The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD
Markey, Kate A., Schluter, Jonas, Gomes, Antonio L.C., Littmann, Eric R., Pickard, Amanda J., Taylor, Bradford P., Giardina, Paul A., Weber, Daniela, Dai, Anqi, Docampo, Melissa D., Armijo, Gabriel K., Slingerland, Ann E., Slingerland, John B., Nichols, Katherine B., Brereton, Daniel G., Clurman, Annelie G., Ramos, Ruben J., Rao, Arka, Bush, Amy, Bohannon, Lauren, Covington, Megan, Lew, Meagan V., Rizzieri, David A., Chao, Nelson, Maloy, Molly, Cho, Christina, Politikos, Ioannis, Giralt, Sergio, Taur, Ying, Pamer, Eric G., Holler, Ernst, Perales, Miguel-Angel, Ponce, Doris M., Devlin, Sean M., Xavier, Joao, Sung, Anthony D., Peled, Jonathan U., Cross, Justin R., van den Brink, Marcel R.M.
Published in Blood (02.07.2020)
Published in Blood (02.07.2020)
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Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease
Burgos da Silva, Marina, Ponce, Doris M., Dai, Anqi, M. Devlin, Sean, Gomes, Antonio L. C., Moore, Gillian, Slingerland, John, Shouval, Roni, Armijo, Gabriel K., DeWolf, Susan, Fei, Teng, Clurman, Annelie, Fontana, Emily, Amoretti, Luigi A., Wright, Roberta J., Andrlova, Hana, Miltiadous, Oriana, Perales, Miguel-Angel, Taur, Ying, Peled, Jonathan U., van den Brink, Marcel R. M.
Published in Blood (01.12.2022)
Published in Blood (01.12.2022)
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Journal Article
Fecal microbiota diversity disruption and clinical outcomes after auto-HCT: a multicenter observational study
Khan, Niloufer, Lindner, Sarah, Gomes, Antonio L.C., Devlin, Sean M., Shah, Gunjan L., Sung, Anthony D., Sauter, Craig S., Landau, Heather J., Dahi, Parastoo B., Perales, Miguel-Angel, Chung, David J., Lesokhin, Alexander M., Dai, Anqi, Clurman, Annelie, Slingerland, John B., Slingerland, Ann E., Brereton, Daniel G., Giardina, Paul A., Maloy, Molly, Armijo, Gabriel K., Rondon-Clavo, Carlos, Fontana, Emily, Bohannon, Lauren, Ramalingam, Sendhilnathan, Bush, Amy T., Lew, Meagan V., Messina, Julia A., Littmann, Eric, Taur, Ying, Jenq, Robert R., Chao, Nelson J., Giralt, Sergio, Markey, Kate A., Pamer, Eric G., van den Brink, Marcel R.M., Peled, Jonathan U.
Published in Blood (18.03.2021)
Published in Blood (18.03.2021)
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Journal Article
Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease
Docampo, Melissa D., da Silva, Marina B., Lazrak, Amina, Nichols, Katherine B., Lieberman, Sophia R., Slingerland, Ann E., Armijo, Gabriel K., Shono, Yusuke, Nguyen, Chi, Monette, Sebastien, Dwomoh, Emmanuel, Lee, Nicole, Geary, Clair D., Perobelli, Suelen M., Smith, Melody, Markey, Kate A., Vardhana, Santosha A., Kousa, Anastasia I., Zamir, Eli, Greenfield, Itamar, Sun, Joseph C., Cross, Justin R., Peled, Jonathan U., Jenq, Robert R., Stein-Thoeringer, Christoph K., van den Brink, Marcel R.M.
Published in Blood (14.04.2022)
Published in Blood (14.04.2022)
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Journal Article
High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients
Nguyen, Chi L., Markey, Kate A., Miltiadous, Oriana, Dai, Anqi, Waters, Nicholas, Sadeghi, Keimya, Fei, Teng, Shouval, Roni, Taylor, Bradford P., Liao, Chen, Slingerland, John B., Slingerland, Ann E., Clurman, Annelie G., Maloy, Molly A., Bohannon, Lauren, Giardina, Paul A., Brereton, Daniel G., Armijo, Gabriel K., Fontana, Emily, Gradissimo, Ana, Gyurkocza, Boglarka, Sung, Anthony D., Chao, Nelson J., Devlin, Sean M., Taur, Ying, Giralt, Sergio A., Perales, Miguel-Angel, Xavier, Joao B., Pamer, Eric G., Peled, Jonathan U., Gomes, Antonio L.C., van den Brink, Marcel R.M.
