Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy
Ravi, Rajani, Noonan, Kimberly A., Pham, Vui, Bedi, Rishi, Zhavoronkov, Alex, Ozerov, Ivan V., Makarev, Eugene, V. Artemov, Artem, Wysocki, Piotr T., Mehra, Ranee, Nimmagadda, Sridhar, Marchionni, Luigi, Sidransky, David, Borrello, Ivan M., Izumchenko, Evgeny, Bedi, Atul
Published in Nature communications (21.02.2018)
Published in Nature communications (21.02.2018)
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Journal Article
Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data
Aliper, Alexander, Plis, Sergey, Artemov, Artem, Ulloa, Alvaro, Mamoshina, Polina, Zhavoronkov, Alex
Published in Molecular pharmaceutics (05.07.2016)
Published in Molecular pharmaceutics (05.07.2016)
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Journal Article
Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response
Glaros, Vassilis, Rauschmeier, René, Artemov, Artem V., Reinhardt, Annika, Ols, Sebastian, Emmanouilidi, Aikaterini, Gustafsson, Charlotte, You, Yuanyuan, Mirabello, Claudio, Björklund, Åsa K., Perez, Laurent, King, Neil P., Månsson, Robert, Angeletti, Davide, Loré, Karin, Adameyko, Igor, Busslinger, Meinrad, Kreslavsky, Taras
Published in Immunity (Cambridge, Mass.) (14.09.2021)
Published in Immunity (Cambridge, Mass.) (14.09.2021)
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Journal Article
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate
Newton, Phillip T., Li, Lei, Zhou, Baoyi, Schweingruber, Christoph, Hovorakova, Maria, Xie, Meng, Sun, Xiaoyan, Sandhow, Lakshmi, Artemov, Artem V., Ivashkin, Evgeny, Suter, Simon, Dyachuk, Vyacheslav, El Shahawy, Maha, Gritli-Linde, Amel, Bouderlique, Thibault, Petersen, Julian, Mollbrink, Annelie, Lundeberg, Joakim, Enikolopov, Grigori, Qian, Hong, Fried, Kaj, Kasper, Maria, Hedlund, Eva, Adameyko, Igor, Sävendahl, Lars, Chagin, Andrei S.
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
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Journal Article
Design of efficient computational workflows for in silico drug repurposing
Vanhaelen, Quentin, Mamoshina, Polina, Aliper, Alexander M., Artemov, Artem, Lezhnina, Ksenia, Ozerov, Ivan, Labat, Ivan, Zhavoronkov, Alex
Published in Drug discovery today (01.02.2017)
Published in Drug discovery today (01.02.2017)
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Journal Article
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development
Ozerov, Ivan V., Lezhnina, Ksenia V., Izumchenko, Evgeny, Artemov, Artem V., Medintsev, Sergey, Vanhaelen, Quentin, Aliper, Alexander, Vijg, Jan, Osipov, Andreyan N., Labat, Ivan, West, Michael D., Buzdin, Anton, Cantor, Charles R., Nikolsky, Yuri, Borisov, Nikolay, Irincheeva, Irina, Khokhlovich, Edward, Sidransky, David, Camargo, Miguel Luiz, Zhavoronkov, Alex
Published in Nature communications (16.11.2016)
Published in Nature communications (16.11.2016)
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Journal Article
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Kameneva, Polina, Artemov, Artem V., Kastriti, Maria Eleni, Faure, Louis, Olsen, Thale K., Otte, Jörg, Erickson, Alek, Semsch, Bettina, Andersson, Emma R., Ratz, Michael, Frisén, Jonas, Tischler, Arthur S., de Krijger, Ronald R., Bouderlique, Thibault, Akkuratova, Natalia, Vorontsova, Maria, Gusev, Oleg, Fried, Kaj, Sundström, Erik, Mei, Shenglin, Kogner, Per, Baryawno, Ninib, Kharchenko, Peter V., Adameyko, Igor
Published in Nature genetics (01.05.2021)
Published in Nature genetics (01.05.2021)
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Journal Article
Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish
Kamenev, Dmitrii, Kaucka, Marketa, Kastriti, Maria Eleni, Zhou, Baoyi, Artemov, Artem V., Storer, Mekayla, Fried, Kaj, Adameyko, Igor, Dyachuk, Vyacheslav, Chagin, Andrei S.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2019)
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Journal Article
Genome-Wide DNA Methylation Profiling Reveals Epigenetic Adaptation of Stickleback to Marine and Freshwater Conditions
Artemov, Artem V, Mugue, Nikolai S, Rastorguev, Sergey M, Zhenilo, Svetlana, Mazur, Alexander M, Tsygankova, Svetlana V, Boulygina, Eugenia S, Kaplun, Daria, Nedoluzhko, Artem V, Medvedeva, Yulia A, Prokhortchouk, Egor B
Published in Molecular biology and evolution (01.09.2017)
Published in Molecular biology and evolution (01.09.2017)
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Journal Article
An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer
Artemov, Artem V., Zhenilo, Svetlana, Kaplun, Daria, Starshin, Alexey, Sokolov, Alexey, Mazur, Alexander M., Szpotan, Justyna, Gawronski, Maciej, Modrzejewska, Martyna, Gackowski, Daniel, Prokhortchouk, Egor B.
