Discovery of AS-0141, a Potent and Selective Inhibitor of CDC7 Kinase for the Treatment of Solid Cancers
Irie, Takayuki, Asami, Tokiko, Sawa, Ayako, Uno, Yuko, Taniyama, Chika, Funakoshi, Yoko, Masai, Hisao, Sawa, Masaaki
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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Journal Article
Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors
Irie, Takayuki, Asami, Tokiko, Sawa, Ayako, Uno, Yuko, Hanada, Mitsuharu, Taniyama, Chika, Funakoshi, Yoko, Masai, Hisao, Sawa, Masaaki
Published in European journal of medicinal chemistry (21.04.2017)
Published in European journal of medicinal chemistry (21.04.2017)
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Journal Article
Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton’s Tyrosine Kinase
Kawahata, Wataru, Asami, Tokiko, Kiyoi, Takao, Irie, Takayuki, Kashimoto, Shigeki, Furuichi, Hatsuo, Sawa, Masaaki
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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Journal Article
Design and Synthesis of Novel Amino-triazine Analogues as Selective Bruton’s Tyrosine Kinase Inhibitors for Treatment of Rheumatoid Arthritis
Kawahata, Wataru, Asami, Tokiko, Kiyoi, Takao, Irie, Takayuki, Taniguchi, Haruka, Asamitsu, Yuko, Inoue, Tomoko, Miyake, Takahiro, Sawa, Masaaki
Published in Journal of medicinal chemistry (11.10.2018)
Published in Journal of medicinal chemistry (11.10.2018)
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Journal Article
Characterization and Preclinical Evaluation of AS-1763, an Oral, Potent and Selective Noncovalent BTK Inhibitor, in Chronic Lymphocytic Leukemia
Tantawy, Shady I., Timofeeva, Natalia, Fujiwara, Hitomi, Hatakeyama, Mariko, Herrera, Breana, Loza, Lizbeth, Asami, Tokiko, Ohmoto, Hiroshi, Miyamoto, Kyoko, Nishioka, Yu, Arimura, Akinori, Sawa, Masaaki, Jain, Nitin, Gandhi, Varsha
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
TR-FRET binding assay targeting unactivated form of Bruton’s tyrosine kinase
Asami, Tokiko, Kawahata, Wataru, Sawa, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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Journal Article
‘Turn On/Off’ fluorescence probe for the screening of unactivated Bruton’s tyrosine kinase
Kawahata, Wataru, Asami, Tokiko, Fujii, Ikuo, Sawa, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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Journal Article
Abstract 1400: AS-1763: a highly potent, noncovalent and next generation BTK inhibitor for the treatment of patients with B-cell malignancies having C481S mutation in BTK
Kawahata, Wataru, Asami, Tokiko, Kiyoi, Takao, Irie, Takayuki, Kashimoto, Shigeki, Furuichi, Hatsuo, Sawa, Masaaki
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract A180: Discovery of furanone derivatives as novel Cdc7 inhibitors with anti-tumor activity
Irie, Takayuki, Asami, Tokiko, Sawa, Ayako, Taniyama, Chika, Funakoshi, Yoko, Uno, Yuko, Masai, Hisao, Sawa, Masaaki
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
신규 옥소이소퀴놀린 유도체
KAWAHATA WATARU, KIYOI TAKAO, ASAMI TOKIKO, IRIE TAKAYUKI, SAWA MASAAKI, KASHIMOTO SHIGEKI
Year of Publication 06.09.2019
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Year of Publication 06.09.2019
Patent
NOVEL OXOISOQUINOLINE DERIVATIVE
KASHIMOTO, Shigeki, ASAMI, Tokiko, KAWAHATA, Wataru, IRIE, Takayuki, KIYOI, Takao, SAWA, Masaaki
Year of Publication 31.05.2018
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Year of Publication 31.05.2018
Patent