Published in Cell (08.06.2023)
Published in Cell (08.06.2023)
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Journal Article
Early intestinal microbial features are associated with CD4 T-cell recovery after allogeneic hematopoietic transplant
Miltiadous, Oriana, Waters, Nicholas R., Andrlová, Hana, Dai, Anqi, Nguyen, Chi L., Burgos da Silva, Marina, Lindner, Sarah, Slingerland, John, Giardina, Paul, Clurman, Annelie, Armijo, Gabriel K., Gomes, Antonio L.C., Lakkaraja, Madhavi, Maslak, Peter, Scordo, Michael, Shouval, Roni, Staffas, Anna, O'Reilly, Richard, Taur, Ying, Prockop, Susan, Boelens, Jaap Jan, Giralt, Sergio, Perales, Miguel-Angel, Devlin, Sean M., Peled, Jonathan U., Markey, Kate A., van den Brink, Marcel R.M.
Published in Blood (05.05.2022)
Published in Blood (05.05.2022)
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Journal Article
MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT
Andrlová, Hana, Miltiadous, Oriana, Kousa, Anastasia I, Dai, Anqi, DeWolf, Susan, Violante, Sara, Park, Hee-Yon, Janaki-Raman, Sudha, Gardner, Rui, El Daker, Sary, Slingerland, John, Giardina, Paul, Clurman, Annelie, Gomes, Antonio L C, Nguyen, Chi, da Silva, Marina Burgos, Armijo, Gabriel K, Lee, Nicole, Zappasodi, Roberta, Chaligne, Ronan, Masilionis, Ignas, Fontana, Emily, Ponce, Doris, Cho, Christina, Bush, Amy, Hill, Lauren, Chao, Nelson, Sung, Anthony D, Giralt, Sergio, Vidal, Esther H, Hosszu, Kinga K, Devlin, Sean M, Peled, Jonathan U, Cross, Justin R, Perales, Miguel-Angel, Godfrey, Dale I, van den Brink, Marcel R M, Markey, Kate A
Published in Science translational medicine (25.05.2022)
Published in Science translational medicine (25.05.2022)
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Journal Article
Profiling the Fungal Microbiome after Fecal Microbiota Transplantation for Graft-versus-Host Disease: Insights from a Phase 1 Interventional Study
van Lier, Yannouck F., Rolling, Thierry, Armijo, Gabriel K., Zhai, Bing, Haverkate, Nienke J.E., Meijer, Ellen, Nur, Erfan, Blom, Bianca, Peled, Jonathan U., van den Brink, Marcel R.M., Hohl, Tobias M., Hazenberg, Mette D., Markey, Kate A.
Published in Transplantation and cellular therapy (01.01.2023)
Published in Transplantation and cellular therapy (01.01.2023)
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Journal Article
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease
Lindner, Sarah, Miltiadous, Oriana, Ramos, Ruben J. F., Paredes, Jenny, Kousa, Anastasia I., Dai, Anqi, Fei, Teng, Lauder, Emma, Frame, John, Waters, Nicholas R., Sadeghi, Keimya, Armijo, Gabriel K., Ghale, Romina, Victor, Kristen, Gipson, Brianna, Monette, Sebastien, Russo, Marco Vincenzo, Nguyen, Chi L., Slingerland, John, Taur, Ying, Markey, Kate A., Andrlova, Hana, Giralt, Sergio, Perales, Miguel-Angel, Reddy, Pavan, Peled, Jonathan U., Smith, Melody, Cross, Justin R., Burgos da Silva, Marina, Campbell, Clarissa, van den Brink, Marcel R. M.