Published in Epigenetics (03.08.2022)
Published in Epigenetics (03.08.2022)
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Journal Article
Recurrent Translocations in Topoisomerase Inhibitor-Related Leukemia Are Determined by the Features of DNA Breaks Rather Than by the Proximity of the Translocating Genes
Lomov, Nikolai A., Viushkov, Vladimir S., Ulianov, Sergey V., Gavrilov, Alexey A., Alexeyevsky, Daniil A., Artemov, Artem V., Razin, Sergey V., Rubtsov, Mikhail A.
Published in International journal of molecular sciences (29.08.2022)
Published in International journal of molecular sciences (29.08.2022)
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Journal Article
CpG traffic lights are markers of regulatory regions in human genome
Lioznova, Anna V, Khamis, Abdullah M, Artemov, Artem V, Besedina, Elizaveta, Ramensky, Vasily, Bajic, Vladimir B, Kulakovskiy, Ivan V, Medvedeva, Yulia A
Published in BMC genomics (01.02.2019)
Published in BMC genomics (01.02.2019)
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Journal Article
Towards natural mimetics of metformin and rapamycin
Aliper, Alexander, Jellen, Leslie, Cortese, Franco, Artemov, Artem, Karpinsky-Semper, Darla, Moskalev, Alexey, Swick, Andrew G, Zhavoronkov, Alex
Published in Aging (Albany, NY.) (15.11.2017)
Published in Aging (Albany, NY.) (15.11.2017)
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Journal Article
Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis
Rauschmeier, René, Reinhardt, Annika, Gustafsson, Charlotte, Glaros, Vassilis, Artemov, Artem V, Dunst, Josefine, Taneja, Reshma, Adameyko, Igor, Månsson, Robert, Busslinger, Meinrad, Kreslavsky, Taras
Published in The Journal of experimental medicine (07.02.2022)
Published in The Journal of experimental medicine (07.02.2022)
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Journal Article
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
Laddach, Anna, Chng, Song Hui, Lasrado, Reena, Progatzky, Fränze, Shapiro, Michael, Erickson, Alek, Sampedro Castaneda, Marisol, Artemov, Artem V., Bon-Frauches, Ana Carina, Amaniti, Eleni-Maria, Kleinjung, Jens, Boeing, Stefan, Ultanir, Sila, Adameyko, Igor, Pachnis, Vassilis
Published in Nature communications (22.09.2023)
Published in Nature communications (22.09.2023)
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Journal Article
Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization
Cortese, Franco, Klokov, Dmitry, Osipov, Andreyan, Stefaniak, Jakub, Moskalev, Alexey, Schastnaya, Jane, Cantor, Charles, Aliper, Alexander, Mamoshina, Polina, Ushakov, Igor, Sapetsky, Alex, Vanhaelen, Quentin, Alchinova, Irina, Karganov, Mikhail, Kovalchuk, Olga, Wilkins, Ruth, Shtemberg, Andrey, Moreels, Marjan, Baatout, Sarah, Izumchenko, Evgeny, de Magalhães, João Pedro, Artemov, Artem V, Costes, Sylvain V, Beheshti, Afshin, Mao, Xiao Wen, Pecaut, Michael J, Kaminskiy, Dmitry, Ozerov, Ivan V, Scheibye-Knudsen, Morten, Zhavoronkov, Alex
Published in Oncotarget (06.03.2018)
Published in Oncotarget (06.03.2018)
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Journal Article
Serotonin limits generation of chromaffin cells during adrenal organ development
Kameneva, Polina, Melnikova, Victoria I., Kastriti, Maria Eleni, Kurtova, Anastasia, Kryukov, Emil, Murtazina, Aliia, Faure, Louis, Poverennaya, Irina, Artemov, Artem V., Kalinina, Tatiana S., Kudryashov, Nikita V., Bader, Michael, Skoda, Jan, Chlapek, Petr, Curylova, Lucie, Sourada, Lukas, Neradil, Jakub, Tesarova, Marketa, Pasqualetti, Massimo, Gaspar, Patricia, Yakushov, Vasily D., Sheftel, Boris I., Zikmund, Tomas, Kaiser, Jozef, Fried, Kaj, Alenina, Natalia, Voronezhskaya, Elena E., Adameyko, Igor
Published in Nature communications (25.05.2022)
Published in Nature communications (25.05.2022)
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Journal Article
Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla
Kameneva, Polina, V.Artemov, Artem, Kastriti, Maria Eleni, Sundström, Erik, Kharchenko, Peter V., Adameyko, Igor
Published in Cancer cell (10.05.2021)
Published in Cancer cell (10.05.2021)
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Journal Article
VHL inactivation without hypoxia is sufficient to achieve genome hypermethylation
Artemov, Artem V., Zhigalova, Nadezhda, Zhenilo, Svetlana, Mazur, Alexander M., Prokhortchouk, Egor B.
Published in Scientific reports (13.07.2018)
Published in Scientific reports (13.07.2018)
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Journal Article
Genomes of Strongylocentrotus franciscanus and Lytechinus variegatus: are there any genomic explanations for the two order of magnitude difference in the lifespan of sea urchins?
Sergiev, Petr V, Artemov, Artem A, Prokhortchouk, Egor B, Dontsova, Olga A, Berezkin, Grigory V
Published in Aging (Albany, NY.) (01.02.2016)
Published in Aging (Albany, NY.) (01.02.2016)
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Journal Article