Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
Armstrong, Lee A, Lange, Sven M, Dee Cesare, Virginia, Matthews, Stephen P, Nirujogi, Raja Sekhar, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G, Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh
Published in PloS one (16.07.2021)
Published in PloS one (16.07.2021)
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Journal Article
Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2
Abdul Rehman, Syed Arif, Armstrong, Lee A., Lange, Sven M., Kristariyanto, Yosua Adi, Gräwert, Tobias W., Knebel, Axel, Svergun, Dmitri I., Kulathu, Yogesh
Published in Molecular cell (21.10.2021)
Published in Molecular cell (21.10.2021)
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Journal Article
Structural basis for DNA 3'-end processing by human tyrosyl-DNA phosphodiesterase 1
Flett, Fiona J, Ruksenaite, Emilija, Armstrong, Lee A, Bharati, Shipra, Carloni, Roberta, Morris, Elizabeth R, Mackay, C Logan, Interthal, Heidrun, Richardson, Julia M
Published in Nature communications (02.01.2018)
Published in Nature communications (02.01.2018)
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Journal Article
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease
Lim, Chew Theng, Tan, Kang Wei, Wu, Mary, Ulferts, Rachel, Armstrong, Lee A, Ozono, Eiko, Drury, Lucy S, Milligan, Jennifer C, Zeisner, Theresa U, Zeng, Jingkun, Weissmann, Florian, Canal, Berta, Bineva-Todd, Ganka, Howell, Michael, O'Reilly, Nicola, Beale, Rupert, Kulathu, Yogesh, Labib, Karim, Diffley, John F X
Published in Biochemical journal (16.07.2021)
Published in Biochemical journal (16.07.2021)
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Journal Article
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains
Lange, Sven M., McFarland, Matthew R., Lamoliatte, Frederic, Carroll, Thomas, Krshnan, Logesvaran, Pérez-Ràfols, Anna, Kwasna, Dominika, Shen, Linnan, Wallace, Iona, Cole, Isobel, Armstrong, Lee A., Knebel, Axel, Johnson, Clare, De Cesare, Virginia, Kulathu, Yogesh
Published in Nature structural & molecular biology (08.07.2024)
Published in Nature structural & molecular biology (08.07.2024)
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Journal Article
Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
Armstrong, Lee A, Lange, Sven M, Cesare, Virginia De, Matthews, Stephen P, Nirujogi, Raja Sekhar, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G, Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh
Published in PloS one (16.04.2024)
Published in PloS one (16.04.2024)
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Journal Article
Comprehensive approach to study branched ubiquitin chains reveals roles for K48-K63 branches in VCP/p97-related processes
Lange, Sven M, Mcfarland, Matthew R, Lamoliatte, Frederic, Kwasna, Dominika, Linnan Shen, Wallace, Iona, Cole, Isobel, Armstrong, Lee A, Knebel, Axel, Johnson, Clare, De Cesare, Virginia, Kulathu, Yogesh
Published in bioRxiv (10.01.2023)
Published in bioRxiv (10.01.2023)
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Paper
Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies
Armstrong, Lee A, Lange, Sven M, De Cesare, Virginia, Matthews, Stephen P, Raja Sekar Nirujogi, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G, Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh
Published in bioRxiv (09.12.2020)
Published in bioRxiv (09.12.2020)
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