Jacobsen, S.J, Reinhart, P.H
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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Journal Article
P.3.d.019 Vabicaserin: effects of a novel 5-HT2C agonist on medial prefrontal cortex neurotransmission, cognition and sensorimotor gating
Rosenzweig-Lipson, S, Beyer, C.E, Hughes, Z, Lin, Q, Zhang, M.Y, Grauer, S, Aschmies, S, Comery, T, Stack, G, Marquis, K
Published in European neuropsychopharmacology (2007)
Published in European neuropsychopharmacology (2007)
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Journal Article
The LXR agonist TO901317 selectively lowers hippocampal A beta 42 and improves memory in the Tg2576 mouse model of Alzheimer's disease
Riddell, DR, Zhou, H, Comery, T A, Kouranova, E, Lo, C F, Warwick, H K, Ring, R H, Kirksey, Y, Aschmies, S, Xu, J, Kubek, K, Hirst, W D, Gonzales, C, Chen, Y, Murphy, E, Leonard, S, Vasylyev, D, Oganesian, A, Martone, R L, Pangalos, M N, Reinhart, PH, Jacobsen, J S
Published in Molecular and cellular neuroscience (01.04.2007)
Published in Molecular and cellular neuroscience (01.04.2007)
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Journal Article
Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease
Comery, Thomas A, Martone, Robert L, Aschmies, Suzan, Atchison, Kevin P, Diamantidis, George, Gong, Xiaohai, Zhou, Hua, Kreft, Anthony F, Pangalos, Menelas N, Sonnenberg-Reines, June, Jacobsen, J Steven, Marquis, Karen L
Published in The Journal of neuroscience (28.09.2005)
Published in The Journal of neuroscience (28.09.2005)
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Journal Article
In vitro pharmacological characterization and pro-cognitive effects of the selective alpha-7 nicotinic agonist WYE-103914
Dunlop, J., Comery, T.A., Lock, T., Kramer, A., Kowal, D., Yeola, S., Jow, F., Aschmies, S., Lin, Q., Beyer, C.E., Brennan, J., Kelley, C., Roncarati, R., Scali, C., Haydar, S., Ghiron, C., Marquis, K.L., Harrison, B., Robichaud, A., Terstappen, G.C.
Published in Biochemical pharmacology (01.10.2009)
Published in Biochemical pharmacology (01.10.2009)
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Journal Article
P1‐260: Tg2576 mice have defective lipoprotein endocytosis
Riddell, D.R., Warwick, H.K., Cao, Z., Deng, K., Chin, J., Lou, Z., Saraf, K., Zhong, W., Von Schack, D., Wagner, E., Stewart, W., Aschmies, S., Monaghan, M., Pangalos, M.N., Reinhart, P.H.
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
O2‐04‐02: Astrocytes preferentially degrade apoE4: Impact on Aβ levels and neuronal plasticity in apoE targeted replacement mice
Riddell, David, Zhou, H., Atchison, K., Warwick, H., Atkinson, P., Stewart, W., Jefferson, J., Xu, L., Aschmies, S., Kirksey, Y., Hu, Y., Wagner, E., Parratt, A., Xu, J., Li, Z., Zaleska, M.M., Jacobsen, S.J., Pangalos, M., Reinhart, P.
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
P3‐296: BACE1 is not the rate‐limiting enzyme in Aβ production in the brains of APPswe transgenic mice: Pharmacological characterization of BACE1 using novel brain penetrant inhibitors
Riddell, D.R., Atchison, K., Yu, D., Turner, J., Wang, E., Gonzales, C., Warwick, H., Kim, J., Malamas, M., Wagner, E., Aschmies, S., Albinson, K., Erdel, J., Gunawan, I., Revilla‐Sanchez, R., Takano, K., Warren, N., Fang, K., Bard, J., Hirst, W., Pangalos, M., Moss, S., Haydon, P.G., Robichaud, A., Reinhart, P.
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
Method for enhancing cognitive function
HIRST, WARREN D, ROSENZWEIG-LIPSON, SHARON JOY, SCHECHTER, LEE ERWIN, COMERY, THOMAS A, ASCHMIES, SUZAN
Year of Publication 01.04.2008
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Year of Publication 01.04.2008
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