Published in Nature microbiology (01.03.2024)
Published in Nature microbiology (01.03.2024)
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Journal Article
Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation
Peled, Jonathan U, Gomes, Antonio L.C, Devlin, Sean M, Littmann, Eric R, Taur, Ying, Sung, Anthony D, Weber, Daniela, Hashimoto, Daigo, Slingerland, Ann E, Slingerland, John B, Maloy, Molly, Clurman, Annelie G, Stein-Thoeringer, Christoph K, Markey, Kate A, Docampo, Melissa D, Burgos da Silva, Marina, Khan, Niloufer, Gessner, André, Messina, Julia A, Romero, Kristi, Lew, Meagan V, Bush, Amy, Bohannon, Lauren, Brereton, Daniel G, Fontana, Emily, Amoretti, Luigi A, Wright, Roberta J, Armijo, Gabriel K, Shono, Yusuke, Sanchez-Escamilla, Míriam, Castillo Flores, Nerea, Alarcon Tomas, Ana, Lin, Richard J, Yáñez San Segundo, Lucrecia, Shah, Gunjan L, Cho, Christina, Scordo, Michael, Politikos, Ioannis, Hayasaka, Kasumi, Hasegawa, Yuta, Gyurkocza, Boglarka, Ponce, Doris M, Barker, Juliet N, Perales, Miguel-Angel, Giralt, Sergio A, Jenq, Robert R, Teshima, Takanori, Chao, Nelson J, Holler, Ernst, Xavier, Joao B, Pamer, Eric G, van den Brink, Marcel R.M
Published in The New England journal of medicine (27.02.2020)
Published in The New England journal of medicine (27.02.2020)
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Journal Article
Highly Selective Irreversible ITK Inhibitor Cpi-818 Reduces Acute Graft-Versus Host Disease
Lindner, Sarah, Lee, Nicole, Armijo, Gabriel K, Burgos da Silva, Marina D, Herrera, Pamela S, Nguyen, Chi L, Dwomoh, Emmanuel A, Ghale, Romina, Smith, Melody, Perales, Miguel-Angel, Markey, Kate A, Buggy, Joseph J, Janc, James W, van den Brink, Marcel
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Microbial Bile Acid Metabolism Shapes Effector T Cell Responses during Inflammation in Mouse and Human
Lindner, Sarah, Miltiadous, Oriana, Ramos, Ruben J, Dai, Anqi, Kousa, Anastasia, Armijo, Gabriel K, Ghale, Romina, Nguyen, Chi L, Paredes Sanchez, Jenny, Fei, Teng, Frame V, John W, Monette, Sebastien, Fontana, Emily, Slingerland, John, Taur, Ying, Burgos da Silva, Marina D, Markey, Kate A, Peled, Jonathan U, Smith, Melody, Giralt, Sergio A, Perales, Miguel-Angel, Cross, Justin R, Campbell, Clarissa, van den Brink, Marcel R M
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
MAIT and Vδ2 Unconventional T Cells Predict Favorable Outcome after Allogeneic HCT and Are Supported By a Diverse Intestinal Microbiome
Andrlova, Hana, Miltiadous, Oriana, Dai, Anqi, Gardner, Rui, El Daker, Sary, Slingerland, John B, Giardina, Paul A, Clurman, Annelie, Gomes, Antonio L.C., Nguyen, Chi L., Burgos da Silva, Marina D, DeWolf, Susan, Armijo, Gabriel K, Lee, Nicole, Zappasodi, Roberta, Fontana, Emily, Ponce, Doris M, Cho, Christina, Giralt, Sergio A, Devlin, Sean M, Peled, Jonathan U, Cross, Justin, Perales, Miguel-Angel, Godfrey, Dale I, van den Brink, Marcel, Markey, Kate A
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
The Intestinal Microbiota Correlates with Response and Toxicity after CAR T Cell Therapy in Patients with B-Cell Malignancies
