Efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 4 infection: A pooled analysis
Asselah, Tarik, Reesink, Hendrik, Gerstoft, Jan, Ledinghen, Victor, Pockros, Paul J., Robertson, Michael, Hwang, Peggy, Asante‐Appiah, Ernest, Wahl, Janice, Nguyen, Bach‐Yen, Barr, Eliav, Talwani, Rohit, Serfaty, Lawrence
Published in Liver international (01.09.2018)
Published in Liver international (01.09.2018)
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Efficacy and safety of elbasvir/grazoprevir in participants with hepatitis C virus genotype 1, 4, or 6 infection from the Asia–Pacific region and Russia: Final results from the randomized C‐CORAL study
Wei, Lai, Jia, Ji Dong, Wang, Fu Sheng, Niu, Jun Qi, Zhao, Xu Min, Mu, Shengmei, Liang, Li Wen, Wang, Zaiqi, Hwang, Peggy, Robertson, Michael N, Ingravallo, Paul, Asante‐Appiah, Ernest, Wei, Bo, Evans, Barbara, Hanna, George J, Talwani, Rohit, Duan, Zhong Ping, Zhdanov, Konstantin, Cheng, Pin‐Nan, Tanwandee, Tawesak, Nguyen, Van Kinh, Heo, Jeong, Isakov, Vasily, George, Jacob
Published in Journal of gastroenterology and hepatology (01.01.2019)
Published in Journal of gastroenterology and hepatology (01.01.2019)
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Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers
Wang, I‐Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante‐Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi‐Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher
Published in Molecular systems biology (17.07.2012)
Published in Molecular systems biology (17.07.2012)
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Elbasvir/grazoprevir and sofosbuvir for hepatitis C virus genotype 3 infection with compensated cirrhosis: A randomized trial
Foster, Graham R., Agarwal, Kosh, Cramp, Matthew E., Moreea, Sulleman, Barclay, Stephen, Collier, Jane, Brown, Ashley S., Ryder, Stephen D., Ustianowski, Andrew, Forton, Daniel M., Fox, Ray, Gordon, Fiona, Rosenberg, William M., Mutimer, David J., Du, Jiejun, Gilbert, Christopher L., Asante‐Appiah, Ernest, Wahl, Janice, Robertson, Michael N., Barr, Eliav, Haber, Barbara
Published in Hepatology (Baltimore, Md.) (01.06.2018)
Published in Hepatology (Baltimore, Md.) (01.06.2018)
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Efficacy and safety of elbasvir/grazoprevir for 8 or 12 weeks for hepatitis C virus genotype 4 infection: A randomized study
Asselah, Tarik, Pol, Stanislas, Hezode, Christophe, Loustaud‐Ratti, Veronique, Leroy, Vincent, Ahmed, Si Nafa Si, Ozenne, Violaine, Bronowicki, Jean‐Pierre, Larrey, Dominique, Tran, Albert, Alric, Laurent, Nguyen‐Khac, Eric, Robertson, Michael N., Hanna, George J., Brown, Deborah, Asante‐Appiah, Ernest, Su, Feng‐Hsiu, Hwang, Peggy, Hall, Jessie Durrand, Guidoum, Amir, Hagen, Karin, Haber, Barbara A., Talwani, Rohit, Serfaty, Lawrence
Published in Liver international (01.05.2020)
Published in Liver international (01.05.2020)
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Efficacy and safety of ruzasvir 60 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4 or 6 infection
Lawitz, Eric, Poordad, Fred, Anderson, Leah J., Vesay, Michelle, Kelly, Michelle M., Liu, Hong, Gao, Wei, Fernsler, Doreen, Asante‐Appiah, Ernest, Robertson, Michael N., Hanna, George J., Barr, Eliav, Butterton, Joan, Kowdley, Kris V., Hassanein, Tarek, Sahota, Amandeep, Gordon, Stuart C., Yeh, Wendy W.
