Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models
Arntz, Onno J, Pieters, Bartijn C.H, Oliveira, Marina C, Broeren, Mathijs G.A, Bennink, Miranda B, Vries, Marieke, Lent, Peter L.E.M, Koenders, Marije I, den Berg, Wim B, der Kraan, Peter M, de Loo, Fons A.J
Published in Molecular nutrition & food research (01.09.2015)
Published in Molecular nutrition & food research (01.09.2015)
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Journal Article
Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β
Pieters, Bartijn C H, Arntz, Onno J, Bennink, Miranda B, Broeren, Mathijs G A, van Caam, Arjan P M, Koenders, Marije I, van Lent, Peter L E M, van den Berg, Wim B, de Vries, Marieke, van der Kraan, Peter M, van de Loo, Fons A J
Published in PloS one (30.03.2015)
Published in PloS one (30.03.2015)
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Journal Article
Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Cells
Mato-Basalo, Rocío, Morente-López, Miriam, Arntz, Onno J, van de Loo, Fons A J, Fafián-Labora, Juan, Arufe, María C
Published in International journal of molecular sciences (25.03.2021)
Published in International journal of molecular sciences (25.03.2021)
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Journal Article
Polyethylene glycol precipitation is an efficient method to obtain extracellular vesicle-depleted fetal bovine serum
Wang, Peng, Arntz, Onno J, Husch, Johanna F A, Kraan P M, Van der, Beucken, Jeroen J J P van den, van de Loo, Fons A J
Published in PloS one (05.12.2023)
Published in PloS one (05.12.2023)
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Journal Article
Flood Control: How Milk-Derived Extracellular Vesicles Can Help to Improve the Intestinal Barrier Function and Break the Gut-Joint Axis in Rheumatoid Arthritis
Aarts, Joyce, Boleij, Annemarie, Pieters, Bartijn C H, Feitsma, Anouk L, van Neerven, R J Joost, Ten Klooster, Jean Paul, M'Rabet, Laura, Arntz, Onno J, Koenders, Marije I, van de Loo, Fons A J
Published in Frontiers in immunology (28.07.2021)
Published in Frontiers in immunology (28.07.2021)
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Journal Article
An optimized method for plasma extracellular vesicles isolation to exclude the copresence of biological drugs and plasma proteins which impairs their biological characterization
Arntz, Onno J, Pieters, Bartijn C.H, van Lent, Peter L.E.M, Koenders, Marije I, van der Kraan, Peter M, van de Loo, Fons A.J
Published in PloS one (29.07.2020)
Published in PloS one (29.07.2020)
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Journal Article
Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing
Fafián-Labora, Juan, Morente-López, Miriam, Sánchez-Dopico, María José, Arntz, Onno J, van de Loo, Fons A J, De Toro, Javier, Arufe, María C
Published in Stem cell research & therapy (03.01.2020)
Published in Stem cell research & therapy (03.01.2020)
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Journal Article
Milk‐Derived Nanoparticle Fraction Promotes the Formation of Small Osteoclasts But Reduces Bone Resorption
Oliveira, Marina C., Di Ceglie, Irene, Arntz, Onno J., van den Berg, Wim B., van den Hoogen, Frank H.J., Ferreira, Adaliene V.M., van Lent, Peter L.E.M., van de Loo, Fons A.J.
Published in Journal of cellular physiology (01.01.2017)
Published in Journal of cellular physiology (01.01.2017)
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Journal Article
Rheumatoid Arthritis Patients With Circulating Extracellular Vesicles Positive for IgM Rheumatoid Factor Have Higher Disease Activity
Arntz, Onno J, Pieters, Bartijn C H, Thurlings, Rogier M, Wenink, Mark H, van Lent, Peter L E M, Koenders, Marije I, van den Hoogen, Frank H J, van der Kraan, Peter M, van de Loo, Fons A J
Published in Frontiers in immunology (29.10.2018)
Published in Frontiers in immunology (29.10.2018)
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Journal Article
Innate Immunity and Sex: Distinct Inflammatory Profiles Associated with Murine Pain in Acute Synovitis
Valdrighi, Natália, Blom, Arjen B, Vago, Juliana P, van Beuningen, Henk M, Vitters, Elly L, Helsen, Monique M, Walgreen, Birgitte, Arntz, Onno J, Koenders, Marije I, van der Kraan, Peter M, Blaney Davidson, Esmeralda N, van de Loo, Fons A J
Published in Cells (Basel, Switzerland) (01.07.2023)
Published in Cells (Basel, Switzerland) (01.07.2023)
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Journal Article
Profiling of plasma extracellular vesicles identifies proteins that strongly associate with patient's global assessment of disease activity in rheumatoid arthritis
Arntz, Onno J, Thurlings, Rogier M, Blaney Davidson, Esmeralda N, Jansen, Pascal W T C, Vermeulen, Michiel, Koenders, Marije I, van der Kraan, Peter M, van de Loo, Fons A J
Published in Frontiers in medicine (11.01.2024)
Published in Frontiers in medicine (11.01.2024)
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Journal Article
Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane
Broeren, Mathijs G A, de Vries, Marieke, Bennink, Miranda B, Arntz, Onno J, van Lent, Peter L E M, van der Kraan, Peter M, van den Berg, Wim B, van den Hoogen, Frank H J, Koenders, Marije I, van de Loo, Fons A J
Published in Arthritis research & therapy (12.08.2016)
Published in Arthritis research & therapy (12.08.2016)
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Journal Article
Intravenous delivery of HIV-based lentiviral vectors preferentially transduces F4/80+ and Ly-6C+ cells in spleen, important target cells in autoimmune arthritis
van den Brand, Ben T, Vermeij, Eline A, Waterborg, Claire E J, Arntz, Onno J, Kracht, Michael, Bennink, Miranda B, van den Berg, Wim B, van de Loo, Fons A J
Published in PloS one (04.02.2013)
Published in PloS one (04.02.2013)
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Journal Article
In Vivo Molecular Imaging of Cathepsin and Matrix Metalloproteinase Activity Discriminates between Arthritic and Osteoarthritic Processes in Mice
Vermeij, Eline A., Koenders, Marije I., Blom, Arjen B., Arntz, Onno J., Bennink, Miranda B., van den Berg, Wim B., van Lent, Peter L.E.M., van de Loo, Fons A.J.