Smith, Melody, Dai, Anqi, Ghilardi, Guido, Amelsberg, Kimberly, Devlin, Sean M, Pajarillo, Raymone, Slingerland, John B, Beghi, Silvia, Herrera, Pamela S, Giardina, Paul A, Clurman, Annelie, Dwomoh, Emmanuel A, Armijo, Gabriel K, Gomes, Antonio L.C., Littmann, Eric R, Schluter, Jonas, Fontana, Emily, Taur, Ying, Park, Jae H, Palomba, Maria Lia, Halton, Elizabeth, Ruiz, Josel D, Jain, Tania, Pennisi, Martina, Afuye, Aishat Olaide, Perales, Miguel-Angel, Freyer, Craig W., Garfall, Alfred L, Gier, Shannon H, Nasta, Sunita, Landsburg, Daniel J, Gerson, James N, Svoboda, Jakub, Cross, Justin, Chong, Elise A, Giralt, Sergio A, Gill, Saar, Rivière, Isabelle, Porter, David L, Schuster, Stephen J, Sadelain, Michel, Frey, Noelle V, Brentjens, Renier J, June, Carl H, Pamer, Eric G, Peled, Jonathan U, Ruella, Marco, van den Brink, Marcel, Facciabene, Andrea
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Profiling the fungal microbiome after FMT for graft-versus-host disease: insights from a phase 1 interventional study
van Lier, Yannouck F., Rolling, Thierry, Armijo, Gabriel K., Zhai, Bing, Haverkate, Nienke J.E., Meijer, Ellen, Nur, Erfan, Blom, Bianca, Peled, Jonathan U., van den Brink, Marcel R.M., Hohl, Tobias M., Hazenberg, Mette D., Markey, Kate A.
Published in Transplantation and cellular therapy (21.10.2022)
Published in Transplantation and cellular therapy (21.10.2022)
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Journal Article
322 - Microbial Bile Acid Metabolism Shapes Effector T Cell Responses during Graft-Versus-Host Disease in Mouse and Human
Lindner, Sarah, Miltiadous, Oriana, Ramos, Ruben, Dai, Anqi, Kousa, Anastasia, Sanchez, Jenny Paredes, Fei, Teng, Frame, John, Nguyen, Chi L., Armijo, Gabriel K, Ghale, Romina, Monette, Sebastien, Slingerland, John, Andrlova, Hana, da Silva, Marina Burgos, Taur, Ying, Markey, Kate Ann, Peled, Jonathan U., Smith, Melody, Giralt, Sergio A, Perales, Miguel-Angel, Cross, Justin R., Campbell, Clarissa, van den Brink, Marcel R.M.
Published in Transplantation and cellular therapy (01.02.2023)
Published in Transplantation and cellular therapy (01.02.2023)
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Journal Article
Microbial Bile Acid Metabolism Shapes Effector T Cell Responses during Graft-Versus-Host Disease in Mouse and Human
Lindner, Sarah, Miltiadous, Oriana, Ramos, Ruben, Dai, Anqi, Kousa, Anastasia, Sanchez, Jenny Paredes, Fei, Teng, Frame, John, Nguyen, Chi L., Armijo, Gabriel K, Ghale, Romina, Monette, Sebastien, Slingerland, John, Andrlova, Hana, da Silva, Marina Burgos, Taur, Ying, Markey, Kate Ann, Peled, Jonathan U., Smith, Melody, Giralt, Sergio A, Perales, Miguel-Angel, Cross, Justin R., Campbell, Clarissa, van den Brink, Marcel R.M.
Published in Transplantation and cellular therapy (01.02.2023)
Published in Transplantation and cellular therapy (01.02.2023)
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Journal Article
Intestinal Microbiota Composition and Diversity Are Associated with CD4 T Cell Reconstitution after Allogeneic Hematopoietic Cell Transplantation
Miltiadous, Oriana, Andrlova, Hana, Dai, Anqi, Nguyen, Chi, da Silva, Marina Burgos, Gomes, Antonio, Lindner, Sarah, Slingerland, John, Giardina, Paul, Clurman, Annelie, Armijo, Gabriel K, Lakkaraja, Madhavi, Scordo, Michael, O’Reilly, Richard J., Prockop, Susan E., Boelens, Jaap Jan, Giralt, Sergio A, Perales, Miguel, Devlin, Sean M., van den Brink, Marcel R.M., Peled, Jonathan U., Markey, Kate Ann
Published in Transplantation and cellular therapy (01.03.2021)
Published in Transplantation and cellular therapy (01.03.2021)
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