The timeline of epigenetic drug discovery: from reality to dreams
Ganesan, A, Arimondo, Paola B, Rots, Marianne G, Jeronimo, Carmen, Berdasco, María
Published in Clinical epigenetics (02.12.2019)
Published in Clinical epigenetics (02.12.2019)
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Journal Article
triple helix: 50 years later, the outcome
Duca, Maria, Vekhoff, Pierre, Oussedik, Kahina, Halby, Ludovic, Arimondo, Paola B
Published in Nucleic acids research (01.09.2008)
Published in Nucleic acids research (01.09.2008)
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Journal Article
DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge
Castillo-Aguilera, Omar, Depreux, Patrick, Halby, Ludovic, Arimondo, Paola B, Goossens, Laurence
Published in Biomolecules (Basel, Switzerland) (05.01.2017)
Published in Biomolecules (Basel, Switzerland) (05.01.2017)
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Journal Article
The DNMT3A R882H mutant displays altered flanking sequence preferences
Emperle, Max, Rajavelu, Arumugam, Kunert, Stefan, Arimondo, Paola B, Reinhardt, Richard, Jurkowska, Renata Z, Jeltsch, Albert
Published in Nucleic acids research (06.04.2018)
Published in Nucleic acids research (06.04.2018)
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Journal Article
A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation
Yakhou, Lounis, Azogui, Anaelle, Gupta, Nikhil, Richard Albert, Julien, Miura, Fumihito, Ferry, Laure, Yamaguchi, Kosuke, Battault, Sarah, Therizols, Pierre, Bonhomme, Frédéric, Bethuel, Elouan, Sarkar, Arpita, Greenberg, Maxim V C, Arimondo, Paola B, Cristofari, Gael, Kirsh, Olivier, Ito, Takashi, Defossez, Pierre-Antoine
Published in Nucleic acids research (27.10.2023)
Published in Nucleic acids research (27.10.2023)
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Journal Article
Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells
Valente, Sergio, Liu, Yiwei, Schnekenburger, Michael, Zwergel, Clemens, Cosconati, Sandro, Gros, Christina, Tardugno, Maria, Labella, Donatella, Florean, Cristina, Minden, Steven, Hashimoto, Hideharu, Chang, Yanqi, Zhang, Xing, Kirsch, Gilbert, Novellino, Ettore, Arimondo, Paola B, Miele, Evelina, Ferretti, Elisabetta, Gulino, Alberto, Diederich, Marc, Cheng, Xiaodong, Mai, Antonello
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Journal Article
Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation
Hammam, Elie, Sinha, Ameya, Baumgarten, Sebastian, Nardella, Flore, Liang, Jiaqi, Miled, Samia, Bonhomme, Frédéric, Erdmann, Diane, Arcangioli, Benoit, Arimondo, Paola B, Dedon, Peter, Preiser, Peter, Scherf, Artur
Published in mBio (21.12.2021)
Published in mBio (21.12.2021)
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Journal Article
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine
Champion, Christine, Guianvarc'h, Dominique, Sénamaud-Beaufort, Catherine, Jurkowska, Renata Z, Jeltsch, Albert, Ponger, Loïc, Arimondo, Paola B, Guieysse-Peugeot, Anne-Laure
Published in PloS one (24.08.2010)
Published in PloS one (24.08.2010)
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Journal Article
Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells
Yamaguchi, Kosuke, Chen, Xiaoying, Rodgers, Brianna, Miura, Fumihito, Bashtrykov, Pavel, Bonhomme, Frédéric, Salinas-Luypaert, Catalina, Haxholli, Deis, Gutekunst, Nicole, Aygenli, Bihter Özdemir, Ferry, Laure, Kirsh, Olivier, Laisné, Marthe, Scelfo, Andrea, Ugur, Enes, Arimondo, Paola B., Leonhardt, Heinrich, Kanemaki, Masato T., Bartke, Till, Fachinetti, Daniele, Jeltsch, Albert, Ito, Takashi, Defossez, Pierre-Antoine
Published in Nature communications (05.04.2024)
Published in Nature communications (05.04.2024)
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Journal Article
Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein
Bon, Corentin, Si, Yang, Pernak, Melanie, Barbachowska, Magdalena, Levi-Acobas, Eva, Cadet Daniel, Veronique, Jallet, Corinne, Ruzic, Dusan, Djokovic, Nemanja, Djikić, Teodora, Nikolic, Katarina, Halby, Ludovic, Arimondo, Paola B
Published in Molecules (Basel, Switzerland) (31.08.2021)
Published in Molecules (Basel, Switzerland) (31.08.2021)
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Journal Article
Direct Synthesis of Allyl Amines with 2‐Nitrosulfonamide Derivatives via the Tsuji‐Trost Reaction
Bon, Corentin, Arimondo, Paola B., Halby, Ludovic
Published in ChemistryOpen (Weinheim) (01.12.2021)
Published in ChemistryOpen (Weinheim) (01.12.2021)
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Journal Article
Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies
Gros, Christina, Chauvigné, Laura, Poulet, Anaïs, Menon, Yoann, Ausseil, Frédéric, Dufau, Isabelle, Arimondo, Paola B
Published in Nucleic acids research (01.10.2013)
Published in Nucleic acids research (01.10.2013)
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Journal Article
Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines
Marques-Magalhães, Ângela, Graça, Inês, Miranda-Gonçalves, Vera, Henrique, Rui, Lopez, Marie, Arimondo, Paola B., Jerónimo, Carmen
Published in Biomedicine & pharmacotherapy (01.09.2021)
Published in Biomedicine & pharmacotherapy (01.09.2021)
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Journal Article
Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites
Reyser, Thibaud, Paloque, Lucie, Nguyen, Michel, Augereau, Jean-Michel, Fuchter, Matthew John, Lopez, Marie, Arimondo, Paola B., Hassell-Hart, Storm, Spencer, John, Di Stefano, Luisa, Benoit-Vical, Françoise
Published in Pharmaceutics (01.10.2023)
Published in Pharmaceutics (01.10.2023)
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Journal Article
The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor
Luviano, Nelia, Lopez, Marie, Gawehns, Fleur, Chaparro, Cristian, Arimondo, Paola B, Ivanovic, Slavica, David, Patrice, Verhoeven, Koen, Cosseau, Céline, Grunau, Christoph
Published in Epigenetics & chromatin (26.10.2021)
Published in Epigenetics & chromatin (26.10.2021)
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Journal Article
Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest
Lobo, João, Cardoso, Ana Rita, Miranda-Gonçalves, Vera, Looijenga, Leendert H J, Lopez, Marie, Arimondo, Paola B, Henrique, Rui, Jerónimo, Carmen
Published in Pharmaceutics (07.01.2021)
Published in Pharmaceutics (07.01.2021)
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Journal Article
DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies
Pechalrieu, Dany, Etievant, Chantal, Arimondo, Paola B.
Published in Biochemical pharmacology (01.04.2017)
Published in Biochemical pharmacology (01.04.2017)
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Journal Article
DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness
Carrier, Arnaud, Desjobert, Cécile, Ponger, Loic, Lamant, Laurence, Bustos, Matias, Torres-Ferreira, Jorge, Henrique, Rui, Jeronimo, Carmen, Lanfrancone, Luisa, Delmas, Audrey, Favre, Gilles, Daunay, Antoine, Busato, Florence, Hoon, Dave S B, Tost, Jorg, Etievant, Chantal, Riond, Joëlle, Arimondo, Paola B
Published in eLife (20.09.2022)
Published in eLife (20.09.2022)
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Journal Article
Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity
Rotili, Dante, Tarantino, Domenico, Marrocco, Biagina, Gros, Christina, Masson, Véronique, Poughon, Valérie, Ausseil, Fréderic, Chang, Yanqi, Labella, Donatella, Cosconati, Sandro, Di Maro, Salvatore, Novellino, Ettore, Schnekenburger, Michael, Grandjenette, Cindy, Bouvy, Celine, Diederich, Marc, Cheng, Xiaodong, Arimondo, Paola B, Mai, Antonello
Published in PloS one (08.05.2014)
Published in PloS one (08.05.2014)
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