Published in Journal of viral hepatitis (01.06.2019)
Published in Journal of viral hepatitis (01.06.2019)
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Efficacy and safety of elbasvir/grazoprevir in treatment‐naive Chinese adults with hepatitis C virus infection: A randomized trial
Wei, Lai, Jia, Ji Dong, Duan, Zhong Ping, Wang, Fu Sheng, Niu, Jun Qi, Xie, Wen, Huang, Wen Xiang, Zhang, Ming Xiang, Huang, Yan, Wang, Mao Rong, Wu, Shan Ming, Zhao, Ying Ren, Jia, Zhan Sheng, Zhao, Xu Min, Mu, Sheng Mei, Liang, Li Wen, Wang, Zaiqi, Puenpatom, Amy, Hwang, Peggy, Robertson, Michael N., Ingravallo, Paul, Asante‐Appiah, Ernest, Wei, Bo, Evans, Barbara, Hanna, George J., Talwani, Rohit
Published in JGH open (01.12.2020)
Published in JGH open (01.12.2020)
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Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development
Martin, Elizabeth Anne, Lai, Ming-Tain, Ngo, Winnie, Feng, Meizhen, Graham, Donald, Hazuda, Daria J, Kumar, Sushma, Hwang, Carey, Sklar, Peter, Asante-Appiah, Ernest
Published in Journal of acquired immune deficiency syndromes (1999) (15.12.2020)
Published in Journal of acquired immune deficiency syndromes (1999) (15.12.2020)
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In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor
LAI, Ming-Tain, MEIZHEN FENG, CAUCHON, Elizabeth, CAMPEAU, Louis-Charles, GROBLER, Jay, YOUWEI YAN, DUCHARME, Yves, COTE, Bernard, ASANTE-APPIAH, Ernest, HAZUDA, Daria J, MILLER, Michael D, FALGUEYRET, Jean-Pierre, TAWA, Paul, WITMER, Marc, DISTEFANO, Daniel, YUAN LI, BURCH, Jason, SACHS, Nancy, MEIQING LU
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
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The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV Genotype 1a Replicons
Lahser, Frederick C, Bystol, Karin, Curry, Stephanie, McMonagle, Patricia, Xia, Ellen, Ingravallo, Paul, Chase, Robert, Liu, Rong, Black, Todd, Hazuda, Daria, Howe, Anita Y M, Asante-Appiah, Ernest
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
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Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons
Asante-Appiah, Ernest, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Nickle, David, Qiu, Ping, Howe, Anita, Lahser, Frederick C
Published in Antimicrobial agents and chemotherapy (01.07.2017)
Published in Antimicrobial agents and chemotherapy (01.07.2017)
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Safety and efficacy of elbasvir/grazoprevir in Asian participants with hepatitis C virus genotypes 1 and 4 infection
Wei, Lai, Kumada, Hiromitsu, Perumalswami, Ponni V, Tanwandee, Tawesak, Cheng, Wendy, Heo, Jeong, Cheng, Pin‐Nan, Hwang, Peggy, Mu, Sheng Mei, Zhao, Xu Min, Asante‐Appiah, Ernest, Caro, Luzelena, Hanna, George J, Robertson, Michael N, Haber, Barbara A, Talwani, Rohit
Published in Journal of gastroenterology and hepatology (01.09.2019)
Published in Journal of gastroenterology and hepatology (01.09.2019)
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Residues Distant from the Active Site Influence Protein-tyrosine Phosphatase 1B Inhibitor Binding
Montalibet, Jacqueline, Skorey, Kathryn, McKay, Dan, Scapin, Giovanna, Asante-Appiah, Ernest, Kennedy, Brian P.
Published in The Journal of biological chemistry (24.02.2006)
Published in The Journal of biological chemistry (24.02.2006)
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Protein Tyrosine Phosphatase-1B Dephosphorylation of the Insulin Receptor Occurs in a Perinuclear Endosome Compartment in Human Embryonic Kidney 293 Cells
Romsicki, Yolanda, Reece, Mark, Gauthier, Jacques-Yves, Asante-Appiah, Ernest, Kennedy, Brian P.
Published in The Journal of biological chemistry (26.03.2004)
Published in The Journal of biological chemistry (26.03.2004)
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Conformation-assisted Inhibition of Protein-tyrosine Phosphatase-1B Elicits Inhibitor Selectivity over T-cell Protein-tyrosine Phosphatase
Asante-Appiah, Ernest, Patel, Sangita, Desponts, Caroline, Taylor, Jillian M., Lau, Cheuk, Dufresne, Claude, Therien, Michel, Friesen, Rick, Becker, Joseph W., Leblanc, Yves, Kennedy, Brian P., Scapin, Giovanna
Published in The Journal of biological chemistry (24.03.2006)
Published in The Journal of biological chemistry (24.03.2006)
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The development of potent non-peptidic PTP-1B inhibitors
DUFRESNE, Claude, ROY, Patrick, WADDLETON, Deena, RAMACHANDRAN, Chidambaram, KENNEDY, Brian P, LIJING XU, GORDON, Robert, CHI CHUNG CHAN, LEBLANC, Yves, ZHAOYIN WANG, ASANTE-APPIAH, Ernest, CROMLISH, Wanda, BOIE, Yves, FORGHANI, Farnaz, DESMARAIS, Sylvie, QINGPING WANG, SKOREY, Kathryn
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
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The structure of apo protein‐tyrosine phosphatase 1B C215S mutant: More than just an S → O change
Scapin, Giovanna, Patel, Sangita, Patel, Vira, Kennedy, Brian, Asante‐Appiah, Ernest
Published in Protein science (01.08.2001)
Published in Protein science (01.08.2001)
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A Metal-induced Conformational Change and Activation of HIV-1 Integrase
Asante-Appiah, Ernest, Skalka, Anna Marie
Published in The Journal of biological chemistry (27.06.1997)
Published in The Journal of biological chemistry (27.06.1997)
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