Increasing Melanoma Cell Death Using Inhibitors of Protein Disulfide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress
LOVAT, Penny E, CORAZZARI, Marco, ARMSTRONG, Jane L, MARTIN, Shaun, PAGLIARINI, Vittoria, HILL, David, BROWN, Anna M, PIACENTINI, Mauro, BIRCH-MACHIN, Mark A, REDFERN, Christopher P. F
Published in Cancer research (Chicago, Ill.) (01.07.2008)
Published in Cancer research (Chicago, Ill.) (01.07.2008)
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Journal Article
Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26): Synthesis and Biological Evaluation of Imidazole Methyl 3-(4-(aryl-2-ylamino)phenyl)propanoates
Gomaa, Mohamed S, Bridgens, Caroline E, Aboraia, Ahmed S, Veal, Gareth J, Redfern, Christopher P. F, Brancale, Andrea, Armstrong, Jane L, Simons, Claire
Published in Journal of medicinal chemistry (28.04.2011)
Published in Journal of medicinal chemistry (28.04.2011)
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Journal Article
Combining the Endoplasmic Reticulum Stress–Inducing Agents Bortezomib and Fenretinide as a Novel Therapeutic Strategy for Metastatic Melanoma
HILL, David S, MARTIN, Shaun, ARMSTRONG, Jane L, FLOCKHART, Ross, TONISON, Joge J, SIMPSON, Dominic G, BIRCH-MACHIN, Mark A, REDFERN, Christopher P. F, LOVAT, Penny E
Published in Clinical cancer research (15.02.2009)
Published in Clinical cancer research (15.02.2009)
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Journal Article
Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death
Armstrong, Jane L., Hill, David S., McKee, Christopher S., Hernandez-Tiedra, Sonia, Lorente, Mar, Lopez-Valero, Israel, Eleni Anagnostou, Maria, Babatunde, Fiyinfoluwa, Corazzari, Marco, Redfern, Christopher P.F., Velasco, Guillermo, Lovat, Penny E.
Published in Journal of investigative dermatology (01.06.2015)
Published in Journal of investigative dermatology (01.06.2015)
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Journal Article
Validation of epidermal AMBRA1 and loricrin (AMBLor) as a prognostic biomarker for nonulcerated American Joint Committee on Cancer stage I/II cutaneous melanoma
Ewen, Tom, Husain, Akhtar, Stefanos, Niki, Barrett, Paul, Jones, Claire, Ness, Tom, Long, Anna, Horswell, Stuart, Bosomworth, Helen, Lowenstein, Joe, Richardson, Grant, Swan, David, McConnell, Ashleigh, Rose, Aidan, Andrew, Tom, Reynolds, Nick, Malvehy, Josep, Carrera, Christina, Alos, Llucia, Mailer, Sonia, Helm, Thomas, Ding, Liang, Bogner, Paul, Podlipnik, Sebastian, Puig, Susana, McArthur, Grant A, Paragh, Gyorgy, Labus, Marie, Sloan, Philip, Armstrong, Jane L, Lovat, Penny E
Published in British journal of dermatology (1951) (15.03.2024)
Published in British journal of dermatology (1951) (15.03.2024)
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Journal Article
Oncogenic B-RAF Signaling in Melanoma Impairs the Therapeutic Advantage of Autophagy Inhibition
ARMSTRONG, Jane L, CORAZZARI, Marco, PIACENTINI, Mauro, LOVAT, Penny E, MARTIN, Shaun, PAGLIARINI, Vittoria, FALASCA, Laura, HILL, David S, ELLIS, Nicola, AL SABAH, Salim, REDFERN, Christopher P. F, FIMIA, Gian Maria
Published in Clinical cancer research (15.04.2011)
Published in Clinical cancer research (15.04.2011)
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Journal Article
Targeting X-Linked Inhibitor of Apoptosis Protein to Increase the Efficacy of Endoplasmic Reticulum Stress-Induced Apoptosis for Melanoma Therapy
Hiscutt, Emma L., Hill, David S., Martin, Shaun, Kerr, Ryan, Harbottle, Andrew, Birch-Machin, Mark, Redfern, Christopher P.F., Fulda, Simone, Armstrong, Jane L., Lovat, Penny E.
Published in Journal of investigative dermatology (01.09.2010)
Published in Journal of investigative dermatology (01.09.2010)
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Journal Article
Synthesis and Biological Evaluation of 3-(1H-Imidazol- and Triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl Derivatives as Small Molecule Inhibitors of Retinoic Acid 4-Hydroxylase (CYP26)
Gomaa, Mohamed S, Bridgens, Caroline E, Veal, Gareth J, Redfern, Christopher P. F, Brancale, Andrea, Armstrong, Jane L, Simons, Claire
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Journal Article
Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold
Gomaa, Mohamed S., Bridgens, Caroline E., Illingworth, Nicola A., Veal, Gareth J., Redfern, Christopher P.F., Brancale, Andrea, Armstrong, Jane L., Simons, Claire
Published in Bioorganic & medicinal chemistry (15.07.2012)
Published in Bioorganic & medicinal chemistry (15.07.2012)
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Journal Article
Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: Potent CYP26 inhibitors and enhancers of all- trans retinoic acid activity in neuroblastoma cells
Gomaa, Mohamed Sayed, Armstrong, Jane L., Bobillon, Beatrice, Veal, Gareth J., Brancale, Andrea, Redfern, Christopher P.F., Simons, Claire
Published in Bioorganic & medicinal chemistry (01.09.2008)
Published in Bioorganic & medicinal chemistry (01.09.2008)
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Journal Article
Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates
Gomaa, Mohamed S., Lim, Andrew S.T., Wilson Lau, S.C., Watts, Ann-Marie, Illingworth, Nicola A., Bridgens, Caroline E., Veal, Gareth J., Redfern, Christopher P.F., Brancale, Andrea, Armstrong, Jane L., Simons, Claire
Published in Bioorganic & medicinal chemistry (15.10.2012)
Published in Bioorganic & medicinal chemistry (15.10.2012)
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Journal Article
Role of Noxa in p53-independent fenretinide-induced apoptosis of neuroectodermal tumours
Armstrong, Jane L, Veal, Gareth J, Redfern, Christopher P F, Lovat, Penny E
Published in Apoptosis (London) (01.03.2007)
Published in Apoptosis (London) (01.03.2007)
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Journal Article
Regulation of Glycogen Synthesis by Amino Acids in Cultured Human Muscle Cells
Armstrong, Jane L., Bonavaud, Sylvie M., Toole, Barry J., Yeaman, Stephen J.
Published in The Journal of biological chemistry (12.01.2001)
Published in The Journal of biological chemistry (12.01.2001)
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Journal Article
The impact of retinoic acid treatment on the sensitivity of neuroblastoma cells to fenretinide
ARMSTRONG, Jane L, MARTIN, Shaun, ILLINGWORTH, Nicola A, JAMIESON, David, NEILSON, Abbie, LOVAT, Penny E, REDFERN, Chris P. F, VEAL, Gareth J
Published in Oncology reports (01.01.2012)
Published in Oncology reports (01.01.2012)
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