Published in Molecular imaging (2014)
Published in Molecular imaging (2014)
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Journal Article
Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles
Blijdorp, Charles J, Tutakhel, Omar A Z, Hartjes, Thomas A, van den Bosch, Thierry P P, van Heugten, Martijn H, Rigalli, Juan Pablo, Willemsen, Rob, Musterd-Bhaggoe, Usha M, Barros, Eric R, Carles-Fontana, Roger, Carvajal, Cristian A, Arntz, Onno J, van de Loo, Fons A J, Jenster, Guido, Clahsen-van Groningen, Marian C, Cuevas, Cathy A, Severs, David, Fenton, Robert A, van Royen, Martin E, Hoenderop, Joost G J, Bindels, René J M, Hoorn, Ewout J
Published in Journal of the American Society of Nephrology (01.05.2021)
Published in Journal of the American Society of Nephrology (01.05.2021)
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Journal Article
Computational Design and Application of Endogenous Promoters for Transcriptionally Targeted Gene Therapy for Rheumatoid Arthritis
Geurts, Jeroen, Joosten, Leo AB, Takahashi, Nozomi, Arntz, Onno J, Glück, Anton, Bennink, Miranda B, van den Berg, Wim B, van de Loo, Fons AJ
Published in Molecular therapy (01.11.2009)
Published in Molecular therapy (01.11.2009)
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Journal Article
Deficiency of NADPH Oxidase Components p47phox and gp91phox Caused Granulomatous Synovitis and Increased Connective Tissue Destruction in Experimental Arthritis Models
van de Loo, Fons A.J., Bennink, Miranda B., Arntz, Onno J., Smeets, Ruben L., Lubberts, Erik, Joosten, Leo A.B., van Lent, Peter L.E.M., Coenen-de Roo, Christina J.J., Cuzzocrea, Salvatore, Segal, Brahm H., Holland, Steven M., van den Berg, Wim B.
Published in The American journal of pathology (01.10.2003)
Published in The American journal of pathology (01.10.2003)
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Journal Article
Bovine Milk‐Derived Extracellular Vesicles Inhibit Catabolic and Inflammatory Processes in Cartilage from Osteoarthritis Patients
Pieters, Bartijn C. H., Arntz, Onno J., Aarts, Joyce, Feitsma, Anouk L., Neerven, R. J. Joost, Kraan, Peter M., Oliveira, Marina C., Loo, Fons A. J.
Published in Molecular nutrition & food research (01.03.2022)
Published in Molecular nutrition & food research (01.03.2022)
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Journal Article
Protective Effect of Bovine Milk Extracellular Vesicles on Alveolar Bone Loss
Silva, Francine R. F., Heredia, Joyce E., Duffles, Letícia F., Arntz, Onno J., Teixeira, Mauro M., Ferreira, Adaliene V. M., Silva, Tarcilia A., van de Loo, Fons A. J., Macari, Soraia, Oliveira, Marina C.
Published in Molecular nutrition & food research (01.02.2024)
Published in Molecular nutrition & food research (01.02.2024)
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Journal Article
Extracellular vesicles regulate purinergic signaling and epithelial sodium channel expression in renal collecting duct cells
Barros Lamus, Eric R., Carotti, Valentina, Vries, Christine R. S., Witsel, Femke, Arntz, Onno J., Loo, Fons A. J., Carvajal, Cristian A., Bindels, René J. M., Hoenderop, Joost G. J., Rigalli, Juan P.
Published in The FASEB journal (01.05.2021)
Published in The FASEB journal (01.05.2021)
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Journal Article